Lifeboat Foundation

Venture capitalist Chamath Palihapitiya stunned CNBC anchor Scott Wapner and generated widespread applause on social media by declaring in a television interview Thursday that the U.S. government should let hedge funds and billionaire CEOs “get wiped out” by the coronavirus-induced economic collapse and instead focus its attention on rescuing Main Street.

When Wapner, seemingly incredulous at what he was hearing, asked Palihapitiya why he would support the collapse of large companies, the Social Capital CEO said “this is a lie that’s been purported by Wall Street.”

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The Harvard University offshoot i20 Therapeutics is setting the goal of one day having those who suffer from diabetes to be able to treat it with pills rather than injections with a syringe when they need to take their medications.

Bioengineering researchers began to publish their methods in 2018 for turning liquid medications into encapsulated easy to swallow forms, which has demonstrated some early success with insulin in animal models.

Starting out with $4 million in seed money from Sanofi Ventures and the Juvenile Diabetes Research Foundation’s T1D Fund, i20 Therapeutics plans to take that technology to GLP1 analogs, these are the glucagon like peptides that help to maintain blood sugar levels; i20 is focused on creating the next generation of oral peptide and protein based therapies.

A drug used for cancer therapy has shown promise in reversing kidney damage caused by systemic lupus erythematosus (SLE, or lupus), according to a Yale-led study published April 8 in the journal Science Translational Medicine.

“Kidney damage affects about half of the patients with lupus, sometimes leading to renal failure with a requirement for dialysis or transplantation,” said Joe Craft, the Paul B. Beeson Professor of Medicine (rheumatology) and professor of immunobiology. “Finding what causes that damage is extremely important.”

Lupus is an autoimmune disease in which immune cells attack tissues in the body of the host, with kidneys being particularly susceptible in a condition called lupus nephritis. In lupus nephritis, the patient’s own T cells infiltrate kidney tissue and trigger a decrease in oxygen, leading to tissue damage and potentially end-stage kidney disease.

Researchers from North Carolina State University have developed an “off-the-shelf” artificial cardiac patch that can deliver cardiac cell-derived healing factors directly to the site of heart attack injury. In a rat model of heart attack, the freezable, cell-free patch improved recovery. The researchers also found similar effects in a pilot study involving a pig model of heart attack.

Cardiac patches are being studied as a promising future option for delivering cell therapy directly to the site of heart attack injury. However, current cardiac patches are fragile, costly, time-consuming to prepare and, since they use live cellular material, increase risks of tumor formation and arrhythmia.

“We have developed an artificial cardiac patch that can potentially solve the problems associated with using live cells, yet still deliver effective cell therapy to the site of injury,” says Ke Cheng, Randall B. Terry, Jr. Distinguished Professor in Regenerative Medicine at NC State’s College of Veterinary Medicine and professor in the NC State/UNC Joint Department of Biomedical Engineering.

A team of University of Florida engineers developed a cheap and easily sourced ventilator made with PVC, sprinkler valves, and Arduino. The design can be made for around $125 and could help with the demand for ventilators in the COVID-19 pandemic.

A ventilator envisioned by a University of Florida engineer and built with do-it-yourself parts gained first-step FDA authorization this week, offering hope that it could be in use within weeks at hospitals around the world where COVID-19 patients have overwhelmed supplies of traditional medical equipment.

The ventilator, composed of parts readily available for less than $250, can be assembled in less than an hour. UF has made plans and software available free over the internet.

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Researchers at the University of North Carolina at Chapel Hill made a one-way street for electrons that may unlock the ability for devices to process ultra-high-speed wireless data and simultaneously harvest energy for power. The researchers did this by shaping silicon on a microscopic scale to create a funnel, or “ratchet,” for electrons.

This method overcomes the speed limitations of prior technologies by removing interfaces that tend to slow down devices.” This work is exciting because it could enable a future where things like low-power smartwatches are wirelessly charged from the data they already receive without ever needing to a leave a person’s wrist,” said James Custer Jr., a doctoral student in UNC-Chapel Hill’s College of Arts & Sciences.

The findings were published April 10 in the journal Science. Custer is lead author. He worked with collaborators at Duke and Vanderbilt universities.

How can we promote the creation of new neurons — and why is it so important?

To commemorate the 50th anniversary of the Apollo 13 mission, a panoramic high-definition image of astronaut Fred Haise napping in the “lifeboat” Lunar Module has been produced.

Raw footage of HEV demonstrator. Particle physicists propose stripped-down ventilator to help combat COVID-19.