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May 26, 2022

Error-free quantum computing gets real

Posted by in categories: computing, information science, particle physics, quantum physics

In modern computers, errors during processing and storage of information have become a rarity due to high-quality fabrication. However, for critical applications, where even single errors can have serious effects, error correction mechanisms based on redundancy of the processed data are still used.

Quantum computers are inherently much more susceptible to disturbances and will thus probably always require error correction mechanisms, because otherwise errors will propagate uncontrolled in the system and information will be lost. Because the fundamental laws of quantum mechanics forbid copying quantum information, redundancy can be achieved by distributing logical quantum information into an entangled state of several physical systems, for example multiple .

The team led by Thomas Monz of the Department of Experimental Physics at the University of Innsbruck and Markus Müller of RWTH Aachen University and Forschungszentrum Jülich in Germany has now succeeded for the first time in realizing a set of computational operations on two logical quantum bits that can be used to implement any possible operation. “For a real-world quantum , we need a universal set of gates with which we can program all algorithms,” explains Lukas Postler, an experimental physicist from Innsbruck.

May 26, 2022

Cryogenic electron microscopy reveals drug targets against common fungus

Posted by in categories: biotech/medical, genetics

Most people carry the fungus Candida albicans on their bodies without it causing many problems. However, a systemic infection with this fungus is dangerous and difficult to treat. Few antimicrobials are effective, and drug resistance is increasing. An international group of scientists, including Albert Guskov, associate professor at the University of Groningen, have used single-particle cryogenic electron microscopy to determine the structure of the fungal ribosome. Their results, which were published in Science Advances on 25 May, reveal a potential target for new drugs.

Candida albicans usually causes no problems, or just an itchy skin infection that is easily treated. However, in rare cases, it may cause systemic infections that can be fatal. Existing antifungal drugs cause a lot of side effects and are expensive. Furthermore, C. albicans is becoming more drug-resistant, so there is a real need for new drug targets. “We noted that no antifungal drugs are targeting protein synthesis, while half of the antibacterial drugs interfere with this system,” says Guskov. A reason for this is that fungal ribosomes, the cellular machineries that translate the genetic code into proteins, are very similar in humans and fungi. “So, you would need a very selective drug to avoid killing our own cells.”

May 26, 2022

CCR5 is a suppressor for cortical plasticity and hippocampal learning and memory

Posted by in categories: biotech/medical, neuroscience

Repression of the G protein-coupled chemokine receptor CCR5 enhances MAPK/CREB signaling, long-term potentiation, somatosensory cortical plasticity, and learning and memory, while CCR5 over-activation by viral proteins may contribute to HIV-associated cognitive deficits.

May 26, 2022

Giant Magnetic Waves Have Been Discovered Oscillating Around Earth’s Core

Posted by in category: evolution

Earth’s interior is a far from quiet place. Deep below our surface activities, the planet rumbles with activity, from plate tectonics to convection currents that circulate through the hot magmatic fluids far underneath the crust.

Now scientists studying satellite data of Earth have identified something inside Earth we’ve never seen before: a new type of magnetic wave that sweeps around the surface of our planet’s core, every seven years.

Continue reading “Giant Magnetic Waves Have Been Discovered Oscillating Around Earth’s Core” »

May 26, 2022

A new approach to therapy-resistant tumors targets a specific cell-death pathway

Posted by in category: biotech/medical

In a paper appearing in Nature today, an international group of scientists report a new way to kill hard-to-treat cancers. These tumors resist current immunotherapies, including those using Nobel Prize-winning checkpoint-blocking antibodies.

The approach exploits Z-DNA. Rather than twisting to the right like B-DNA, Z-DNA has a left-handed twist. One role for Z-DNA is to regulate the to viruses. The response involves AADR1 and ZBP1, two proteins that specifically recognize Z-DNA. They do so through a Zα domain that binds to the Z-DNA structure with high affinity.

The Zα domain was originally discovered by Dr. Alan Herbert of InsideOutBio, a communicating author on the paper. The ADAR1 Zα domain turns off the , while the other ZBP1 Zα turns on pathways that kill virally infected , as previously shown by Dr. Sid Balachandran, the other communicating author on the paper. The interactions between ADAR1 and ZBP1 determine whether a cell lives or dies.

May 25, 2022

How the universe got its magnetic field

Posted by in categories: cosmology, engineering

When we look out into space, all of the astrophysical objects that we see are embedded in magnetic fields. This is true not only in the neighborhood of stars and planets, but also in the deep space between galaxies and galactic clusters. These fields are weak—typically much weaker than those of a refrigerator magnet—but they are dynamically significant in the sense that they have profound effects on the dynamics of the universe. Despite decades of intense interest and research, the origin of these cosmic magnetic fields remains one of the most profound mysteries in cosmology.

In previous research, scientists came to understand how turbulence, the churning motion common to fluids of all types, could amplify preexisting magnetic fields through the so-called dynamo process. But this remarkable discovery just pushed the mystery one step deeper. If a turbulent dynamo could only amplify an existing field, where did the “seed” magnetic field come from in the first place?

We wouldn’t have a complete and self-consistent answer to the origin of astrophysical magnetic fields until we understood how the seed fields arose. New work carried out by MIT graduate student Muni Zhou, her advisor Nuno Loureiro, a professor of nuclear science and engineering at MIT, and colleagues at Princeton University and the University of Colorado at Boulder provides an answer that shows the basic processes that generate a field from a completely unmagnetized state to the point where it is strong enough for the dynamo mechanism to take over and amplify the field to the magnitudes that we observe.

