Lifeboat Foundation

What exactly is Obesity?

Obesity is known to cause cardiometabolic diseases like hypertension and diabetes but attributing these diseases to merely an overabundance of fat is a simplification. On a basic level, fat acts as a receptacle to store energy, but upon a closer look it is an essential actor in vital bodily processes like the immune response, the regulation of insulin sensitivity, and maintenance of body temperature. In a review published in the journal Cell on February 3rd, 2022, researchers argue that the negative health effects of obesity stem not simply from an excess of fat but from the decline in its ability to respond to changes, or in other words, its plasticity.

The makeup and functioning of this tissue changes in response to weight fluctuations and aging. As fat declines in plasticity due to aging and obesity, it loses its ability to respond to bodily cues. In the current model of this phenomenon, the rapid growth of adipose tissue outpaces its blood supply, depriving the fat cells of oxygen and causing the accumulation of cells that no longer divide. This leads to insulin resistance, inflammation, and cell death accompanied by the uncontrolled spill of lipids from these cells.

Continue reading “New Research Finds That With Obesity, the Problem Isn’t an Excess of Fat but Its Loss of Function” »

Large blocks of genes conserved through hundreds of millions of years of evolution hint at how the first animal chromosomes came to be.

New South Wales has again received an overwhelming response from aspiring developers of wind, solar and storage projects, with more than 34GW of proposals for the South-West Renewable Energy Zone, more than 10 times its likely capacity.

The state government, through its newly formed Energy Corporation of NSW, ran a registration of interest process in October and November for the south-west region, one of at least five REZs planned to help replace the ageing coal fleet over the coming decade.

“There were 49 registrations totalling over 34 gigawatts from potential generation and storage projects – thirteen times the intended capacity for the South-West REZ, which will be no less than 2.5 gigawatts,” James Hay, the CEO of Energy Corp, said in a statement on Friday.

An international study involving researchers from CNRS and CEA as well as the company Kayrros reveals hundreds of major methane leaks linked to the global exploitation of oil and gas. Scientists show that their mitigation would lead to climatic and economic benefits amounting to billions of dollars for the main hydrocarbon producing countries. This work is published on February 4, 2022 in the journal Science.

Original press release published on CEA.

A major contributor to climate change, methane (CH ₄) has a warming potential over 100 years approximately 30 times greater than that of CO ₂. A quarter of anthropogenic emissions of this greenhouse gas come from the global exploitation of coal, oil and natural gas, of which CH₄ is the main component. In 2018, a study had already exposed, based on the case of the United States, the vast underestimation in official inventories of emissions related to the extraction and distribution of oil and gas. A discrepancy which could be explained by sporadic undeclared releases of large quantities of methane by operators in the sector.

Hiding human biases in model biases doesn’t eliminate them or magically make these biases objective. We must adopt a more realistic view.

This is some send-off.

NASA recently announced plans to retire the International Space Station by crashing it into the Pacific Ocean — a spacecraft graveyard.

A Southwest Research Institute scientist measured the properties of ice-brine mixtures as cold as-145 degrees Fahrenheit to help confirm that salty water likely exists between grains of ice or sediment under the ice cap at Mars ’ south pole. Laboratory measurements conducted by SwRI geophysicist Dr. David Stillman support oddly bright reflections detected by the MARSIS subsurface sounding radar aboard ESA’s Mars Express orbiter.

With a 130-foot antenna, MARSIS flies over the planet, bouncing radio waves over a selected area and then receiving and analyzing the echoes or reflections. Any near-surface liquid water should send a strong bright signal, whereas the radar signal for ice and rock would be much smaller.

Because conventional models assume the Mars south polar cap experiences temperatures much lower than the melting point of water, many scientists have questioned the presence of liquid water. Clay, hydrated salts, and saline ices have been proposed as potential explanations for the source of the bright basal reflections. The Italian-led team investigating the proposed phenomena used previously published data, simulations, and new laboratory measurements.

Neuralink, the startup cofounded and run by Elon Musk that hopes to implant computer chips in people’s brains, may have misled federal securities regulators about the billionaire entrepreneur’s role at the company.

That’s according to government documents and Fortune interviews with securities lawyers and a half-dozen former employees of the company. The employees mostly spoke anonymously out of concern for violating nondisclosure agreements and possible retaliation from Musk.

The episode involves a 2018 letter in which an attorney representing Neuralink downplayed Musk’s leadership role at the company in a letter to the Securities and Exchange Commission. The attorney’s characterization contradicts former employees’ accounts, which depict Musk as very much in charge. Neuralink and the attorney involved in the filing did not respond to requests for comment. lawyer for Neuralink told the SEC that Musk had “no executive or management role” at the company. Former employees say that’s far from the truth.

The world’s first 3D-printed house made from dirt is environmentally friendly and looks great.