This large cohort study showed that higher serum CXCL9 was associated with greater burden of white matter disease in the brain, independent of vascular risk factors, renal function, and genetic predisposition, supporting a role for CXCL9 in white matter pathogenesis.
In this umbrella review of 60 meta-analyses of 1751 RCTs, GLP-1 RAs were associated increased GI adverse events (eg, nausea/vomiting); suggested protective associations with respiratory diseases and serious infections require further confirmation.
This meta-analysis evaluates the reported outcomes of glucagon-like peptide-1 (GLP-1) receptor agonists beyond glycemic control, weight management, and cardiorenal protection and assesses the credibility of the evidence.
Individual variability in synaptic gene expression and synapse density in induced pluripotent stem cell–derived neurons predicted macro-scale alterations in gray matter volume and gamma-band activity in patients with Schizophrenia.
SIRS2026.
This genetic association study tests whether genetically driven variability in excitatory neurons’ transcriptome and synapse density in patient-derived neurons in vitro explain individual changes in cortical morphology, electrophysiology, and cognitive impairments in vivo.
Periodontitis is a serious chronic inflammatory form of gum disease that affects millions worldwide. It can lead to tooth loss and the destruction of supporting bone. This disease has also been linked to other health problems, including diabetes, respiratory infections, and heart disease, impacting quality of life and increasing health care costs.
Current treatments target bacterial infection and inflammation through nonsurgical therapies, such as scaling and root planing, commonly known as “deep cleaning.” However, they do not repair the gum’s extracellular matrix (ECM), the gingival tissue’s structural support that is damaged by chronic inflammation. Without this foundation, gingival tissue cannot function properly, allowing inflammation to persist and slowing healing.
Now, new research led by Kyle H. Vining and Hardik Makkar of the School of Dental Medicine demonstrates how the physical properties of the gingival tissue impact periodontal health and disease. Their findings are published in Advanced Materials.
Watch live here!! Artemis II, NASA’s first crewed Moon mission in over 50 years, will launch astronauts around the Moon aboard the Orion spacecraft using the powerful SLS rocket. This historic NASA lunar mission will test deep-space life-support systems, high-speed Earth reentry, and the next phase of the Artemis program leading to the Artemis III Moon landing. The Artemis 2 crew—Reid Wiseman, Victor Glover, Christina Koch, and Jeremy Hansen—will travel farther from Earth than any humans in decades, performing a lunar flyby, systems checkout, and deep-space trajectory critical for future Moon to Mars exploration. This mission is a major milestone for NASA Artemis, lunar exploration, Moon mission timeline, and the return of humans to the lunar surface. Space fans are watching for updates on Artemis II launch date, SLS rocket tests, Orion spacecraft performance, and NASA livestream coverage. Artemis II is the flagship NASA Artemis mission that will send the Artemis 2 crew of four Artemis II astronauts on a historic crewed lunar mission aboard the Orion spacecraft, launched by NASA’s powerful SLS rocket. This mission includes a precise lunar flyby and marks a major milestone in the Artemis program, advancing NASA’s long-term Moon to Mars strategy. As part of the modern NASA Moon mission campaign, Artemis II will test deep-space systems critical for future lunar exploration, including the planned Artemis 3 Moon landing. Space fans tracking the Moon mission timeline are watching closely for the official Artemis 2 launch date, major NASA spaceflight updates, and the upcoming NASA livestream. Expect major space news 2025 announcements as NASA releases each Moon mission update and continues preparing for humanity’s return—returning to the Moon for the first time in more than 50 years. Artemis Launch Live: Everything You Need to Know About NASA’s Return to the Moon. The Artemis launch live event marks one of the most anticipated moments in modern spaceflight, as NASA prepares for a historic rocket launch today live from Kennedy Space Center Florida. This mission to the moon 2026 is part of the broader Artemis program, designed to return humans to the Moon for the first time since Apollo 17, the last moon mission in 1972.
The Artemis 2 mission is NASA’s first crewed flight in the Artemis program, following the success of Artemis 1 launch. Unlike earlier missions, Artemis II will not land on the moon, but instead will send astronauts aboard the Orion capsule on a deep-space journey around the Moon.
Where to watch Artemis launch. How to watch the Artemis 2 launch. Watch Artemis II launch live. YouTube Artemis launch. Artemis 2 Crew and Astronauts.
Artemis 2 flight path and timeline.
The Artemis II flight path will take the spacecraft around the Moon and back to Earth.
Background and ObjectivesMultiple sclerosis (MS) is a chronic progressive, demyelinating autoimmune CNS disease. Autoantibodies to the motif P-(SA)-x-(SGA)-R-(SN)-(LRKH) are a class of predictive markers specific to MS that could add to emerging…