Lifeboat Foundation

For years immunotherapy has held huge promise. Finally, it seems to be coming to fruition with hopes for a cancer vaccine in the near future…

A disease-carrying, newly invasive tick to the United States, the Asian longhorned tick, is poised to spread across much of North America, suggests a new study published Thursday in the Journal of Medical Entomology. According to the study, the tick might be able to live anywhere from Southeastern Canada to most of the eastern half of the U.S. and even parts of the West Coast.

The Asian longhorned tick, or Haemaphysalis longicornis, made an unwelcome splash last year, when researchers and health officials discovered it on a pet sheep in New Jersey. Any hopes that the discovery was an isolated incident faded away this year, with sightings of the tick popping up again in New Jersey and eight other states this past spring and summer (Arkansas, Connecticut, Maryland, New York, North Carolina, Pennsylvania, Virginia, and West Virginia). Since 2017, the tick has been found on pets, farm animals, and at least two people in the U.S., and it’s possible that it might have made its way here at least as early as 2010.

For decades after the discovery of DNA, researchers mostly thought of genetics in terms of genes, the pieces or sequences of DNA that encode instructions for building proteins in cells. Then scientists discovered that genes make up just 2 percent of our DNA and that most genetic complexity stems from the vast non-gene code, which influences when genes are turned on or off. Further, half of that non-gene code was found to come from insertions of viral DNA. Consequently, say the authors, genetic variation, and the potential for disease-causing mistakes, occurs in transposons as well as in genes.

New laboratory techniques can identify which of our genes are influenced by DNA snippets that are left behind in our genetic code by viruses, a new study finds.

In November, Dr. Aubrey de Grey, a graduate of the University of Cambridge, was in Spain to attend the Longevity World Forum in the city of Valencia, and he gave a press conference organized by his friend, MIT engineer José Luis Cordeiro.

Dr. Aubrey de Grey is the scientific director (CSO) and founder of the SENS Research Foundation. In Madrid and Valencia, Dr. de Grey reaffirmed for Tendencias21 one of his most striking statements of 2018: “In the future, there will be many different medicines to reverse aging. In five years, we will have many of them working in early clinical trials.”

The Longevity World Forum is a congress on longevity and genomics in Europe. It is heir to the first congress in Spain, the International Longevity and Cryopreservation Summit, which was held at the CSIC headquarters in Madrid in May 2017, and Dr. de Grey also participated in that event. In Valencia, his presentation was recieved with interest, and Dr. de Grey explained to this select audience that aging will be treated as a medical problem in the near future. Rather than treating its symptoms using the infectious disease model, the root causes of aging will themselves be treated.

Cancer research is an area of medical science that, rightfully, gets considerable attention. There are nearly 14.5 million Americans with a history of cancer and with more than 13 million estimated new cancer cases each year. It’s no wonder even artificial intelligence (AI) has gotten into the field. Researchers from the University of Michigan are not getting left behind, with a groundbreaking method that has the potential to eliminate tumors.

This new technology uses nano-sized discs, about 10 nm to be exact, to teach the body to kill cancer cells. “We are basically educating the immune system with these nanodiscs so that immune cells can attack cancer cells in a personalized manner,” said James Moon from the University of Michigan.

Each of these ‘nanodiscs’ is full of neoantigens (tumor-specific mutations) that teach the immune system’s T-cells to recognize each neoantigen and kill them. These work hand-in-hand with immune checkpoint inhibitors that boost the responses of T-cells — forming an anti-cancer system in the body that wipes out tumors and potentially keeps them from reemerging.

Continue reading “Researchers Develop Nanodiscs That Can Wipe Out Tumors” »

Most people don’t see and experience the most exciting astronomical events not because they don’t care, but because they don’t make a plan. So here’s some advance warning. 2019 will start with a rare ‘Super Blood Wolf Moon’ eclipse, but it’s only the first of many incredible stargazing events in 2019. From eclipses and comets to supermoons and a Transit of Mercury, here’s exactly when, where and why to look up at the night sky during 2019.

1 – Super Blood Wolf Moon Eclipse

When: Sunday/Monday, January 20/21, 2019

Researchers at the University of Texas at Arlington have recently explored the use of machine learning for emotion recognition based solely on paralinguistic information. Paralinguistics are aspects of spoken communication that do not involve words, such as pitch, volume, intonation, etc.

Recent advances in machine learning have led to the development of tools that can recognize emotional states by analyzing images, voice recordings, electroencephalograms or electrocardiograms. These tools could have several interesting applications, for instance, enabling more efficient human-computer interactions in which a computer recognizes and responds to a human user’s emotions.

“In general, one may argue that speech carries two distinct types of information: explicit or linguistic information, which concerns articulated patterns by the speaker; and implicit or paralinguistic information, which concerns the variation in pronunciation of the linguistic patterns,” the researchers wrote in their paper, published in the Advances in Experimental Medicine and Biology book series. “Using either or both types of information, one may attempt to classify an audio segment that consists of speech, based on the emotion(s) it carries. However, emotion recognition from speech appears to be a significantly difficult task even for a human, no matter if he/she is an expert in this field (e.g. a psychologist).”

Continue reading “Emotion recognition based on paralinguistic information” »

It’s officially deadlier than heroin in the United States.

How would you like to take one injection that has multiple genes that improve cellular repair and regeneration, keeping your cells younger and healthier longer? Today, BioViva and Rutgers University are embarking on an ambitious research project to do just that; we are tackling humanities greatest foe — suffering and death due to aging.

Read the press release here:

https://www.eurekalert.org/pub_releases/2018-12/bui-rua121018.php