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Summary: A newly developed artificial intelligence model can detect Parkinson’s disease by reading a person’s breathing patterns. The algorithm can also discern the severity of Parkinson’s disease and track progression over time.

Source: MIT

Parkinson’s disease is notoriously difficult to diagnose as it relies primarily on the appearance of motor symptoms such as tremors, stiffness, and slowness, but these symptoms often appear several years after the disease onset.

A new study in Science overthrew the whole gamebook. Led by Dr. David Baker at the University of Washington, a team tapped into an AI’s “imagination” to dream up a myriad of functional sites from scratch. It’s a machine mind’s “creativity” at its best—a deep learning algorithm that predicts the general area of a protein’s functional site, but then further sculpts the structure.

As a reality check, the team used the new software to generate drugs that battle cancer and design vaccines against common, if sometimes deadly, viruses. In one case, the digital mind came up with a solution that, when tested in isolated cells, was a perfect match for an existing antibody against a common virus. In other words, the algorithm “imagined” a hotspot from a viral protein, making it vulnerable as a target to design new treatments.

The algorithm is deep learning’s first foray into building proteins around their functions, opening a door to treatments that were previously unimaginable. But the software isn’t limited to natural protein hotspots. “The proteins we find in nature are amazing molecules, but designed proteins can do so much more,” said Baker in a press release. The algorithm is “doing things that none of us thought it would be capable of.”

As the size of modern technology shrinks down to the nanoscale, weird quantum effects—such as quantum tunneling, superposition, and entanglement—become prominent. This opens the door to a new era of quantum technologies, where quantum effects can be exploited. Many everyday technologies make use of feedback control routinely; an important example is the pacemaker, which must monitor the user’s heartbeat and apply electrical signals to control it, only when needed. But physicists do not yet have an equivalent understanding of feedback control at the quantum level. Now, physicists have developed a “master equation” that will help engineers understand feedback at the quantum scale. Their results are published in the journal Physical Review Letters.

“It is vital to investigate how feedback control can be used in quantum technologies in order to develop efficient and fast methods for controlling quantum systems, so that they can be steered in real time and with high precision,” says co-author Björn Annby-Andersson, a quantum physicist at Lund University, in Sweden.

An example of a crucial feedback-control process in quantum computing is quantum error correction. A quantum computer encodes information on physical qubits, which could be photons of light, or atoms, for instance. But the quantum properties of the qubits are fragile, so it is likely that the encoded information will be lost if the qubits are disturbed by vibrations or fluctuating electromagnetic fields. That means that physicists need to be able to detect and correct such errors, for instance by using feedback control. This error correction can be implemented by measuring the state of the qubits and, if a deviation from what is expected is detected, applying feedback to correct it.

Circa 2019 face_with_colon_three Biological singularity here we come :3.

Scientific Reports volume 9, Article number: 12,181 (2019) Cite this article.

Given the potential scope and capabilities of quantum technology, it is absolutely crucial not to repeat the mistakes made with AI—where regulatory failure has given the world algorithmic bias that hypercharges human prejudices, social media that favors conspiracy theories, and attacks on the institutions of democracy fueled by AI-generated fake news and social media posts. The dangers lie in the machine’s ability to make decisions autonomously, with flaws in the computer code resulting in unanticipated, often detrimental, outcomes. In 2021, the quantum community issued a call for action to urgently address these concerns. In addition, critical public and private intellectual property on quantum-enabling technologies must be protected from theft and abuse by the United States’ adversaries.

https://urldefense.com/v3/__https:/www.youtube.com/watch?v=5…MexaVnE%24

There are national defense issues involved as well. In security technology circles, the holy grail is what’s called a cryptanalytically relevant quantum computer —a system capable of breaking much of the public-key cryptography that digital systems around the world use, which would enable blockchain cracking, for example. That’s a very dangerous capability to have in the hands of an adversarial regime.

Continue reading “Quantum computing is an even bigger threat than artificial intelligence” »

We need the computers and sensors to better our lives, to allow everyone access to the wisdom of the ages. We can’t collect all the data ourselves and try to make sense of it without machines because our brains aren’t up to the task. Imagine if every little decision everyone has made over the past thousand years along with its outcome had been recorded on index cards and stored in a gargantuan facility somewhere. Remember that giant warehouse at the end of the first Indiana Jones movie where they ended up storing the Ark of the Covenant? That’s where index cards AA through AC are housed. Imagine five thousand more of those to store all that data. What could we do with it? Nothing useful.

Computers can do only one thing: manipulate ones and zeros in memory. But they can do that at breathtaking speeds with perfect accuracy. Our challenge is getting all that data into the digital mirror, to copy our analog lives in their digital brains. Cheap sensors and computers will do this for us, with prices that fall every year and capabilities that increase.

Coupling massive processing power with sensors will create a species-level brain and memory. Instead of being billions of separate people with siloed knowledge, we will become billions of people who share a single vast intellect. Comparisons to The Matrix are easy to make but are not really apropos. We aren’t talking about a world without human agency but with enhanced agency, information-based agency. Making decisions informed by data is immeasurably better. Even if someone ignores the suggestion of the digital mirror, they are richer for knowing it. Imagine having an AI that could not only tell you what you should do but would allow you to insert your own values into the decision process. In fact, the system would learn your values from your actions, and the suggestions it gives you would be different from those it would give everyone else, as they should be. If knowledge is power, such a system is by definition the ultimate in empowerment. Every person on the planet could effectively be smarter and wiser than anyone who has ever lived.

Scientists in the Netherlands combined a functional MRI scanner with a powerful AI algorithm to reconstruct visual stimuli.

An algorithm developed by researchers from Helmholtz Munich, the Technical University of Munich (TUM) and its University Hospital rechts der Isar, the University Hospital Bonn (UKB) and the University of Bonn is able to learn independently across different medical institutions. The key feature is that it is self-learning, meaning it does not require extensive, time-consuming findings or markings by radiologists in the MRI images.

This federated algorithm was trained on more than 1,500 MRI scans of healthy study participants from four institutions while maintaining data privacy. The algorithm then was used to analyze more than 500 patient MRI scans to detect diseases such as multiple sclerosis, vascular disease, and various forms of brain tumors that the algorithm had never seen before. This opens up new possibilities for developing efficient AI-based federated algorithms that learn autonomously while protecting privacy. The study has now been published in the journal Nature Machine Intelligence.

Health care is currently being revolutionized by artificial intelligence. With precise AI solutions, doctors can be supported in diagnosis. However, such algorithms require a considerable amount of data and the associated radiological specialist findings for training. The creation of such a large, central database, however, places special demands on data protection. Additionally, the creation of the findings and annotations, for example the marking of tumors in an MRI image, is very time-consuming.

Why we should be performing interstellar archaeology and how Avi Loeb and his team at the Galileo Project plan to recover an interstellar object at the bottom of the ocean.

“Any chemically-propelled spacecraft sent by past civilizations into interstellar space, like the five we had sent so far (Voyager 1 & 2, Pioneer 10 & 11, and New Horizons), remained gravitationally bound to the Milky Way long after these civilizations died. Their characteristic speed of tens of kilometers per second is an order of magnitude smaller than the escape speed out of the Milky Way. These rockets would populate the Milky Way disk and move around at similar speeds to the stars in it.

Continue reading “Why a Group of Scientists Plan to Search for Alien Technology with Avi Loeb” »