Lifeboat Foundation

The short-term effectiveness of a two-dose regimen of the BioNTech/Pfizer mRNA BNT162b2 severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) vaccine was widely demonstrated. However, long term effectiveness is still unknown. Leveraging the centralized computerized database of Maccabi Healthcare Services (MHS), we assessed the correlation between time-from-vaccine and incidence of breakthrough infection between June 1 and July 27, the date of analysis. After controlling for potential confounders as age and comorbidities, we found a significant 1.51 fold (95% CI, 1.38−1.66) increased risk for infection for early vaccinees compared to those vaccinated later that was similar across all ages groups. The increased risk reached 2.26-fold (95% CI, 1.80−3.01) when comparing those who were vaccinated in January to those vaccinated in April. This preliminary finding of vaccine waning as a factor of time from vaccince should prompt further investigations into long-term protection against different strains.

The duration of effectiveness of SARS-CoV-2 vaccination is not yet known. Here, the authors present preliminary evidence of BNT162b2 vaccine waning across all age groups above 16, with a higher incidence of infection in people who received their second dose early in 2021 compared to later in the year.

What’s New: Today, Intel celebrates the 50th anniversary of the Intel® 4,004, the world’s first commercially available microprocessor. With its launch in November 1971, the 4,004 paved the path for modern microprocessor computing – the “brains” that make possible nearly every modern technology, from the cloud to the edge. Microprocessors enable the convergence of the technology superpowers – ubiquitous computing, pervasive connectivity, cloud-to-edge infrastructure and artificial intelligence – and create a pace of innovation that is moving faster today than ever.

“This year marks the 50th anniversary of the 4,004 chip. Think of how much we’ve accomplished in the past half-century. This is a sacred moment for technology. This is what made computing really take off!” –Pat Gelsinger, Intel CEO

Why It’s Important: The 4,004 is the pioneer microprocessor, and its success proved that it was possible to build complex integrated circuits and fit them on a chip the size of a fingernail. Its invention also established a new random logic design methodology, one that subsequent generations of microprocessors would be built upon, before evolving to create the chips found in today’s modern devices.

“If you want to measure something with very high precision, you almost always use an optical interferometer, because light makes for a very precise ruler,” says Jaime Cardenas, assistant professor of optics at the University of Rochester.

Now, the Cardenas Lab has created a way to make these optical workhorses even more useful and sensitive. Meiting Song, a Ph.D. student, has for the first time packaged an experimental way of amplifying interferometric signals—without a corresponding increase in extraneous, unwanted input, or “noise”—on a 1 mm by 1 mm integrated photonic chip. The breakthrough, described in Nature Communications, is based on a theory of weak value amplification with waveguides that was developed by Andrew Jordan, a professor of physics at Rochester, and students in his lab.

It reduces the operational carbon footprint while making inspections more efficient and cost-effective.

In the race toward practical fusion energy, tokamaks (donut-shaped plasma devices) are the leading concept—they have achieved better confinement and higher plasma temperatures than any other configuration. Two major magnetic fields are used to contain the plasma: a toroidal field (along the axes of the donut) produced by external coils and the field from a ring current flowing in the plasma itself. The performance of a tokamak, however, comes with an Achilles heel—the possibility of disruptions, a sudden termination of the plasma driven by instabilities in the plasma current. Since the plasma current provides the equilibrium and confinement for the tokamak, the challenge of taming disruptions must be addressed and solved.

As the magnitudes of the plasma current and plasma energy increase, disruptions can cause more damage. As such, they are a particularly important concern for the newest and most powerful machines, such as the SPARC tokamak. SPARC is a compact, high-magnetic–field tokamak under design and in the early stages of construction by a joint team from the Massachusetts Institute of Technology and Commonwealth Fusion Systems. The SPARC plasma is predicted to produce more than 10 times the power than is required to maintain its 250 million F temperatures. All tokamaks of this performance class must develop strategies to protect the machine against disruptions.

A solution, however, may be in hand. Prompted by a theoretical idea from Prof. Allen Boozer of Columbia University, the SPARC design includes an innovative new coil structure which promises fully passive protection from the threat of runaway electrons.

A long-term fallout of the Covid crisis has been the rise of the contactless enterprise, in which customers, and likely employees, interact with systems to get what they need or request. This means a pronounced role for artificial intelligence and machine learning, or conversational AI, which add the intelligence needed to deliver superior customer or employee experience.

Deloitte analysts recently analyzed patents in the area of conversational AI to assess the direction of the technology and the market — and the technology has been fast developing. “Rapid adoption of conversational AI will likely be underpinned by innovations in the various steps of chatbot development that have the potential to hasten the creation and training of chatbots and enable them to efficiently handle complex requests — with a personal touch,” the analyst team, led by Deloitte’s Sherry Comes, observes.

Conversational AI is a ground-breaking application for AI, agrees Chris Hausler, director of data science for Zendesk. “Organizations saw a massive 81% increase in customer interactions with automated bots last year, and no doubt these will continue to be key to delivering great experiences.”

Inventors from more than 40 countries are in Qatar for the week-long Challenge and Innovation Forum on technology.
Super computers, cloud technology and robots are among the innovations on display.
Al Jazeera’s Victoria Gatenby reports from Doha.

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Putin stressed that the work on a unified system of reference data for shaping the program was already underway at the Ministry.

“The key task here is to ensure the weapon systems and equipment that will be manufactured and supplied to the armed forces under this program should reliably protect Russia from potential threats,” he concluded.

Germany’s COVID infections are now higher than ever. And the numbers keep growing.

That’s despite a relatively high vaccination rate. Almost 70 percent of Germans are fully vaccinated against the virus.

Continue reading “COVID-19 infections are rising dramatically in Germany | COVID-19 Special” »