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The 700,000-year-old Skull in Greek cave completely shatters the Out of Africa theory

The “Petralona Man,” or “Petralona Archanthropus” is a for 700,000 years old human skull found in 1959. Since then, scientists have tried to locate the origin of this skull, which has created tremendous controversy.

The skull, indicating the oldest human “Europeoid” (presenting European traits), was embedded in a cave’s wall in Petralona, near Chalkidiki in Northern Greece.

A shepherd mistakenly found the cave, dense with stalactites and stalagmites. The cave and skull study was assigned to Dr. Aris Poulianos, an anthropologist specialist, member of UNESCO’s International Union of Anthropology and Ethnology, and president of the Anthropological Association of Greece.

Magnetically Guided Microrobots Deliver Drugs with Pinpoint Accuracy

After numerous successful trials in the model, the team sought to demonstrate what the microrobot could achieve under real clinical conditions. First, they were able to demonstrate in pigs that all three navigation methods worked and that the microrobot remains clearly visible throughout the entire procedure. The investigators then navigated microrobots through the cerebral fluid of a sheep.

“This complex anatomical environment has enormous potential for further therapeutic interventions, which is why we were so excited that the microrobot was able to find its way in this environment too,” Landers noted. “In vivo experiments conducted with an ovine model demonstrated the platform’s ability to operate within anatomically constrained regions of the central nervous system,” the investigators stated in their paper. “Furthermore, in a porcine model, all locomotion strategies were validated under clinical conditions, confirming precise microrobot navigation within the cerebrovascular system and highlighting the system’s compatibility with versatile in vivo environments.”

In addition to treating thrombosis, these new microrobots could also be used for localized infections or tumors. At every stage of development, the research team has remained focused on their goal, which is to ensure that everything they create is ready for use in operating theaters as soon as possible. The next goal is to look at human clinical trials. “The use of materials that have been FDA approved for other intravascular applications, coupled with the modular design of the robotic platform, should simplify translation and adaptability to a range of clinical workflows,” the authors concluded. Speaking about what motivates the whole team, Landers said, “Doctors are already doing an incredible job in hospitals. What drives us is the knowledge that we have a technology that enables us to help patients faster and more effectively and to give them new hope through innovative therapies.”

The Next Superintelligence Will Not Just Think. It Will Bleed

Biology needs the same kind of substrate. Without it, we are still guessing. With it, discovery starts to look predictable by design.

Drug development still leans on animal models and small patient cohorts to make billion-dollar bets. Those proxies teach us something, but they do not teach how a molecule behaves across the complexity of human biology. That is why nine out of ten drugs that succeed in animals fail in human clinical trials.

Biology needs an environment that gives intelligence the same systematic feedback that data centers gave to computation. That is what biological data centers provide. Robotic systems that sustain tens of thousands of standardized human tissues at once. Tissues that are vascularized and immune competent, clinically indistinguishable from patient biopsies under blinded review. Tissues that can be dosed, that bleed, that heal.

Science history: Chemists discover buckyballs — the most perfect molecules in existence — Nov. 14, 1985

Over a feverish 10-day period in 1985, scientists conceived of a new molecule of perfect symmetry — and named it after one of the 20th century’s most famous inventors and futurists.

The hunt started in the 1970s when Harry Kroto, a lab chemist at the University of Sussex in the U.K., was puzzling over the discovery of a primordial soup of organic molecules in the “vast dark clouds that lie between the stars,” Kroto said in his Nobel Prize speech.

New lightweight polymer film can prevent corrosion

MIT researchers have developed a lightweight polymer film that is nearly impenetrable to gas molecules, raising the possibility that it could be used as a protective coating to prevent solar cells and other infrastructure from corrosion, and to slow the aging of packaged food and medicines.

The polymer, which can be applied as a film mere nanometers thick, completely repels nitrogen and other gases, as far as can be detected by laboratory equipment, the researchers found. That degree of impermeability has never been seen before in any polymer, and rivals the impermeability of molecularly-thin crystalline materials such as graphene.

“Our polymer is quite unusual. It’s obviously produced from a solution-phase polymerization reaction, but the product behaves like graphene, which is gas-impermeable because it’s a perfect crystal. However, when you examine this material, one would never confuse it with a perfect crystal,” says Michael Strano, the Carbon P. Dubbs Professor of Chemical Engineering at MIT.

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