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Mar 27, 2019

Plant-based footwear from DuPont Tate & Lyle’s Bio-PDO

Posted by in categories: biotech/medical, food

Bio-PDO — Susterra propanediol produced by DuPont Tate & Lyle Bio Products — are among the many smart applications of corn, and constitute the building blocks of a number of environmentally friendly materials, increasingly used in the footwear manufacture.

We are all familiar with sweetcorn or corn on the cob and many of us enjoy eating it boiled and coated in butter. Americans in particular are especially fond of it although less than 1% of all the corn grown annually in the USA is for human consumption. The remaining 99% is industrial corn or maize which is used for animal feed and for processing into a variety of other products. Among these is Bio-PDO or, to give it its commercial name, Susterra propanediol produced by DuPont Tate & Lyle Bio Products, which is used as a basis for a number of environmentally friendly materials, increasingly used in footwear manufacture.

The variety of corn involved is known as yellow dent and has a high starch content. After harvesting and drying, it is transported to Tate & Lyle’s wet mill at Loudon, Tennessee. Using a wet milling process, the corn is separated into its four basic components: starch, germ, fibre and protein. The nutrient rich components are used for animal feed while glucose is derived from the remaining starch fraction and is the raw material used for making 1.3- propanediol. The process starts off with a culture of a special microorganism in a small flask with the glucose. As it grows, it is transferred to a seed fermenter, followed by a ten-story high production fermenter. Fermentation takes place under exact temperature conditions and involves a patented process where the microorganism functions as a biocatalyst, converting glucose into biobased 1.3-propaneidol.

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Mar 27, 2019

Biotechnology meets fashion and sports performance: Trends in the apparel industry

Posted by in categories: biotech/medical, sustainability

Spiders, mushrooms and algae may help build the next Hilfiger, Levi and Chanel.

Organisms are the great designers of our planet, producing materials in distinct patterns to serve a specific function. Bees produce hexagonal honeycombs to store honey, spiders weave symmetrical webs to capture prey, and nautiluses form a logarithmic spiral shell to protect their insides. Synthetic biologists, ever inspired by nature, are leveraging these unique abilities, harnessing nature’s potential to revolutionize apparel by guiding structural assemblies at the molecular level.

Here are three examples of innovative companies — in Tokyo, New York, and Berkeley — that are letting nature show the way to better, more sustainable materials in a quest to alter the fashion and apparel industries forever.

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Mar 27, 2019

Lasers can send a whispered audio message directly to one person’s ear

Posted by in category: media & arts

Lasers have been used to send targeted, quiet messages to someone from several meters away, in a way that no one nearby would be able to hear.

How it works: To send the messages, researchers from MIT relied upon the photoacoustic effect, in which water vapor in the air absorbs light and forms sound waves. The researchers used a laser beam to transmit a sound at 60 decibels (roughly the volume of background music or conversation in a restaurant) to a target person who was standing 2.5 meters away.

A second technique modulated the power of the laser beam to encode a message, which produced a quieter but clearer result. The team used it to beam music, recorded speech, and various tones, all at conversational volume. “This can work even in relatively dry conditions because there is almost always a little water in the air, especially around people,” team leader Charles M. Wynn said in a press release. Details of the research were published in Optics Letters.

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Mar 27, 2019

Here’s every spacesuit NASA astronauts have worn since the 1960s — and new models that may soon arrive

Posted by in category: space travel

Astronaut spacesuits debuted in the 1960s but continue to evolve as NASA and companies like Boeing and SpaceX push to explore the moon and Mars.

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Mar 27, 2019

Adult hippocampal neurogenesis is abundant in neurologically healthy subjects and drops sharply in patients with Alzheimer’s disease

Posted by in categories: biotech/medical, life extension, neuroscience

https://paper.li/e-1437691924#/ https://www.nature.com/articles/s41591-019-0375-9


The hippocampus is one of the most affected areas in Alzheimer’s disease (AD). Moreover, this structure hosts one of the most unique phenomena of the adult mammalian brain, namely, the addition of new neurons throughout life. This process, called adult hippocampal neurogenesis (AHN), confers an unparalleled degree of plasticity to the entire hippocampal circuitry3,4. Nonetheless, direct evidence of AHN in humans has remained elusive. Thus, determining whether new neurons are continuously incorporated into the human dentate gyrus (DG) during physiological and pathological aging is a crucial question with outstanding therapeutic potential. By combining human brain samples obtained under tightly controlled conditions and state-of-the-art tissue processing methods, we identified thousands of immature neurons in the DG of neurologically healthy human subjects up to the ninth decade of life. These neurons exhibited variable degrees of maturation along differentiation stages of AHN. In sharp contrast, the number and maturation of these neurons progressively declined as AD advanced. These results demonstrate the persistence of AHN during both physiological and pathological aging in humans and provide evidence for impaired neurogenesis as a potentially relevant mechanism underlying memory deficits in AD that might be amenable to novel therapeutic strategies.

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Mar 27, 2019

No sleep, no sex, no life: tech workers in China’s Silicon Valley face burnout before they reach 30

Posted by in categories: internet, sex

The Post spoke to tech workers in Zhongguancun and other parts of Beijing for a snapshot of what life is really like living in China’s Silicon Valley, as these tech hubs – home to internet giants like Baidu, Meituan and ByteDance – have been dubbed.


Life in China’s tech industry is not easy, with young employees and entrepreneurs battling burnout while also worrying about career ceilings and lay-offs.

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Mar 26, 2019

A superposition of possible facts causes quantum conflict

Posted by in category: quantum physics

Measurement of a measurement result leads to a disagreeable answer.

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Mar 26, 2019

100th Missile Defense Brigade

Posted by in category: futurism

🚀🚀💥💥 #FTG11

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Mar 26, 2019

SpaceX proves higher than necessary safety of Starlink constellation

Posted by in categories: internet, satellites

In an electronic filing with the Federal Communications Commission (FCC), SpaceX has demonstrated a higher than necessary safety for their Starlink constellation satellites in terms of collision risk with other objects in orbit in the scenario that a Starlink satellite becomes uncontrollable after launch.

The filing, in response to FCC questions, reveals SpaceX’s upcoming space-based internet project carries a collision risk 2.1 times less likely than the accepted NASA standard.

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Mar 26, 2019

Gene-Editing Record Smashed With Over 13,000 Changes Made to a Single Human Cell

Posted by in categories: biotech/medical, genetics

Using a modified version of CRISPR, a team of geneticists has successfully triggered 13,200 genetic changes to a single human cell. That’s a new record, by a long shot. This sweeping new editing process could eventually be used to strip DNA of useless or dangerous genetic information—or create entirely new kinds of life.

New research uploaded to the preprint bioRxiv server describes the achievement, in which a Harvard University team led by George Church edited the living crap out of a single human cell to the tune of 13,200 total modifications. Incredibly, the cell survived. The previous record for bulk edits made to a single cell was set in 2017, when Church and his colleagues knocked out 62 copies of a retrovirus found in pig genomes. The new achievement is thus “three orders of magnitude greater” than the previous standard, the authors wrote in their paper.

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