Lifeboat Foundation

An enzyme that defends human cells against viruses can help drive cancer evolution towards greater malignancy by causing myriad mutations in cancer cells, according to a study led by investigators at Weill Cornell Medicine. The finding suggests that the enzyme may be a potential target for future cancer treatments.

In the new study, published recently in the journal Cancer Research, scientists used a preclinical model of bladder cancer to investigate the role of the enzyme called APOBEC3G in promoting the disease and found that it significantly increased the number of mutations in tumor cells, boosting the genetic diversity of bladder tumors and hastening mortality.

“Our findings suggest that APOBEC3G is a big contributor to bladder cancer evolution and should be considered as a target for future treatment strategies,” said study senior author Dr. Bishoy M. Faltas, assistant professor of medicine in the Division of Hematology and Medical Oncology and of cell and developmental biology at Weill Cornell Medicine, and an oncologist who specializes in urothelial cancers at NewYork-Presbyterian/Weill Cornell Medical Center.

According to recent research individuals who use statins, a class of drugs that decrease cholesterol levels may have a decreased risk of an intracerebral hemorrhage. Intracerebral hemorrhage is a type of stroke caused by bleeding in the brain. The study was recently published in the journal Neurology.

“While statins have been shown to reduce the risk of stroke from blood clots, there has been conflicting research on whether statin use increases or decreases the risk of a person having a first intracerebral hemorrhage,” said study author David Gaist, MD, Ph.D., of the University of Southern Denmark in Odense and a member of the American Academy of Neurology. “For our study, we looked at the lobe and non-lobe areas of the brain to see if the location was a factor for statin use and the risk of a first intracerebral hemorrhage. We found that those who used a statin had a lower risk of this type of bleeding stroke in both areas of the brain. The risk was even lower with long-term statin use.”

The lobe area of the brain includes most of the cerebrum, including the frontal, parietal, temporal, and occipital lobes. The non-lobe area primarily includes the basal ganglia, thalamus, cerebellum, and brainstem.

When Japan’s Hayabusa mission traveled to asteroid Itokawa, it collected samples. These successfully reached Earth in 2010.

Near Earth asteroid Itokawa is a rubble pile that formed more than four billion years ago, a new study found. So, these asteroids might be resilient to demise.

A gene called BPIFB4, discovered in a population of centenarians, could help to reverse the aging of human hearts.

Carriers of healthy mutant genes, including people in so-called “blue zones” of the world, often live to 100 years or more and remain in good health. Cardiovascular complications are also rarer in these individuals. Scientists now believe that a gene may help to keep their hearts young by protecting them against diseases linked to aging.

Summary: Synaptic pruning occurs as a result of mechanical tearing, a new study reveals.

Source: University of Munster.

Nerve cells communicate with one another via long processes known as axons and dendrites, or, more generally, neurites. During development, these processes first grow and form connections with other cells, for example synapses with other nerve cells. Any neurites which are not properly linked, or are no longer needed, are removed by a corrective mechanism known as “pruning”.

‘This technology may be scaled to monitor the well-being of elderly people or just identify suspicious behaviours at home,’ scientists claim Scientists have figured out how to identify people in a building by using artificial intelligence to analyse WiFi signals. A team at Carnegie Mellon University developed a deep neural network to digitally map human bodies when in the presence of WiFi signals.

Researchers have claimed that artificial intelligence (AI) will reach the singularity within seven years, after attempting to quantify its progress.

Translation company Translated, presenting their work at an Association for Machine Translation in the Americas conference, explained that they first began testing machine translation technology in 2011. The team settled on a metric to measure AI progress, which they’ve called “Time to Edit” (TTE). Simply put, it is the time it takes a human translator to edit a translation produced by another human or an AI.

Over the years, the TTE for AI-translated texts has come down fairly consistently, leading Translated to predict the date when AI hits the singularity, when the time is equivalent to human translators.

Researchers may have made a massive breakthrough in quantum computing. According to a new study published in Nature Nanotechnology, researchers may have discovered a cheaper way to push large-scale quantum computers.

Quantum computing is an intriguing field that has seen quite a bit of growth over the past several years. However, there’s still a lot holding back the massive computers that researchers are working with – namely, their size and the sheer amount of control required to keep large-scale quantum computers running smoothly.

That’s because the larger you make a quantum computer, the more quantum bits, or qubits, it requires to run. And the entire idea of a quantum computer requires you to control every single one of those qubits to keep things running smoothly and efficiently. So, when you make large-scale quantum computers, you end up with a lot of processing power and a lot more qubits to control.

A chatbot powered by reams of data from the internet has passed exams at a US law school after writing essays on topics ranging from constitutional law to taxation and torts.

ChatGPT from OpenAI, a US company that this week got a massive injection of cash from Microsoft, uses artificial intelligence (AI) to generate streams of text from simple prompts.

The results have been so good that educators have warned it could lead to widespread cheating and even signal the end of traditional classroom teaching methods.