John Horton Conway, a legendary mathematician who stood out for his love of games and for bringing mathematics to the masses, died on Saturday, April 11, in New Brunswick, New Jersey, from complications related to COVID-19. He was 82.
Known for his unbounded curiosity and enthusiasm for subjects far beyond mathematics, Conway was a beloved figure in the hallways of Princeton’s mathematics building and at the Small World coffee shop on Nassau Street, where he engaged with students, faculty and mathematical hobbyists with equal interest.
Conway, who joined the faculty in 1987, was the John von Neumann Professor in Applied and Computational Mathematics and a professor of mathematics until 2013 when he transferred to emeritus status.
How and when will this pandemic end? We asked a virologist: https://bit.ly/3afDiMy from World Economic Forum P.S., Many people predict that life will be permanently changed after COVID-19 pandemic. Some new things will become the norm, such as remote working, #telemedicine, the increase of #automation, online education, and so on (e.g., https://bit.ly/2z6qF9I). Our opinion is that “whether the above things become permanent depends on how the pandemic ends.” If the virus becomes seasonal, as predicted by the virologist in the interview, then our lives may gradually shift towards these new practices (i.e., working remotely, seeing doctor remotely, and learning online, etc.). However, if the virus disappears abruptly, just like the 1918 Spanish flu (https://bit.ly/3bdJKop), our lives may slowly go back to what we used to know before the COVID-19 crisis.
We spoke to Belgian virologist Guido Vanham, the former head of virology at the Institute for Tropical Medicine in Antwerp, Belgium, and asked him: how will this pandemic end? And on which factors might that depend?
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Could we reverse epigenetic aging by re-growing the thymus? In the future, will it be possible to extend our lives or increase our longevity? Dr. Greg Fahy is a low-temperature biologist and investigator of aging intervention in humans. His first clinical trial, intended to reverse immune system aging, provided evidence that aging could be reversed in humans. Dr. Greg Fahy is a low-temperature biologist and investigator of aging intervention in humans. His first clinical trial, intended to reverse immune system aging, provided the first evidence that global aging can be reversed in humans. This talk was given at a TEDx event using the TED conference format but independently organized by a local community.
The ongoing outbreak of the novel coronavirus disease (COVID-19) has spread globally and poses a threat to public health in more than 200 countries. Reliable laboratory diagnosis of the disease has been one of the foremost priorities for promoting public health interventions. The routinely used reverse transcription polymerase chain reaction (RT-PCR) is currently the reference method for COVID-19 diagnosis. However, it also reported a number of false-positive or –negative cases, especially in the early stages of the novel virus outbreak. In this work, a dual-functional plasmonic biosensor combining the plasmonic photothermal (PPT) effect and localized surface plasmon resonance (LSPR) sensing transduction provides an alternative and promising solution for the clinical COVID-19 diagnosis. The two-dimensional gold nanoislands (AuNIs) functionalized with complementary DNA receptors can perform a sensitive detection of the selected sequences from severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) through nucleic acid hybridization. For better sensing performance, the thermoplasmonic heat is generated on the same AuNIs chip when illuminated at their plasmonic resonance frequency. The localized PPT heat is capable to elevate the in situ hybridization temperature and facilitate the accurate discrimination of two similar gene sequences. Our dual-functional LSPR biosensor exhibits a high sensitivity toward the selected SARS-CoV-2 sequences with a lower detection limit down to the concentration of 0.22 pM and allows precise detection of the specific target in a multigene mixture. This study gains insight into the thermoplasmonic enhancement and its applicability in the nucleic acid tests and viral disease diagnosis.
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An illustration of Kepler-1649c orbiting around its host red dwarf star. This newly discovered exoplanet is in its star’s habitable zone and is the closest to Earth in size and temperature found yet in Kepler’s data. Credits: NASA/Ames Research Center/Daniel Rutter
A team of transatlantic scientists, using reanalyzed data from National Aeronautics and Space Administration’s Kepler space telescope, has discovered an Earth-sized exoplanet orbiting in its star’s habitable zone, the area around a star where a rocky planet could support liquid water.
Scientists discovered this planet, called Kepler-1649c, when looking through old observations from Kepler, which the agency retired in 2018. While previous searches with a computer algorithm misidentified it, researchers reviewing Kepler data took a second look at the signature and recognized it as a planet. Out of all the exoplanets found by Kepler, this distant world – located 300 light-years from Earth – is most similar to Earth in size and estimated temperature.
A comparison of Earth and Kepler-1649c, an exoplanet only 1.06 times Earth’s radius Credits: NASA/Ames Research Center/Daniel Rutter
This newly revealed world is only 1.06 times larger than our own planet. Also, the amount of starlight it receives from its host star is 75% of the amount of light Earth receives from our Sun – meaning the exoplanet’s temperature may be similar to our planet’s, as well. But unlike Earth, it orbits a red dwarf. Though none have been observed in this system, this type of star is known for stellar flare-ups that may make a planet’s environment challenging for any potential life.
“This intriguing, distant world gives us even greater hope that a second Earth lies among the stars, waiting to be found,” said Thomas Zurbuchen, associate administrator of NASA’s Science Mission Directorate in Washington. “The data gathered by missions like Kepler and our Transiting Exoplanet Survey Satellite (TESS) will continue to yield amazing discoveries as the science community refines its abilities to look for promising planets year after year.”
