Lifeboat Foundation

Summary: Researchers developed one of the most comprehensive 3D models of the synapse, the neuron juncture crucial for intercellular communication. This breakthrough allows an unprecedented view of the complex interactions between individual cells at the synapse, offering fresh insights into neurodegenerative diseases such as Huntington’s disease and schizophrenia.

The team used this novel approach to compare healthy mice brains to those with the Huntington’s mutant gene, revealing structural flaws potentially disrupting cellular communication. The researchers believe this technique could significantly advance our understanding of various neurodegenerative and neuropsychiatric diseases.

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Continue reading “Vitamin B6 Didn’t Impact NAD (Test Results)” »

A novel type of neural network is helping physicists with the daunting challenge of data analysis.

The aim of non-pharmacologic interventions for brain health is to preserve cognitive function and safeguard brain structure. This review explores various diets (MeDi, DASH, MIND, ketogenic), exercise approaches (endurance, resistance, yoga, HIIT), and highlights the need for further research to uncover the underlying mechanisms.

Seeing a supernova, or an exploding star, is a unique spectacle in itself. But recently, astronomers have found something even more unique: A star explosion so “extremely warped” that it looked like it was multiple images in the sky.

So how did this happen?

It’s not magic, according to the California Institute of Technology, but an effect known as “gravitational lensing,” which happens when gravity from a dense object in space “distorts and brightens the light of an object behind it.” In the case of supernova SN Zwicky, it was the gravity of another galaxy that impacted its appearance.

As people get older, they tend to have lower levels of anxiety. But why? A new brain imaging study has found that older individuals are faster at recognizing and responding to negative emotions. The findings, published NeuroImage, go against the idea that older adults are less engaged with negative emotions due to cognitive decline or that they are better at regulating negative emotions. Instead, the results suggest that older adults may develop a more automatic way of processing negative emotions.

The study aimed to investigate the relationship between aging, trait anxiety, and changes in cognitive and affective functions. The researchers were motivated by previous findings that older adults tend to have lower susceptibility to anxiety disorders compared to younger and middle-aged adults. However, it was not clear how age-related changes in anxiety symptoms, such as worry and somatic symptoms, were related to changes in cognitive and affective processes.

“We are interested in emotion dysfunction in early dementia, including those people with subjective complaints of memory problem and mild cognitive impairment,” said study author Chiang-shan Ray Li, a professor of psychiatry and neuroscience at Yale University School of Medicine.

In my new Newsweek Op-Ed, I tackle a primary issue many people have with trying to stop aging and death via science. Hopefully this philosophical argument will allow more resources & support into the life extension field:

Philosophers often say if humans didn’t die, we’d be bored out of our minds. This idea, called temporal scarcity, argues the finitude of death is what makes life worth living. Transhumanists, whose most urgent goal is to use science to overcome biological death, emphatically disagree.

For decades, the question of temporal scarcity has been debated and analyzed in essays and books. But an original idea transhumanists are putting forth is reinvigorating the debate. It doesn’t discount temporal scarcity in biological humans; it discounts it in what humans will likely become in the future—cyborgs and digitized consciousnesses.

Continue reading “Eliminating Death Doesn’t Mean Life Will Get Boring” »

Researchers at IBM pitted their 127-qubit Eagle quantum computer against a conventional supercomputer in a challenge to perform a complex calculation – and the quantum computer won.

By Karmela Padavic-Callaghan

The research is a result of observations from awake language mapping during brain tumor surgery.

A team of Chinese researchers has developed a way to artificially produce speech, also known as speech synthesis, using cues from neural brain activity.

According to the South China Morning Post, the researchers claim that they have a mind-reading machine that is capable of turning human thought into spoken Mandarin.