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Dr. Gregory Fahy on major evidence for human cryopreservation
Dr. Fahy is the Vice President and Chief Scientific Officer at 21st Century Medicine, Inc, and has co-founded Intervene Immune, a company developing clinical methods to reverse immune system aging. He was the 2022–2023 president of the Society for Cryobiology. Dr. Fahy is the lead author of a recent paper, “Ultrastructural and Histological Cryopreservation of Mammalian Brains by Vitrification” – the main topic of our conversation.
In December of 2014, I worked with Dr. Fahy to cryopreserve Dr. Stephen Coles under special conditions, with his permission to extract brain samples and test them for preservation quality. We did not know what the results would be. If bad, that would be discouraging for cryonics. In fact, the results were excellent, as Dr. Fahy details.
We discuss the Coles case and the results of the cerebral cortical biopsy. The paper includes results from rabbit brains. We also discuss the relative resilience of the brain compared to other organs when it comes to fracturing; how cryoprotectants prevent ice formation even when the blood-brain barrier remains closed; whether biostasis organizations should be using blood-brain barrier opening agents; Dr. Fahy’s thoughts about chemical preservation and the role of a combination of cryo an chemo, known as aldehyde-stabilized cryopreservation (ASC), and more.
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Could Telomeres Reverse Aging?
What if aging isn’t just “getting older” but the gradual breakdown of the biological systems protecting our DNA? Scientists are now exploring therapies designed to directly lengthen telomeres, the protective caps linked to cellular aging itself. The future of longevity may be far more programmable than we thought.
The Growing Cybersecurity Risks To The Supply Chain In The AI Era
#cybersecurity #suppychains #ai #tech
Supply chains are a primary target for cybercriminals and provide the foundation of global commerce in the hyper-connected digital ecosystem of today. Artificial intelligence (AI) simultaneously exacerbates vulnerabilities as it revolutionizes operations through predictive analytics, automation, and real-time visibility. Sophisticated threat actors, ransomware groups, and nation-state actors employ AI to exploit the vulnerable links in intricate, multi-tiered supply networks.
Artificial intelligence can create dual-use dynamics. It promotes efficiency by facilitating real-time data transfers and hyper-connected operations, while simultaneously significantly expanding the attack surface. Compromises of a single vendor or update have been shown to have a cascading effect on economies, governments, and critical infrastructure through supply chain attacks.
In The AI Era, Supply Chains Are Prime Targets.
The complexity of supply chains is inherent, as they encompass continents, jurisdictions, and a multitude of third-party vendors, contractors, and software components. Each link—whether it be legacy systems, unvetted code, IoT devices, or 5G-enabled connections—provides potential entry points. AI exacerbates these risks by allowing attackers to automate reconnaissance, create polymorphic malware that evades detection, create personalized phishing campaigns, and identify vulnerabilities quicker than defenders can apply patches.
