Lifeboat Foundation

Exposure to environmental pollutants can cause alterations in brain development that affect sexual development and fertility for several generations, according to findings to be presented in Lyon, at the European Society of Endocrinology annual meeting, ECE 2019. The offspring of pregnant rats exposed to a mixture of common endocrine-disrupting chemicals (EDCs), at doses equivalent to those commonly experienced by people, showed impairments in sexual development and maternal behaviour that were passed on through several generations. These findings suggest that current levels of endocrine-disrupting chemicals in our environment may already be causing long-lasting harm and that people and agencies should take measures to minimise exposure.

Endocrine-disrupting chemicals can interfere with the normal function of our hormones and have previously been associated with infertility and altered sexual development in animals and people. We are exposed to hundreds of these pollutants in our daily lives, as they are used in the manufacture of plastics, pesticides and medicines. However, the extent of damage being done to our health and the consequences to future generations remains unclear. Rodent studies have suggested that exposure to EDCs can affect brain development through several generations but the generational effects on sexual development and reproduction have not previously been investigated.

In this study, David Lopez Rodriguez a graduate student in Anne-Simone Parent’s lab at the University of Liege in Belgium monitored the sexual development of three generations of rats, whose parent generation only were exposed to a mixture of common EDCs during pregnancy and lactation. The female rats born in the first and second generation showed impairments in their care for their own pups. However, the female rats in the second and third generation exhibited a delayed onset of puberty and altered reproductive cycle and ovarian follicle development, indicating that their fertility was affected, even though they were never themselves exposed to the EDCs. These changes were associated with altered gene expression in their brains that are known to affect how reproductive hormones are regulated.

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Nearly a year in space changed Scott Kelly’s genes, brain function and more, NASA’s Twin Study shows.

Deadly Germs, Lost Cures

In its decision to approve two drugs for orange and grapefruit trees, the E.P.A. largely ignored objections from the C.D.C. and the F.D.A., which fear that expanding their use in cash crops could fuel antibiotic resistance in humans.

An orange picker collecting oranges on a grove in Zolfo Springs, Fla. Credit Credit.

Continue reading “Citrus Farmers Facing Deadly Bacteria Turn to Antibiotics, Alarming Health Officials” »

A groundbreaking project to tackle one of the world’s most pressing and complex health challenges—antimicrobial resistance (AMR)—has secured a $1 million boost. UTS will lead a consortium of 26 researchers from 14 organisations in the development of an AMR ‘knowledge engine’ capable of predicting outbreaks and informing interventions, supported by a grant from the Medical Research Future Fund.

“AMR is not a simple problem confined to health and hospital settings,” explains project Chief Investigator, UTS Professor of Infectious Disease Steven Djordjevic. “Our pets and livestock rely on many of these same medicines, so they find their way into the food chain and into the environment through animal faeces.”

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As the number of electronics devices increases around the world, finding effective methods of recycling electronic waste (e-waste) is a growing concern. About 50 million tons of e-waste is generated each year and only 20% of that is recycled. Most of the remaining 80% ends up in a landfill where it can become an environmental problem. Currently, e-waste recycling involves mechanical crushers and chemical baths, which are expensive, and manual labor, which can cause significant health and environmental problems when not performed properly. Thus, researchers from Kumamoto University, Japan have been using pulsed power (pulsed electric discharges) to develop a cleaner and more efficient recycling method.

Pulsed power has been shown to be successful in processing various waste materials, from concrete to waste water. To test its ability to be used in e-waste recycling, researchers examined its effectiveness in separating components found in one of the most prolific types of e-waste, CD ROMs. In previous work, they showed that complete separation of metal from plastic occurred using 30 pulses at about 35 J/pulse (At the current price of electricity in Tokyo, this amount of energy costs about 0.4 Yen for recycling 100 CD ROMs). To examine the mechanism of material separation using this method, researchers performed further analyses by observing the plasma discharge with a high-speed camera, by taking schlieren visualizations to assess the shock wave, and using shadowgraph images to measure fragment motion.

Images at the early stage of electrical discharge showed two distinct light emissions: blue-white and orange. These indicated excitation of aluminum and upper protective plastic materials respectively. After the plasma dissipated, fragments of metal and plastic could be seen flying away from the CD ROM sample.

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A sensational new study conducted at the University of Copenhagen disproves traditional knowledge of stem cell development. The study reveals that the destiny of intestinal cells is not predetermined, but instead determined by the cells’ surroundings. The new knowledge may make it easier to manipulate stem cells for stem cell therapy. The results have been published in Nature.

All cells in the foetal gut have the potential to develop into stem cells, a new study conducted at the Faculty of Health and Medical Sciences at the University of Copenhagen concludes. The researchers behind the study have discovered that the development of immature intestinal cells—contrary to previous assumptions—is not predetermined, but affected by the cells’ immediate surroundings in the intestines. This discovery may ease the path to effective stem cell therapy, says Associate Professor Kim Jensen from the Biotech Research & Innovation Centre (BRIC) and the Novo Nordisk Foundation Center for Stem Cell Biology (DanStem).

“We used to believe that a cell’s potential for becoming a stem cell was predetermined, but our new results show that all immature cells have the same probability for becoming stem cells in the fully developed organ. In principle, it is simply a matter of being in the right place at the right time. Here signals from the cells’ surroundings determine their fate. If we are able to identify the signals that are necessary for the immature cell to develop into a stem cell, it will be easier for us to manipulate cells in the wanted direction.”

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New York City is set to get a new radiation-treatment center, nearly a decade in the making, that uses proton beams to treat cancerous tumors.

Called the New York Proton Center, it is a for-profit partnership of Memorial Sloan Kettering Cancer Center, Montefiore Health System and Mount Sinai Health System, managed by the ProHEALTH company. Financing for the center was provided in part by the hospitals.

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Air pollution is responsible for millions of deaths every year, worldwide. According to a State of Global Air report, air pollution is the fifth greatest global mortality risk.

“Air pollution is the fifth highest cause of death among all health risks, ranking just below smoking; each year, more people die from air pollution related disease than from road traffic injuries or malaria.”

No wonder, then, that when Google.org issued an open call to organizations around the world to submit ideas for how they could use AI for societal challenges, Google chose one of the 20 winning organizations as one that was out to address pollution.

Continue reading “Eyes in the sky project will show power plant pollution marks” »