Lifeboat Foundation

Artificial intelligence can predict on-and off-target activity of CRISPR tools that target RNA instead of DNA, according to new research published in Nature Biotechnology.

The study by researchers at New York University, Columbia University, and the New York Genome Center, combines a deep learning model with CRISPR screens to control the expression of human genes in different ways—such as flicking a light switch to shut them off completely or by using a dimmer knob to partially turn down their activity. These precise gene controls could be used to develop new CRISPR-based therapies.

CRISPR is a gene editing technology with many uses in biomedicine and beyond, from treating sickle cell anemia to engineering tastier mustard greens. It often works by targeting DNA using an enzyme called Cas9. In recent years, scientists discovered another type of CRISPR that instead targets RNA using an enzyme called Cas13.

OpenAI’s large language models (LLMs) are trained on a vast array of datasets, pulling information from the internet’s dustiest and cobweb-covered corners.

But what if such a model were to crawl through the dark web — the internet’s seedy underbelly where you can host a site without your identity being public or even available to law enforcement — instead? A team of South Korean researchers did just that, creating an AI model dubbed DarkBERT to index some of the sketchiest domains on the internet.

It’s a fascinating glimpse into some of the murkiest corners of the World Wide Web, which have become synonymous with illegal and malicious activities from the sharing of leaked data to the sale of hard drugs.

SAN MATEO, Calif. — A flying car being developed for both roadways and vertical takeoff and landing capabilities is now one step closer to becoming a reality after receiving a special approval from the U.S. Federal Aviation Administration.

Alef Aeronautics, based in San Mateo, California, has been developing the Model A flying car, which is 100% electric and will carry one or two occupants.

The company envisions the car, which costs roughly $300,000, saving individuals time during the commutes with the ability to fly over stopped traffic and accidents on roadways.

Don’t know where the nearest café is? Or if it will rain today? Or even the meaning of life? Fear not, ask your e-bike.

An avant-garde company in the cycling industry has found the solution to your long lonely rides.

Continue reading “‘Bicycle with a mind’: Urtopia announces World’s first e-bike with ChatGPT” »

The US space agency continues to look toward the private sector as it plans for life beyond the International Space Station.

NASA has awarded a Space Act Agreement contract to Special Aerospace Services (SAS) to develop a commercial version of its Autonomous Maneuvering Unit (AMU) astronaut jetpack.

The move comes as the US space agency looks ahead to a future without the International Space Station (ISS), in which private companies will build and lift a series of commercial space stations to low Earth orbit.

What lies underneath Mars’ surface? Space scientists have long been curious about whether Mars’ core is solid or liquid.

What lies underneath Mars’ surface? Space scientists have long been curious whether Mars’ core is solid or liquid.

A team of experts led by the Royal Observatory of Belgium has discovered that Mars most likely has a liquid core.

The ground-based space station comprises multiple chambers that simulate different environments, ranging from the lunar surface to microgravity.

China has developed first-of-its-kind space station simulators to conduct various experiments and test instruments on Earth, as per the South China Morning Post (SCMP)

Reportedly, the researchers have already begun the first experimental operations of this project, known as the ground space station.

An early experiment in older rhesus macaques suggests that an injection of klotho improves working memory. Could it one day help people?

PORTSMOUTH, Va. (WAVY) – Artificial intelligence is already revolutionizing society – from healthcare and education to cybersecurity and even our courts. Despite all of its benefits, it has also given criminals an edge when it comes to deceiving us.

Financial sextortion is a crime in which a bad actor attempts to leverage personal material (think: naked pictures or videos) to force a victim into giving into their demands — usually money or other compromising material.