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How Real Is The Expanse’s Fusion Drive? | SciFi Explained

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I thought it was about time that we got excited by some clever use of science in fiction. We may not be able to build a Rocinante tomorrow but all the elements are based on real science that we have been able to demonstrate.
No breaking the laws of physics here!! A fairly unique thing for this channel.

Keep an eye out for the shorts series which will go into a bit more detail on some of these topics. And if you want to know more about fission based propulsion then join the nerd club through YouTube memberships or on Patreon.

Thanks for watching, stay nerdy!

Chapters:
00:00 — The best science in fiction.
04:20 — Solomons test flight.
06:42 — It is rocket science!
10:26 — Nuclear reactions.
16:47 — Fusion.
21:00 — The challenges.
25:47 — Is anyone building it?

AI learns to perform analog layout design

Researchers at Pohang University of Science and Technology (POSTECH) have developed an artificial intelligence approach that addresses a key bottleneck in analog semiconductor layout design, a process that has traditionally depended heavily on engineers’ experience. The work was recently published in the journal IEEE Transactions on Circuits and Systems I: Regular Papers.

Semiconductors are used in a wide range of technologies, including smartphones, vehicles, and AI servers. However, analog layout design remains difficult to automate because designers must manually arrange structures that determine performance and reliability while meeting a large number of design rules.

Automation has been especially challenging in analog design because layouts are too complex and design strategies differ significantly by circuit. In addition, training data is scarce, since layout data is typically treated as proprietary and is rarely shared outside companies.

Alien Mathematics

Aliens will make use of paraconsistent logic.

Is math truly universal—or just human? Explore how alien minds might think, count, and reason in ways we don’t recognize as mathematics at all.

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Watch my exclusive video The Future of Interstellar Communication: https://nebula.tv/videos/isaacarthur–… out Joe Scott’s Oldest & Newest: https://nebula.tv/videos/joescott-old… 🚀 Join this channel to get access to perks: / @isaacarthursfia 🛒 SFIA Merchandise: https://isaac-arthur-shop.fourthwall… 🌐 Visit our Website: http://www.isaacarthur.net 🎬 Join Nebula: https://go.nebula.tv/isaacarthur ❤️ Support us on Patreon: / isaacarthur ⭐ Support us on Subscribestar: https://www.subscribestar.com/isaac-a… 👥 Facebook Group: / 1,583,992,725,237,264 📣 Reddit Community: / isaacarthur 🐦 Follow on Twitter / X: / isaac_a_arthur 💬 SFIA Discord Server: / discord Credits: Alien Mathematics Written, Produced & Narrated by: Isaac Arthur Select imagery/video supplied by Getty Images Music by Epidemic Sound: http://nebula.tv/epidemic & Stellardrone Chapters 0:00 Intro 2:02 Why We Expect Mathematics to Be Universal 6:32 Math Is Not the Same Even for Humans 10:47 How Alien Biology Could Reshape Their Mathematics 16:44 Alien Logic: When the Rules Themselves Don’t Match 20:37 Oldest & Newest 21:41 Can We Ever Bridge the Mathematical Gap?
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Antibody modulation of B cell responses—Incorporating positive and negative feedback

Antibodies modulate ongoing and future B cell responses. Cyster and Wilson review the various mechanisms whereby antibody feedback shapes B cell responses and present a framework for conceptualizing the ways antigen-specific antibody may influence immunity in conditions as diverse as infectious disease, autoimmunity, and cancer.

Toward regenerative bioprinting: Magnetic mixer enables scalable manufacturing of 3D-printed tissues

3D bioprinting, in which living tissues are printed with cells mixed into soft hydrogels, or “bio-inks,” is widely used in the field of bioengineering for modeling or replacing the tissues in our bodies. The print quality and reproducibility of tissues, however, can face challenges. One of the most significant challenges is created simply by gravity—cells naturally sink to the bottom of the bioink-extruding printer syringe because the cells are heavier than the hydrogel around them.

“This cell settling, which becomes worse during the long print sessions required to print large tissues, leads to clogged nozzles, uneven cell distribution, and inconsistencies between printed tissues,” explains Ritu Raman, the Eugene Bell Career Development Professor of Tissue Engineering and assistant professor of mechanical engineering at MIT.

“Existing solutions, such as manually stirring bioinks before loading them into the printer, or using passive mixers, cannot maintain uniformity once printing begins.”

Smartwatch and Hypertension Notification

From JAMA: The US Food and Drug Administration recently cleared the Apple Watch hypertension notification feature.

Researchers applied performance metrics reported by Apple to nationally representative survey data and found that, overall, 69% of individuals who receive a smartwatch alert would have hypertension, while 79% of those who do not receive an alert would not have hypertension. However, these rates vary according to subgroup characteristics, such as age and sex.

Current guidelines recommend cuff-based blood pressure measurement as the standard for diagnosing hypertension. Incorporating cuffless device technologies into public health screening efforts will require additional validation and careful attention to device accuracy to reduce misclassification and the risk of false reassurance.

This cross-sectional study assesses the potential impact of a smartwatch hypertension notification feature for US adults who have not been diagnosed with hypertension.

Monitoring biological effects of somatic cell genome editing

CRISPR-based genome editing therapeutics are entering the clinic, but in vitro and in vivo tools are needed to assess their safety and efficacy. The authors review complementary technologies to monitor the biological effects of genome editing across scales, including the direct measurement of editing outcomes in DNA, human microphysiological systems and non-invasive in vivo imaging.

A Deep Dive Into The ‘Longevity Vitamin’, Ergothionine

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Photonic processor could streamline 6G wireless signal processing

One of the biggest challenges the researchers faced when designing MAFT-ONN was determining how to map the machine-learning computations to the optical hardware.

“We couldn’t just take a normal machine-learning framework off the shelf and use it. We had to customize it to fit the hardware and figure out how to exploit the physics so it would perform the computations we wanted it to,” Davis says.

When they tested their architecture on signal classification in simulations, the optical neural network achieved 85 percent accuracy in a single shot, which can quickly converge to more than 99 percent accuracy using multiple measurements. MAFT-ONN only required about 120 nanoseconds to perform entire process.

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