Many promising therapies fail because of poor patient selection; Harris warns that only about one third of tumors are truly hypoxic, underscoring the need for precise biomarkers in trials.
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Original Doom soundtrack to be inducted into US National Recording Registry
The original Doom soundtrack will be added to the US National Recording Registry.
Composed by Bobby Prince, the 1993 album will be inducted alongside 25 other recordings spanning 70 years. It was selected from more than 3,000 public nominations.
“Key to Doom’s popularity was the adrenaline-fueled soundtrack created by Prince,” the National Recording Registry said.
Wristwatch-like device enables assessment of health risks for astronauts on mission to the moon
Just a few hours before the Orion spacecraft crossed the sky en route to the moon on April 1, mechatronics engineer Rodrigo Trevisan Okamoto received confirmation he had been waiting for since the Artemis 2 mission was announced in 2023. The email from NASA stated that the crew of the first crewed mission to orbit the moon in half a century would carry a device developed by Okamoto and his team at Condor Instruments, a São Paulo-based startup.
“The NASA announcement was sudden and caught us by surprise. And it was only after the mission concluded that we learned the astronauts had been using the equipment in tests for the past two years,” Okamoto told Agência FAPESP.
The device, called an actigraph, is shaped like a wristwatch and incorporates accelerometers, as well as light and temperature sensors, to precisely map the user’s sleep and wake patterns over the course of days or weeks.
Joscha Bach on Synthetic Consciousness & Computational Mind
The provided text outlines Joscha Bach theories regarding the nature of synthetic consciousness and the limitations of modern science. Bach posits that human experience is not a direct interaction with reality, but rather a simulated world model constructed by the brain internal software. He defines intelligence as the capacity to build these models in novel environments, suggesting that current artificial intelligence remains incomplete because it lacks genuine self-understanding. Furthermore, he challenges the narrow focus of contemporary academia and traditional neuroscience, arguing that minds are complex information-processing systems that cannot be explained by neural connections alone. Ultimately, these sources present a computational framework for understanding the self as a functional narrative rather than a mystical or purely physical entity.
Hydrogen puts quantum wormhole conjecture to the test
A new Physical Review Letters study places constraints on the ER = EPR conjecture, showing that under the authors’ assumptions, the conjecture would imply possible alterations to the hyperfine structure and effective charge of the hydrogen atom—effects that have never been observed.
In 1935, Einstein co-authored two distinct papers. The first proposes the Einstein-Podolsky-Rosen (EPR) paradox describing the quantum entanglement of particles. The second one introduces Einstein-Rosen (ER) bridges connecting distant regions of spacetime, which we today call wormholes.
Nearly a century later, in 2013, physicists Juan Maldacena and Leonard Susskind proposed the ER = EPR conjecture, proposing a link between quantum entanglement and wormholes. This links entanglement, a cornerstone of quantum mechanics, with spacetime connectivity, general relativity. This remains one of the major open questions in modern physics.
‘Butterfly’ molecule spotted at last, completing a 20-year quantum zoo hunt
For two decades, physicists have predicted the existence of a remarkable family of exotic molecules: giant atoms bound to ordinary atoms, with an electron so distant from its nucleus that it sculpts the pair into bizarre and diverse shapes. Reported in Physical Review Letters, the final member of this “quantum zoo” has been spotted. Led by Herwig Ott at RPTU University Kaiserslautern-Landau in Germany, a team of physicists has created and detected the “butterfly” molecule, completing a 20-year hunt for the elusive structure.
The molecules in this quantum zoo belong to a class known as ultralong-range Rydberg molecules. They form when an ordinary atom becomes bound to a Rydberg atom, whose outermost electron has been excited so far from the nucleus that the atom swells to thousands of times its normal size.
The orbital shapes traced out by these distant electrons give each molecule type its character, and its nickname. Some have elaborate lobed structures reminiscent of trilobites; others spread into the winged outline of a butterfly. These molecules are thousands of times more sensitive to electric fields than ordinary molecules, making them especially useful objects for probing the quantum world.