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Rip Kepler 🕊


CAPE CANAVERAL, Fla. (AP) — NASA’s elite planet-hunting spacecraft has been declared dead, just a few months shy of its 10th anniversary.

Officials announced the Kepler Space Telescope’s demise Tuesday.

Already well past its expected lifetime, the 9 1/2-year-old Kepler had been running low on fuel for months. Its ability to point at distant stars and identify possible alien worlds worsened dramatically at the beginning of October, but flight controllers still managed to retrieve its latest observations. The telescope has now gone silent, its fuel tank empty.

The October Journal Club will be focusing on a new study in worms where a combination of compounds acted in synergy to almost double lifespan.


SUMMARY There is growing interest in pharmacological interventions directly targeting the aging process. Pharmacological interventions against aging should be efficacious when started in adults and, ideally, repurpose existing drugs. We show that dramatic lifespan extension can be achieved by targeting multiple, evolutionarily conserved aging pathways and mechanisms using drug combinations. Using this approach in C. elegans, we were able to slow aging and significantly extend healthy lifespan. To identify the mechanism of these drug synergies, we applied transcriptomics and lipidomics analysis. We found that drug interactions involved the TGF-b pathway and recruited genes related with IGF signaling. daf-2, daf-7, and sbp-1 interact upstream of changes in lipid metabolism, resulting in increased monounsaturated fatty acid content and this is required for healthy lifespan extension. These data suggest that combinations of drugs targeting distinct subsets of the aging gene regulatory network can be leveraged to cause synergistic lifespan benefits.

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As multiple research groups around the world race to build a scalable quantum computer, questions remain about how the achievement of quantum supremacy will be verified.

Quantum supremacy is the term that describes a quantum ’s ability to solve a computational task that would be prohibitively difficult for any classical algorithm. It is considered a critical milestone in , but because the very nature of quantum activity defies traditional corroboration, there have been parallel efforts to find a way to prove that quantum supremacy has been achieved.

Researchers at the University of California, Berkeley, have just weighed in by giving a leading practical proposal known as random circuit sampling (RCS) a qualified seal of approval with the weight of complexity theoretic evidence behind it. Random circuit sampling is the technique Google has put forward to prove whether or not it has achieved quantum supremacy with a 72-qubit computer chip called Bristlecone, unveiled earlier this year.

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If a recent project using Google’s DeepMind were a recipe, you would take a pair of AI systems, images of animals, and a whole lot of computing power. Mix it all together, and you’ d get a series of imagined animals dream ed up by one of the AIs. A look through the research paper about the project—or this open Google Folder of images it produced—will likely lead you to agree that the results are a mix of impressive and downright eerie.

But t he eerie factor doesn’t mean the project shouldn’t be considered a success and a step forward for future uses of AI.

From GAN To BigGAN

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