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It was a pleasure speaking to Dr. Ronald Kohanski at the 2019 Ending Age-Related Diseases conference. Dr. Kohanski joined the field of aging research in 2005 as a Program Officer for the Division of Aging Biology at the National Institute on Aging. He moved on to become its Deputy Director in 2007 and has held the position ever since. Within aging research, he has focused his efforts on the areas of stem cell and cardiovascular biology.

Besides his work at the NIA, Ronald Kohanski is a co-founder and co-leader of the trans-NIH Geroscience Interest Group (GSIG) with which he has organized several summits to discuss and disseminate the group’s focus. The GSIG directs its attention toward aging as the major risk factor for most chronic age-related diseases, and Dr. Kohanski actively encourages researchers to expand studies beyond laboratory animals. He underwrites the importance of addressing the basic biology of aging explicitly in human and non-laboratory animal populations. He believes that age should be considered a fundamental parameter in research that uses animal models of chronic disease.

Dr. Kohanski was trained in the field of biochemistry. He received his PhD from the University of Chicago in 1981, after which he conducted a postdoctoral fellowship with M. Daniel Lane at the Johns Hopkins University School of Medicine. He held a faculty position at the Mount Sinai School of Medicine for 17 years before returning to Johns Hopkins as a faculty member and researcher in the areas of enzymology and developmental biology of the insulin receptor.

Dr. Qingsong Zhu, the COO of Insilico Medicine, discussed the use of deep learning in creating biomarkers for aging. Initially discussing existing clocks and the problems with animal translation, he went on to discuss what sorts of markers are ideal for age-related research and the details of training and testing a model that works with these markers, showing that a deep model compares favorably to other models.

He also used his model to show that smoking does, in fact, cause accelerated aging.

You can claim to be interested in historical artifacts like pottery, suits of armor, and maybe even a mummy, but the most compelling reason to visit a museum, even as an adult, are the dinosaur fossils. If your hometown happens to be lacking in museums, however, Lego’s new Dinosaur Fossils set puts a small collection of thunder lizard skeletons on your desk, no admission required.

Bio printing footage provided by College of Engineering, and heart valve footage provided by Regenerative Biomaterials Group, Carnegie Mellon University.
https://regenerativebiomaterials.com/

Lulzbot invited us out to showcase the BIO, their OPEN SOURCE 3D printer capable of 3D bioprinting. Materials like unmodified collagen and fetal stem cells! It’s open source, and launches at a price of $7500 USD.

http://www.lulzbot.com/bioprinting

#3dprinting #3dbioprinting #lulzbotbio

NEW YORK, Oct. 16, 2019 – In January 2019, Virgin Galactic Founder Sir Richard Branson and Under Armour CEO and Founder Kevin Plank announced a collaboration which saw Under Armour become Virgin Galactic’s Technical Spacewear Partner. Today, the companies unveiled the collaboratively designed spacewear system for Virgin Galactic astronauts comprising of a base layer, spacesuit, footwear, training suit and Limited Edition astronaut jacket. It is the first such collection ever created specifically for private astronauts.

The design of astronaut apparel is a unique combination of the requirement for comfort and utility matched by the ultimate focus on customer experience. Every element of the Virgin Galactic customer journey is designed to enrich the profound and transformative qualities of the human spaceflight experience. For Virgin Galactic Future Astronauts, that life-changing, personal experience is eagerly anticipated and the newly unveiled spacewear has been specifically designed to support it.

I n August, three graduate students at Carnegie Mellon University were crammed together in a small, windowless basement lab, using a jury-rigged 3D printer frame to zap a slice of mouse brain with electricity.

The brain fragment, cut from the hippocampus, looked like a piece of thinly sliced garlic. It rested on a platform near the center of the contraption. A narrow tube bathed the slice in a solution of salt, glucose, and amino acids. This kept it alive, after a fashion: neurons in the slice continued to fire, allowing the experimenters to gather data. An array of electrodes beneath the slice delivered the electric zaps, while a syringe-like metal probe measured how the neurons reacted. Bright LED lamps illuminated the dish. The setup, to use the lab members’ lingo, was kind of hacky.