Lifeboat Foundation

And how we can use them. “The Landscape of AI Tools” is published by HungryMinded in Seeds For The Future.

When the makers of electronic implants abandon their projects, people who rely on the devices have everything to lose.

Clean energy will reduce dependency on Russia and Arab countries for oil and gas.

What if the weight could instead be distributed between multiple support poles? That’s the design Eolink has in mind; its floating turbine swaps out the single large pole for four thinner ones angled towards each other in a pyramid shape. This not only distributes the weight of the turbine’s pieces, it allows the whole structure to be lighter.

The turbine Eolink plans to build as a proof of concept will have a generating capacity of five megawatts and weigh 1,100 tons. Its base will be a square with each side 171 feet (52 meters) long, and its rotor’s diameter will be 469 feet (143 meters). For reference, that’s about one and a half Big Bens, or four-fifths of the Washington Monument.

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FTX founder Sam Bankman-Fried was arrested in the Bahamas at the behest of US prosecutors on Monday, the day before he was due to testify before Congress about the abrupt failure last month of one of the world’s largest cryptocurrency exchanges.

#FTX #SamBankmanFried #Bahamas.

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Solar cell technology is a seen as a key pillar in our transition to cleaner forms of energy, but within this field there is all kinds of room for experimentation. Solar cells that are thin and flexible hold unique promise in the area, as they could be applied to all kinds of irregular, curvy or otherwise unsuitable surfaces. Thinner than a human hair, a new lightweight solar cell from MIT scientists continues to push the envelope in this space.

The MIT team behind the technology sought to build on its previous advances in material science, which in 2016 culminated in ultra-thin solar cells light enough to sit atop a soap bubble without breaking it. As is the case with other thin, light and flexible solar cells we’ve looked at over the years, this pointed to all kinds of possibilities, from paper-based electronics to lightweight wearables that harvest energy throughout your day.

Despite the potential, the team still had some problems to solve, with the fabrication technique for the solar cells requiring vacuum chambers and expensive vapor deposition methods. In order to scale the technology up, the scientists have now turned to ink-based printable materials to streamline the process.

“The ARRW team successfully designed and tested an air-launched hypersonic missile in five years,” Brig. Gen. Jason Bartolomei, program executive officer for the Air Force’s armament directorate. “I am immensely proud of the tenacity and dedication this team has shown to provide a vital capability to our warfighter.”

Hypersonic weapons can travel at speeds greater than Mach 5 and maneuver mid-flight, making them much harder to track and shoot down than conventional ballistic missiles and capable of penetrating defenses. Russia and China have invested heavily in developing their own hypersonic weapons, and the U.S. military has faced pressure, including from lawmakers, to show more progress on its own hypersonic capabilities.

The successful test of the operational ARRW prototype continues a series of successful tests for the program in 2022, marking a turnaround from a disappointing 2021 that left the effort in trouble.

Huntington’s disease (HD) is a neurological disorder that causes progressive loss of movement, coordination and cognitive function. It is caused by a mutation in a single gene called huntingtin (HTT). More than 200,000 people worldwide live with the genetic condition, approximately 30,000 in the United States. More than a quarter of a million Americans are at risk of inheriting HD from an affected parent. There is no cure.

But in a new study, published December 12, 2022 in Nature Neuroscience, researchers at University of California San Diego School of Medicine, with colleagues elsewhere, describe using RNA-targeting CRISPR/Cas13D technology to develop a new therapeutic strategy that specifically eliminates toxic RNA that causes HD.

CRISPR is known as a genome-editing tool that allows scientists to add, remove or alter genetic material at specific locations in the genome. It is based on a naturally occurring immune defense system used by bacteria. However, current strategies run the risk of off-target edits at unintended sites that may cause permanent and inheritable chromosomal insertions or genome alterations. Because of this, significant efforts have focused on identifying CRISPR systems that target RNA directly without altering the genome.

An international research team led by Dr. Ana Guadaño at the Alberto Sols Biomedical Research Institute (IIBM, a combined CSIC-UAM center) and involving the Complutense University of Madrid (UCM), used CRISPR gene editing techniques to incorporate into mice a mutation of the MCT8 protein responsible for transporting thyroid hormones to the interior of the cell.

Patients with mutations in this protein suffer from Allan-Herndon-Dudley syndrome, a rare disease that takes the form of serious neurological alterations, in which each patient may reveal a different mutation of MCT8.

This study, published in Neurobiology of Disease, describes the first avatar model for the disease—in other words, the first animal model with the same genetic alteration as various patients.

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