Lifeboat Foundation

Proteins are often called the working molecules of the human body. A typical body has more than 20,000 different types of proteins, each of which is involved in many functions essential to human life.

Now, Purdue University researchers have designed a novel approach to use deep learning to better understand how proteins interact in the body – paving the way to producing accurate structure models of protein interactions involved in various diseases and to design better drugs that specifically target protein interactions. The work is released online in Bioinformatics.

“To understand molecular mechanisms of functions of protein complexes, biologists have been using experimental methods such as X-rays and microscopes, but they are time- and resource-intensive efforts,” said Daisuke Kihara, a professor of biological sciences and computer science in Purdue’s College of Science, who leads the research team. “Bioinformatics researchers in our lab and other institutions have been developing computational methods for modeling protein complexes. One big challenge is that a computational method usually generates thousands of models, and choosing the correct one or ranking the models can be difficult.”

Guardian of the Amazon! — Come hear the recent ideaXme (http://radioideaxme.com/) episode where we are joined by Ms. Nemonte Nenquimo, President of the Waorani Pastaza Organization, CONCONAWEP (Coordinating Council of the Waorani Nationality of Ecuador), following their recent landmark legal victory against the Ecuadorian government, leading to 500,000 acres of Amazon rainforest protected from oil drilling and timber companies (English voice over — Spanish audio link to be posted soon) — #Ideaxme #Amazon #Rainforest #Jungle #Ecuador #Waorani #Huaorani #Amerindian #Environment #Trees #Herbal #EthnoMedicine #Sustainability #Ayahuasca #ClimateChange #GretaThunberg #Health #Wellness #Longevity #Aging #IraPastor #Bioquark #Regenerage

Ira Pastor, ideaXme exponential health ambassador, interviews Ms. Nemonte Nenquimo, President of the Waorani Pastaza Organization (CONCONAWEP — Coordinating Council of the Waorani Nationality of Ecuador). This is an English language voice over of Ms Nenquimo’s audio interview.

Continue reading “Guardian of The Amazon: Ms Nenquimo protects environment and health for her people and the world” »

For the moment, massive job losses from automation and artificial intelligence are a largely theoretical worry. But tax economists and lawyers are thinking through the economic circumstances in which robot taxes might make sense and the tricky legal decisions and definitions needed to implement them.

A debate is heating up over whether businesses should pay up when they replace human workers with machines.

A new study suggests that human neurons may have more computing power than once thought.

Neon burst onto the scene at CES 2020 in a flurry of hype, but not much understanding of what the company wants to eventually achieve. It’s a complex vision of the future, where we live alongside digital humans that look like us, move like us, and can think, learn, and remember.

Live coverage of SpaceX’s preparations for the next Falcon 9 rocket launch from pad 39A at NASA’s Kennedy Space Center in Florida. The mission will loft an unpiloted Crew Dragon spacecraft on a high-altitude test of the capsule’s launch abort system. Text updates will appear automatically below. Follow us on Twitter.

Scientists at Rutgers University-Newark have discovered that when a key protein needed to generate new brain cells during prenatal and early childhood development is missing, part of the brain goes haywire—causing an imbalance in its circuitry that can lead to long-term cognitive and movement behaviors characteristic of autism spectrum disorder.

“During brain development, there is a coordinated series of events that have to occur at the right time and the right place in order to establish the appropriate number of cells with the right connections,” said Juan Pablo Zanin, Rutgers-Newark research associate and lead author on a paper published in the Journal of Neuroscience.” Each of these steps is carefully regulated and if any of these steps are not regulated correctly, this can impact behavior.”

Zanin has been working with Wilma Friedman, professor of cellular neurobiology in the Department of Biological Sciences, studying the p75NTR protein—needed to regulate cell division—to determine its exact function in brain development, gain a better understanding of how this genetic mutation could cause brain cells to die off and discover whether there is a genetic link to autism or neurological diseases like Alzheimer’s.