May 25, 2022

Mechanism Responsible for Information Transfer Between Different Regions of the Brain Discovered

Posted by in category: neuroscience

Summary: Increasing synchronization of neurons in the upstream brain region that transmits information leads to a significant improvement in the transmission of information and information processing in the downstream region.

Source: Bar-Ilan University.

In the early 20th century scientists began to record brain activity using electrodes attached to the scalp. To their surprise, they saw that brain activity is characterized by slow and rapid ascending and descending signals which were subsequently called “brain waves”.

May 25, 2022

Dutch researchers teleport quantum information across rudimentary quantum network

Posted by in categories: computing, internet, quantum physics

Scientists realize quantum teleportation between remote, non-neighboring nodes in a quantum network. The network employs three optically connected nodes based on solid-state spin qubits. The teleporter is prepared by establishing remote entanglement on the two links, followed by entanglement swapping on the middle node and storage in a memory qubit.

They demonstrate that once successful preparation of the teleporter is heralded, arbitrary qubit states can be teleported with fidelity above the classical bound, even with unit efficiency. These results are enabled by key innovations in the qubit readout procedure, active memory qubit protection during entanglement generation and tailored heralding that reduces remote entanglement infidelities.

Continue reading “Dutch researchers teleport quantum information across rudimentary quantum network” »

May 25, 2022

Researchers may have found the missing link between Alzheimer’s and vascular disease

Posted by in categories: biotech/medical, neuroscience

𝙏𝙝𝙚 𝙘𝙤𝙣𝙙𝙞𝙩𝙞𝙤𝙣𝙨 𝙘𝙖𝙣 𝙖𝙡𝙡 𝙖𝙛𝙛𝙚𝙘𝙩 𝙩𝙝𝙚 𝙗𝙧𝙖𝙞𝙣, 𝙙𝙖𝙢𝙖𝙜𝙞𝙣𝙜 𝙗𝙡𝙤𝙤𝙙 𝙫𝙚𝙨𝙨𝙚𝙡𝙨 𝙖𝙣𝙙 𝙡𝙚𝙖𝙙𝙞𝙣𝙜 𝙩𝙤 𝙨𝙩𝙧𝙤𝙠𝙚𝙨. 𝘽𝙪𝙩 𝙩𝙝𝙚 𝙘𝙤𝙣𝙣𝙚𝙘𝙩𝙞𝙤𝙣 𝙗𝙚𝙩𝙬𝙚𝙚𝙣 𝙫𝙖𝙨𝙘𝙪𝙡𝙖𝙧 𝙙𝙞𝙨𝙚𝙖𝙨𝙚 𝙞𝙣 𝙩𝙝𝙚 𝙗𝙧𝙖𝙞𝙣 𝙖𝙣𝙙 𝘼𝙡𝙯𝙝𝙚𝙞𝙢𝙚𝙧’𝙨 𝙝𝙖𝙨 𝙧𝙚𝙢𝙖𝙞𝙣𝙚𝙙 𝙪𝙣𝙚𝙭𝙥𝙡𝙖𝙞𝙣𝙚𝙙 𝙙𝙚𝙨𝙥𝙞𝙩𝙚 𝙩𝙝𝙚 𝙞𝙣𝙩𝙚𝙣𝙨𝙚 𝙚𝙛𝙛𝙤𝙧𝙩𝙨 𝙤𝙛 … See more.

The Neuro-Network.

𝐑𝐞𝐬𝐞𝐚𝐫𝐜𝐡𝐞𝐫𝐬 𝐦𝐚𝐲 𝐡𝐚𝐯𝐞 𝐟𝐨𝐮𝐧𝐝 𝐭𝐡𝐞 𝐦𝐢𝐬𝐬𝐢𝐧𝐠 𝐥𝐢𝐧𝐤 𝐛𝐞𝐭𝐰𝐞𝐞𝐧 𝐀𝐥𝐳𝐡𝐞𝐢𝐦𝐞𝐫’𝐬 𝐚𝐧𝐝 𝐯𝐚𝐬𝐜𝐮𝐥𝐚𝐫 𝐝𝐢𝐬𝐞𝐚𝐬𝐞

Continue reading “Researchers may have found the missing link between Alzheimer’s and vascular disease” »

May 25, 2022

Digital Technology Demands A New Political Philosophy

Posted by in categories: futurism, robotics/AI

Men like Zuckerberg and Musk are the subject of fascination. Their character, their genius, their flaws — all are treated to feverish scrutiny. Since Musk’s bid for Twitter, there has been a predictable flurry of speculation: does he know what he’s doing? Is he a troll or a revolutionary? Will he improve conditions of free speech? What, if anything, will he do about online harassment and extremism?

Though valuable and interesting, it is possible that these kinds of questions obscure the deeper issue, or at least the longer-term one. At root, the big question for the future of powerful technologies is this: whether they are ultimately economic entities which should be governed according to market principles, or whether they are in fact political in nature, and so should be governed by democratic norms and principles. In the long run, the answer we provide to this question will significantly affect the course of democracy around the world — more, in any event, than whether Musk himself understands the concept of “free speech absolutism.”

Many other advanced democracies are tacking toward the political/democratic option. The UK is considering a landmark Online Safety Bill, which will place strict duties on social media platforms. Off the back of the General Data Protection Regulation, the EU is readying a swathe of new measures — an Artificial Intelligence Act, a Digital Services Act, a Digital Markets Act — all of which will curb the power of tech firms.