Exercise really does influence how we age, and a new study shows how regular exercise in later life can help offset the decline of NAD+ and NAMPT, two important molecules that facilitate cellular energy production, in skeletal muscle.
NAD+ and mitochondria
The mitochondria are the power stations of the cell and provide the energy that our cells need in order to function. As we age, our mitochondria become increasingly dysfunctional and inefficient, and they produce excessive waste in the form of free radicals, which bounce around the interior of the cell, striking and damaging the cellular machinery within.
The next five years will mark a dramatic enterprise shift toward the edge of networks, where emerging technologies can be harnessed to radically improve user experiences, transform business models, and generate vast revenue opportunities, according to a new book by Fast Future in collaboration with Aruba, a Hewlett Packard Enterprise company.
Opportunity at the Edge: Change, Challenge, and Transformation on the Path to 2025, developed by Fast Future in collaboration with Aruba, reports that edge technologies – those which process and analyze user data where people connect to a network – will revolutionize corporate strategies, create more dynamic, responsive, and personalized customer and employee experiences, enable powerful business and revenue models, and even catalyze the growth of entirely new industries. To unlock these opportunities, the book argues that enterprises must embrace fundamental change, engaging in widespread strategic, structural, and leadership transformation.
Morten Illum, VP EMEA at Aruba, comments: “The findings in this book highlight the vast commercial potential for enterprises utilizing edge technologies, if companies are willing and able to enact the considerable organizational changes needed. The edge represents a dramatic overhaul in how companies understand, service, and meet the needs of their customers and employees. It will be a world defined by dynamic, immediate, and personalized services.”
Key Themes and Findings
Commissioned to explore the scale of possibilities presented by edge technologies in the next 3–5 years, the book features insights from 19 leading global CIOs, technology leaders, industry experts and futurists, and a perspectives survey of 200 future thinkers from across the globe. It explores the edge technologies that are driving change, the use cases and businesses opportunities these are creating, and the ways in which organizations can adapt to take advantage. Key trends that emerged include:
The edge of the network holds the key to industry transformation: The edge is designed to enable and capitalize on modern digital experiences at the convergence of people, apps, and things – allowing customer and ecosystem partners to take these actionable insights to then create “experiences” for employees and customers. This is making it possible for businesses and organizations in various industries to leverage data and insights from the edge to deliver new and immersive experiences to consumers and end customers. It is driving sectors from education and retail to healthcare and hospitality to rethink how they act today. New types of experiences such as location-aware mobile engagement, digitally assisted patient care, and user-aware meeting rooms can give organizations a competitive advantage.
At least one-third of businesses will create edge-enabled mainstream personalization by 2025:
STOP. THINK. REFLECT. S Science has made it abundantly clear that the world around us is an extremely dynamic place, and the secret of our existence – the secret of life itself – is change: All living organisms must either adapt to the changes taking place around them or perish. Science has also…
Physicists have spotted the highest-energy light ever seen. It emanated from the roiling remains left behind when a star exploded.
This light made its way to Earth from the Crab Nebula, a remnant of a stellar explosion, or supernova, about 6,500 light-years away in the Milky Way. The Tibet AS-gamma experiment caught multiple particles of light — or photons — from the nebula with energies higher than 100 trillion electron volts, researchers report in a study accepted in Physical Review Letters. Visible light, for comparison, has just a few electron volts of energy.“This energy regime has not been accessible before,” says astrophysicist Petra Huentemeyer of Michigan Technological University in Houghton, who was not involved with the research. For physicists who study this high-energy light, known as gamma rays, “it’s an exciting time,” she says.
A lil bit of everything from overpopulation to growing interest. Aubrey says a 50% chance in 15 to 20 years but he is planning human trials starting in 2021.
The arrival of such fast weaponry will dangerously compress the time during which military officials and their political leaders — in any country — can figure out the nature of an attack and make reasoned decisions about the wisdom and scope of defensive steps or retaliation. And the threat that hypersonics pose to retaliatory weapons creates what scholars call “use it or lose it” pressures on countries to strike first during a crisis. Experts say that the missiles could upend the grim psychology of Mutual Assured Destruction, the bedrock military doctrine of the nuclear age that argued globe-altering wars would be deterred if the potential combatants always felt certain of their opponents’ devastating response.
The new weapons — which could travel at more than 15 times the speed of sound with terrifying accuracy — threaten to change the nature of warfare.
A Mach 14 Waverider glide vehicle, which takes its name from its ability to generate high lift and ride on its own shock waves. This shape is representative of the type of systems the United States is developing today. Credit Credit Dan Winters for The New York Times.
