Lifeboat Foundation

Once you hit a certain age you start to see subtle changes and many begin to search for options to hold onto the appearance of youthfulness for as long as they can in the form of lotions, potions, creams, supplements, serums, diets, and concoctions among others.

Soon there may be a new addition to the anti-aging lineup, that being rapamycin which is an FDA approved drug that is normally used to prevent organ rejection after transplant, the drug may also be helpful in slowing in aging skin according to a recent study published in Geroscience.

Studies have used rapamycin to effectively slow aging in worms, flies, and mice but this study from Drexel University College of Medicine is the first to show an effect on aging in human tissues, specifically the skin; findings showed signs of aging to be reduced including decreases in wrinkles, reduced sagging, and more even skin tone when delivered to humans topically.

UConn engineers have designed a non-toxic, biodegradable device that can help medication move from blood vessels into brain tissues —a route traditionally blocked by the body’s defense mechanisms. They describe their invention in the 23 December issue of PNAS.

Blood vessels in the brain are lined by cells fitted together tightly, forming a so-called blood-brain barrier, which walls off bacteria and toxins from the brain itself. But that blood-brain barrier also blocks medication for brain diseases such as cancer.

“A safe and effective way to open that barrier is ultrasound,” says Thanh Nguyen, a biomedical engineer at UConn. Ultrasonic waves, focused in the right place, can vibrate the cells lining blood vessels enough to open transient cracks in the blood-brain barrier large enough for medication to slip through. But the current ultrasound technology to do this requires multiple ultrasound sources arrayed around a person’s skull, and then using an MRI machine to guide the person operating the ultrasounds to focus the waves in just the right place. It’s bulky, difficult, and expensive to do every time a person needs a dose of medication.

So what is dark matter, anyway? Why can’t scientists get enough of the stuff, even though they can’t actually find it? What deep, dark secrets does it hold? And could it ultimately shape the future of life as we know it?

Making great strides isn’t the same as answering astrobiology’s fundamental questions. Here’s a quick reality check on the state of the field.

Taxiing in a circle might make you dizzy, though.

Physicist Tor Raubenheimer explores the world by climbing rocks and designing particle accelerators.

Let’s be clear.

What can we trust? Why is the ‘information ecology’ so damaged, and what would it take to make it healthy?

Continue reading “The War on Sensemaking, Daniel Schmachtenberger” »

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Holochain is a next generation protocol and an evolution of blockchain for web 3.0 leading to a more distributed world.

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