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US and Canada arrest and charge suspected Kimwolf botnet admin

U.S. and Canadian authorities arrested and charged a Canadian man with operating the KimWolf distributed denial-of-service (DDoS) botnet, which infected nearly two million devices worldwide.

23-year-old Jacob Butler (also known online as “Dort”) was arrested by Canadian authorities in Ottawa on Wednesday pursuant to an extradition warrant.

According to a criminal complaint unsealed on Thursday in the District of Alaska, Butler was taken into custody based on IP address and online account information, transaction records, and online messaging records that exposed his links to the KimWolf botnet.

The Scientist Who Plans To End Aging Forever — Aubrey de Grey

Aubrey de Grey believes aging isn’t inevitable — it’s a solvable engineering problem. In this conversation, we explore why society treats aging as untouchable, how “longevity escape velocity” could allow us to live indefinitely, and why reversing damage—not slowing it—is the future of medicine. He breaks down how our medical system profits from sickness, and how progress is slowed by fear and outdated norms. The end of aging as we know it is coming and it’s happening faster than you think. #preventativehealth #preventativecare #aging #health #medicine.

Connect With Me: / tim.doy1e.

Timestamps:
00:00 How We Understand Aging.
06:01 How Aubrey Found His Work.
10:42 Longevity Escape Velocity.
12:45 Not Being Controlled.
15:11 Investor-Humanitarian Structure.
16:51 Balancing Work With Publicity.
17:26 Aubrey’s Current Work.
27:36 Getting Pushback & The Medical System.
33:11 Shifting To Preventative Care.
36:14 What Has & Hasn’t Changed.
41:52 Consciousness & Aging.
46:00 How To Popularize Ideas.
48:10 The Future Of Aubrey’s Work.
50:58 Connect With Aubrey de Grey.

From whole-body to organ-specific biological age clocks

Zalesky and colleagues discuss the evolution of aging clocks into organ-specific aging readouts that harness omics and imaging data. They review the insights that this additional resolution provides on differential aging across organs within interconnected systems, as well as the methods, priorities and future directions.

Aging-associated decline of phosphatidylcholine synthesis is a malleable trigger of natural mitochondrial aging

Mitochondrial decline impairs late-life metabolic plasticity. Using nematodes and human data, this study identifies reduced phosphatidylcholine synthesis as a natural trigger of mitochondrial dysfunction during aging.

Dr. Gregory Fahy on major evidence for human cryopreservation

Dr. Fahy is the Vice President and Chief Scientific Officer at 21st Century Medicine, Inc, and has co-founded Intervene Immune, a company developing clinical methods to reverse immune system aging. He was the 2022–2023 president of the Society for Cryobiology. Dr. Fahy is the lead author of a recent paper, “Ultrastructural and Histological Cryopreservation of Mammalian Brains by Vitrification” – the main topic of our conversation.

In December of 2014, I worked with Dr. Fahy to cryopreserve Dr. Stephen Coles under special conditions, with his permission to extract brain samples and test them for preservation quality. We did not know what the results would be. If bad, that would be discouraging for cryonics. In fact, the results were excellent, as Dr. Fahy details.

We discuss the Coles case and the results of the cerebral cortical biopsy. The paper includes results from rabbit brains. We also discuss the relative resilience of the brain compared to other organs when it comes to fracturing; how cryoprotectants prevent ice formation even when the blood-brain barrier remains closed; whether biostasis organizations should be using blood-brain barrier opening agents; Dr. Fahy’s thoughts about chemical preservation and the role of a combination of cryo an chemo, known as aldehyde-stabilized cryopreservation (ASC), and more.

Character Profile

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