New longitudinal research shows that Alzheimer’s disease blood biomarkers rise up to 95 percent faster in people with obesity than in those without.
“Brain rot is not really rotting our brains,” says Earl Miller, a cognitive neuroscientist at Massachusetts Institute of Technology. “It’s constantly creating an environment that our brains are not equipped to deal with—that’s the real problem.
From analog hobbies to tech curfews, these Gen Zers are experimenting with science-backed ways to help their brains feel a little less foggy.
The bumpy trajectory of human aging may have a tipping point as we enter our twilight years, a new study has found.
Past the age of around 75, our bodies can no longer easily recover from injury or illness – a sharp decline in resilience that comes with a corresponding rise in the risk of dying, according to researchers at Dalhousie University in Canada.
Their model looks at aging as a balance between damage and repair, with the breakdown of that balance marking the point of no return into frailty.
Discover the 15 most advanced alien races ever imagined in science fiction—from reality-bending cosmic civilizations to hyper-intelligent species capable of rewriting the laws of physics.
In this video, we explore how these alien races evolved, the technologies they command, and why they stand above all others in the sci-fi universe. Whether you’re into Star Wars, Star Trek, Marvel, DC, Mass Effect, Stargate, Halo, or classic literature, this countdown covers the most iconic and most powerful extraterrestrial species ever written.
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When thinking, the human brain performs a true masterpiece of information processing: around 100 billion neurons communicate with each other via approximately 100 trillion connections. An international team of researchers has discovered that the mechanical properties of the developing brain influence both synapse formation and the emergence of electrical signals. The findings could open up new approaches to understanding neurodevelopmental disorders.
In the brain, highly specific connections called synapses link nerve cells and transmit electrical signals in a targeted manner. Despite decades of research, how synapses form during brain development is still not fully understood. Now, an international research team has discovered that the mechanical properties of the brain play a significant role in this developmental process. In a study recently published in Nature Communications, the scientists showed how the ability of neurons to detect stiffness is related to molecular mechanisms that regulate neuronal development.
The developing brain is generally very soft, like cream cheese, but its stiffness varies across regions. In African clawed frog (Xenopus laevis) embryos, the researchers found that softer regions exhibit higher synapse densities, while stiffer regions show lower densities.
Abstract The review examines modern advances in the genetics of aging and life span. The key molecular mechanisms regulating aging processes at the genetic level are analyzed, including signaling pathways and longevity genes identified in studies on model organisms and through genome analysis of long-lived species. Special attention is given to the insulin/IGF-1 signaling pathway, the role of the FOXO transcription factor, DNA repair systems, epigenetic regulation, and modulation of mTOR and AMPK kinase activity. Results of experimental studies on increasing the life span of model organisms through genetic manipulations and combined approaches are presented.