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Nerve cells require vast amounts of energy and oxygen which they receive through the bloodstream. This results in nerve tissue being densely intertwined with numerous blood vessels. However, what prevents neurons and vascular cells from interfering with each other during growth? Researchers from the Universities of Heidelberg and Bonn, in collaboration with international partners, have uncovered a mechanism that ensures this coordination. The findings have recently been published in the journal Neuron.

Nerve cells are highly energy-intensive, requiring a large amount of fuel. Approximately 20% of the calories we consume through food are dedicated to our brain, as the generation of voltage pulses (action potentials) and transmission between neurons is incredibly energy-demanding. For this reason, nerve tissue is usually crisscrossed by numerous blood vessels. They ensure a supply of nutrients and oxygen.

During embryonic development, a large number of vessels sprout in the brain and spinal cord, but also in the retina of the eye. Additionally, masses of neurons are formed there, which network with each other and with structures such as muscles and organs. Both processes have to be considerate of each other so as not to get in each other’s way. “We have identified a new mechanism that ensures this,” explains Prof. Dr. Carmen Ruiz de Almodóvar, member of the Cluster of Excellence ImmunoSensation2 and the Transdisciplinary Research Area Life & Health at the University of Bonn.

What will the future of AI programming look like with tools like ChatGPT and GitHub Copilot? Let’s take a look at how machine learning could change the daily lives of developers in the near future.

#ai #tech #TheCodeReport.

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Ask any question in text and it’ll return the answer in under 30 seconds. This will make data analysis 10x faster

Research in mice suggests that a gene associated with longevity in humans could help rejuvenate the aging heart and improve cardiovascular health.

Human astrocytes are larger and more complex than those of infraprimate mammals, suggesting that their role in neural processing has expanded with evolution. To assess the cell-autonomous and species-selective properties of human glia, we engrafted human glial progenitor cells (GPCs) into neonatal immunodeficient mice. Upon maturation, the recipient brains exhibited large numbers and high proportions of both human glial progenitors and astrocytes. The engrafted human glia were gap-junction-coupled to host astroglia, yet retained the size and pleomorphism of hominid astroglia, and propagated Ca²⁺ signals 3-fold faster than their hosts. Long-term potentiation (LTP) was sharply enhanced in the human glial chimeric mice, as was their learning, as assessed by Barnes maze navigation, object-location memory, and both contextual and tone fear conditioning. Mice allografted with murine GPCs showed no enhancement of either LTP or learning. These findings indicate that human glia differentially enhance both activity-dependent plasticity and learning in mice.

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The internet is abuzz with mentions of Comet C/2022 E3 (ZTF) a.k.a., the green comet, which on Wednesday could be seen with the naked eye.

As per NASA, the comet paid our planet a visit after a good 50,000 years. It was a rare feast for stargazers and astronomers alike as people around the globe witnessed the astronomical event.

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Have you ever used Alexa to help you decide what movie you should watch? Maybe you asked Siri for restaurant recommendations. Artificial intelligence and virtual assistants are constantly being refined, and may soon be making appointments for you, offering medical advice, or trying to sell you a bottle of wine.

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Neuroscientists have successfully increased the motivation to exert mental effort by using a weak alternating electrical current sent through electrodes attached to the scalp to synchronize brain waves. The findings, published in Cognitive, Affective, & Behavioral Neuroscience, help to identify the neural mechanisms underlying the willingness to engage in mental effort, suggesting that midfrontal theta oscillations play a key role.

“For a long time research has mainly focussed on which brain mechanisms underlie mental processes, but in the recent years it has become clear that engaging in mental activities needs to be understood as an active decision process where humans are willing to perform demanding mental tasks only if they are ‘worth it.’ The goal of our research was to get a better understanding of the brain mechanisms causally determining our motivation to engage in demanding mental activities,” explained study author Alexander Soutschek, a research group leader at the psychology department of the University of Munich.

For their study, the researchers utilized transcranial alternating current stimulation (tACS), a non-invasive neurostimulation technique that applies low-amplitude electrical current to the scalp through electrodes. The current modulates the neural activity in the brain regions under the electrodes, potentially enhancing or suppressing specific cognitive processes.