Lifeboat Foundation

Bacteria found in the human gut could save countless lives by transforming type A or type B blood into type O.

At a meeting of the American Chemical Society today, Steve Withers of the University of British Colombia presented new research suggesting enzymes found in gut bacteria could effectively strip antigens from the two most common blood types. If successful, the discovery would essentially make most types of blood accessible to those who need it, regardless of their blood type.

If you’ve read some of my latest articles, you might remember that I’ve been spending some time in my hometown. My quasi-holiday is not over yet, but my stay in my hometown pretty much is; I’m leaving in a few hours.

During my stay, I’ve told my girlfriend many times that wandering around my hometown feels like having someone else’s memories implanted in my head. I’ve never considered myself too attached to the place where I grew up, but after years of absence, I’ve become even less so. It’s like the place doesn’t have an effect on me anymore; it can’t really influence me. I know my way around it and I remember where landmarks and things are, but there’s little emotional connection left. It’s almost like being a tourist. Even my own room, which used to be pretty much my realm up until I was 18, now feels just like any regular room—in no small part because it has changed quite a bit since then. Given a few more years, I might lose all feelings for the place.

This shouldn’t be a surprise. Your feelings for places and people change and sometimes fade away altogether, over the years. This happens within currently normal lifetimes; what is going to happen if and when our lives last for centuries?

Healthy diet linked to healthy aging and longer telomeres, a new study on 5000 healthy adults. Relationship significant in women. … All four diets emphasize eating plenty of fruits, vegetables, whole grains and plant-based protein and limiting consumption of sugar, sodium and red and processed meat. Overall, the findings suggest that following these guidelines is associated with longer telomere length and reduces the risk of major chronic disease…”

Eating a diet that is rich in fruits, vegetables and whole grains and low in added sugar, sodium and processed meats could help promote healthy cellular aging in women, according to a new study published in the American Journal of Epidemiology.

“The key takeaway is that following a healthy diet can help us maintain healthy cells and avoid certain chronic diseases,” said lead author Cindy Leung, assistant professor of nutritional sciences at the University of Michigan School of Public Health. “Emphasis should be placed on improving the overall quality of your diet rather than emphasizing individual foods or nutrients.”

Continue reading “Healthy diet linked to healthy cellular aging in women” »

A new study showed physical activity might lower cardiovascular disease risk by improving blood vessel function.

Adults in their early 60s, who spend less time sitting and more time engaged in light to vigorous physical activity, benefit with healthier levels of heart and vessel disease markers, according to new research in Journal of the American Heart Association, the Open Access Journal of the American Heart Association/American Stroke Association.

The results from increased physical activity were found to be particularly good among women.

Continue reading “Older adults who get physical can lower their heart disease risk” »

A new family of enzymes found in the human gut has been used to quickly turn type A blood into type O — which can be used for transfusions in anyone.

Click on photo to start video.

Today we will be taking a look at a new paper that shows inhibiting TGFβ can boost liver regeneration.

If you like watching these streams and/or would like to participate in future streams, please consider supporting us by becoming a Lifespan Hero: https://www.lifespan.io/hero

Continue reading “Journal Club August 2018 — TGFβ inhibition restores liver regeneration” »

It’s an unfortunate fact of life that as we get older, our cells gradually lose the ability to heal themselves. Thankfully, at least one aspect of that might be treatable in the near future, if new work from Georgia Tech pans out. Researchers have developed a hydrogel that holds muscle stem cells, and by injecting this near the site of a muscle injury they can get to work repairing it. The team says the technique could be effective at treating injuries in the elderly and people with muscular dystrophy.

The Arctic permafrost really should stay frozen. In many places it’s been frozen for tens of thousands of years, locking away greenhouse gasses and ancient diseases.

Unfortunately, our planet’s changing climate is denting permafrosts around the world. And now NASA-funded research has confirmed that the expected gradual thawing of the Arctic permafrost is being dramatically sped up by a natural phenomenon known as thermokarst lakes.

Continue reading “Strange Lakes Are Speeding Up Arctic Permafrost Melt, And That’s Really Bad News” »

Today, we would like to share with you the talk given by Kelsey Moody, CEO of Biotech Company Ichor, at the recent Ending Age-Related Diseases: Investment Prospects & Advances in Research conference in New York City. In this talk, Kelsey discusses Ichor’s protein engineering platform, how Ichor has used it, and Ichor’s plans for using it to discover new classes of drugs for age-related diseases.

Kelsey is a process-oriented biotechnology executive who has specialized in the study of aging and aging mechanisms for over a decade. Since 2013, he has successfully built Ichor Therapeutics from a living room start-up into a premier, vertically integrated contract research organization that focuses on preclinical research services for aging pathways. Proceeds from this work are used to self-fund R&D initiatives that constitute Ichor’s portfolio companies in enzyme therapy (Lysoclear, Inc.), small molecule drug discovery (Antoxerene, Inc.), and protein engineering (RecombiPure, Inc.) Kelsey has received graduate-level training in medicine, business, and laboratory research.