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‘Concerning’ CT scans may cause unnecessary hospitalization for some pulmonary embolism patients

Of approximately 250,000 Americans diagnosed with acute pulmonary embolism (PE) in emergency departments each year, most are hospitalized.

But new Michigan Medicine research, published in JAMA Network Open, finds that some patients with PE, a blood clot in one or more , may be hospitalized unnecessarily due to computed tomography (CT) imaging results rather than clinical risk factors.

Approximately 40% of the patients in the study had low-risk , as defined by the Pulmonary Embolism Severity Index, or PESI score. Roughly half of the low risk patients had CT imaging features that physicians consider “concerning,” and these patients fared just as well in the hospital as those whose CT scans showed no concerning findings.

Mint DIS 2023

Generative artificial intelligence (AI) has put AI in the hands of people, and those who don’t use it could struggle to keep their jobs in future, Jaspreet Bindra, Founder and MD, Tech Whisperer Lt. UK, surmised at the Mint Digital Innovation Summit on June 9.

“We never think about electricity until it’s not there. That’s how AI used to be. It was always in the background and we never thought about it. With generative AI it has come into our hands, and 200–300 million of us are like, wow!” said Bindra.

He noted that while AI won’t replace humans at their jobs, someone using AI very well could. He urged working professionals to “recalibrate” and embrace generative AI as a “powerful tool” created by humans, instead of looking at it as a threat.

ChatGPT AI Shines in Challenging Medical Cases

Summary: A novel study put the diagnostic prowess of generative AI, specifically the chatbot GPT-4, to the test, yielding promising results.

The study involved evaluating the AI’s diagnostic accuracy in handling complex medical cases, with GPT-4 correctly identifying the top diagnosis nearly 40% of the time and including the correct diagnosis in its list of potential diagnoses in 64% of challenging cases.

The success of AI in this study could provide new insights into its potential applications in clinical settings. However, more research is needed to address the benefits, optimal use, and limitations of such technology.

Keith Ward — Why is Consciousness so Mysterious?

How can the mindless microscopic particles that compose our brains ‘experience’ the setting sun, the Mozart Requiem, and romantic love? How can sparks of brain electricity and flows of brain chemicals literally be these felt experiences or be ‘about’ things that have external meaning? How can consciousness be explained?

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Keith Ward is a British philosopher, theologian, pastor and scholar. He is a Fellow of the British Academy and (since 1972) an ordained priest of the Church of England. He was a canon of Christ Church, Oxford until 2003. Comparative theology and the relationship between science and religion are two of his main topics of interest.

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Quantum interference of light: Anomalous phenomenon found

A counterintuitive facet of the physics of photon interference has been uncovered by three researchers of Université libre de Bruxelles, Belgium. In an article published this month in Nature Photonics, they have proposed a thought experiment that utterly contradicts common knowledge on the so-called bunching property of photons. The observation of this anomalous bunching effect seems to be within reach of today’s photonic technologies and, if achieved, would strongly impact on our understanding of multiparticle quantum interferences.

One of the cornerstones of quantum physics is Niels Bohr’s complementarity principle, which, roughly speaking, states that objects may behave either like particles or like waves. These two mutually exclusive descriptions are well illustrated in the iconic , where particles are impinging on a plate containing two slits. If the trajectory of each particle is not watched, one observes wave-like interference fringes when collecting the particles after going through the slits. But if the trajectories are watched, then the fringes disappear and everything happens as if we were dealing with particle-like balls in a .

As coined by physicist Richard Feynman, the interference fringes originate from the absence of “which-path” information, so that the fringes must necessarily vanish as soon as the experiment allows us to learn that each particle has taken one or the other path through the left or right slit.

Transformer-based aging clock provides insights into aging

Clinical stage generative AI-driven drug discovery company Insilico Medicine has today published a paper on a new multimodal transformer-based aging clock; the new clock is capable of processing diverse data sets and providing insights into biomarkers for aging, mapping them to genes relevant to both aging and disease, and discovering new therapeutic targets to slow or reverse both aging and aging-related diseases.

Insilico calls the aging clock Precious1GPT, in a nod to the powerful “One Ring” in Tolkien’s Lord of the Rings; the findings have been published in the journal Aging.

Longevity. Technology: Insilico has been at the forefront of both generative AI and aging research, and has been publishing studies on biomarkers of aging using advanced bioinformatics since 2014. Later, the company trained deep neural networks (DNNs) on human “multi-omics” longitudinal data and retrained them on diseases to develop its end-to-end Pharma. AI platform for target discovery, drug design, and clinical trial prediction.

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