Lifeboat Foundation

There is a challenge related to prostate cancer from cancer cells that form resistance to treatments as the disease progresses. For medical science, these resistance mechanisms are not yet fully understood.

A new study by the University of Eastern Finland has filled some of this knowledge gap. The scientists found that inflammation-promoting immune cells, M1 macrophages, can transform cancer cells into stem-like cells and thus immune to treatment.

The study examined the impact of factors promoting inflammation in a tumour microenvironment on the progression of prostate cancer. Researchers focused particularly on the role of M1 and M2 macrophages in the tumour microenvironment. Macrophages are immune cells whose large number in the tumour area is often a sign of poor prognosis in relation to prostate cancer. These white blood cells stimulate the action of other immune system cells.

A collection of perforated pebbles from an archaeological site in Israel may be spindle whorls, representing a key milestone in the development of rotational tools including wheels, according to a study published November 13, 2024 in the open-access journal PLOS ONE by Talia Yashuv and Leore Grosman from the Hebrew University of Jerusalem, Israel.

Non-invasive BCIs let you harness tech benefits and enhance cognition without implanting a brain chip.

The problem with conventional non-invasive BCIs is that they are not as accurate as invasive BCIs. They collect data using external sensors that are not in direct contact with brain tissues, and any disturbance in a user’s surroundings could affect their function.

Continue reading “AI-powered non-invasive BCIs to help you control objects by thought” »

Supported, in part, by NASA and administrated by Resources for the Future, Kevin Boyle and colleagues from Moravian University, Penn State, and the University of Rhode Island have assessed the feasibility of implementing a smartphone app designed to convey cholera risk forecasts to households to mitigate the threat of cholera in Bangladesh. This forms part of early warning measures.

The research is titled “Early warning systems, mobile technology, and cholera aversion: Evidence from rural Bangladesh,” and it appears in the Journal of Environmental Economics and Management.

For the research, the team developed CholeraMap, an Android-based smartphone application that conveys cholera risk forecasts to households. The app enables users to access risk predictions – from low to medium to high – for both their community and individual home locations.

In the quest to uncover the fundamental particles and forces of nature, one of the critical challenges facing high-energy experiments at the Large Hadron Collider (LHC) is ensuring the quality of the vast amounts of data collected. To do this, data quality monitoring systems are in place for the various subdetectors of an experiment and they play an important role in checking the accuracy of the data.

Summary: A recent study offers new insights into how brain regions coordinate during rest, using resting-state fMRI (rsfMRI) and neural recordings in mice. By comparing blood flow patterns with direct neural activity, researchers found that some brain activity remains “invisible” in traditional rsfMRI scans. This hidden activity suggests that current brain imaging techniques may miss key elements of neural behavior.

The findings, potentially applicable to human studies, may refine our understanding of brain networks. Further research could improve the accuracy of interpreting brain activity.

This study explores how muscle contractions, such as those that occur during exercise, influence motor neurons—the cells responsible for controlling muscle movement.

There’s no doubt that exercise does a body good. Regular activity not only strengthens muscles but can bolster our bones, blood vessels, and immune system.

Now, MIT engineers have found that exercise can also have benefits at the level of individual neurons. They observed that when muscles contract during exercise, they release a soup of biochemical signals called myokines.

Continue reading “When muscles work out, they help neurons grow: Biochemical and physical effects of exercise could help heal nerves” »

An international team led by the University of Geneva (UNIGE) has identified three ultra-massive galaxies—nearly as massive as the Milky Way—already in place within the first billion years after the Big Bang.