Lifeboat Foundation

In 2021, one of the record years in biotechnology investments, about 50 drugs were approved by the FDA. 36 of these were small molecules. In my opinion, only about 5 of these were truly innovative targeting novel mechanisms and novel targets. The 10th revision of the International Classification of Diseases (ICD) contained 55,000 codes for diseases, injuries and conditions. Even if we assume that there are only 10,000 diseases, 50 FDA approvals per year seems to be an extraordinarily small number.

The reason for this small number of innovative and effective therapeutics is the long time, high cost, and low probability of success of drug discovery and development. On average, this process takes 12 years, costs over $2 Billion dollars and fails over 90% of the time. The most innovative therapeutics with novel targets have even higher probability of failure. To get these 50 drugs approved in 2021, the pharmaceutical companies globally spent over $100 Billion and over a decade.

The biotechnology industry is very different from any other industry and it is important to understand how it works, and the role China plays in delivering safe and effective medicines to suffering patients worldwide. Sharing risk, expenses, and infrastructure will result in acceleration of global biotechnology and increase the number of innovative drug approvals. Closer collaboration between the US and China in biotechnology would allow investors to share huge risks and returns while benefiting everyone on the planet and making this world a much better place.

“She cooks, she cleans, and she still finds time to play ball with Elroy,” George and Jane Jetsons’ six-and-a-half-year-old son. Set in the year 2062 and described in the 1960s animated sitcom The Jetsons as an “aluminum-encased, battery-powered robotic maid” who is the “perfect answer for any modern family,” Rosie the Robot takes care of chores around the house while also serving as friend and confidante of mother Jane. Sarcastic and funny, Rosie is a hardworking nanny and aunt figure to children Elroy and Judy.

While many technologies The Jetsons predicted for 2062 have become reality, such as video calls and smart watches, the full realization of robots as the 1960s ideal friend and helper who makes life easier has yet to be fulfilled. For twenty-five years, roboticist Daniel Theobald has been on a mission to create robots that can solve the world’s most pressing problems. But rather than focus solely on making robots be more human, his calling has been to use them to help humans be more human.

Continue reading “Meet The Roboticist Working To Make Robots Help Us Be More Human” »

Despite surges in fields like AI, medicine and nuclear energy, major advances in science and technology are slowing and are fewer and farther between than decades ago, according to a study published in Nature.

The researchers analyzed some 45 million scientific papers and 3.9 million patents between 1945 and 2010, examining networks of citations to assess whether breakthroughs reinforced the status quo or disrupted existing knowledge and more dramatically pushed science and technology off into new directions.

Across all major scientific and technological fields, these big disruptions—the discovery of the double helix structure of DNA, which rendered earlier research obsolete, is a good example of such research—have become less common since 1945, the researchers found.

We can expect to the latest and greatest in gaming and computer hardware, audio visual, electric vehicles and smart home technologies.

Both the European Space Agency and NASA are planning to test even more sensitive sensors on future moon missions to try and hone in on satellite signals. If they can truly connect with sats back home, we could get closer to achieving autonomous moon travel. But eventually that won’t be enough. To help direct humans on the lunar surface, we’re going to need a fleet of satellites specifically around the moon. NASA calls its project LunaNet, and it’s part of the Gateway space station, which is the culmination of America’s plan to return to the moon. It needs to be designed to play well with ESA technology and, eventually, will be the source of high-speed internet on the moon.

Artemis I launched back in November, rounded the moon just 81 miles above the lunar surface and touched down Earth-side in December. Artemis II, which will carry astronauts around the moon in a similar trajectory, is slated to launch in late 2024, according to Space.com. Artemis III, which will be humanity’s first boots on the moon since 1972, could launch as early as 2025.

Ray Kurzweil, an American Jewish inventor and futurist, claims that within ten years, man will be able to defeat old age and death thanks to the accelerated development of technology.

My question in relation to Kurzweil’s statement is: What is so good about us constantly living all the time? Why live at all if we are never to die?

Continue reading “Ray Kurzweil Thoughts on Immortality — A Kabbalist’s Response” »

In this episode, David and Peter discuss aging as a disease, the technology needed to reverse aging, and tips and tricks to increase your lifespan.

David Sinclair is a biologist and academic known for his expertise in aging and epigenetics. Sinclair is a genetics professor and the Co-Director of Harvard Medical School’s Paul F. Glenn Center for Biology of Aging Research. He’s been included in Time100 as one of the 100 Most Influential People in the World, and his research has been featured all over the media. Besides writing a New York Times Best Seller, David has co-founded several biotech companies, a science publication called Aging, and is an inventor of 35 patents.
Read David’s book, Lifespan: Why We Age-and Why We Don’t Have To: https://a.co/d/85H3Mll.

Continue reading “Why Aging is a Disease With David Sinclair | EP #18 Moonshots and Mindsets” »

Is a monthly journal publishing new concepts in biological technology of relevance to bioengineering, medicine, energy, agriculture, food…

An engine idea that can accelerate to 99 percent of the speed of light, all without the need for propellant. That may sound like something out of a science fiction movie, but it’s not. This is exactly what one of NASA engineers is developing, and it promises to break the law of physics.

How will these engines be developed? If it is going to work without propellant, then what will be its fuel? And most importantly, will a human be able to travel in a vehicle with such an engine as its thruster? Well, we will find out in just a second.