Lifeboat Foundation

This study demonstrates that AI can be incredibly effective in helping us identify new drug candidates – particularly at early stages of drug discovery and for diseases with complex biology or few known molecular targets.

A machine learning model has been trained to recognise the key features of chemicals with senolytic activity. It recently found three chemicals able to remove senescent cells without damaging healthy cells.

Molecular structure of oleandrin. Credit: Mplanine, CC BY-SA 4.0, via Wikimedia Commons.

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The company wants to make large-scale quantum computers a reality within just 10 years.

Artificial intelligence has made remarkable progress in recent years, but can it help us talk to animals? Explore the possibilities and limitations of AI in communicating with other species.

Researchers at Microsoft say they have created elusive quasiparticles called Majorana zero modes – but scientists outside the company are sceptical.

By Karmela Padavic-Callaghan

That’s the ordinary matter of everyday life: your hair and clothes, your atoms and organs, the food you eat and the dogs that kiss you, the air and the sea, the Sun and the Moon. Everything we know — everything we see — is just 5% of everything in the Universe.

The remaining 95% of the Universe is stuff that we can’t see, don’t yet understand. An extraordinarily vast portion of the cosmos is still unknown. Despite the technological advancements of the last century, even with computers at our fingertips and the worldwide internet and space-based observatories mapping the far reaches of our Universe, there is still so much that we don’t understand.

We have grown leaps and bounds since the days of the ancient Greeks and Egyptians, even since Copernicus and Kepler. But in many ways, we are still novices playing with toy models seeking to understand the stars.

For many years, the fields of physics and chemistry have held the belief that the properties of solid materials are fundamentally determined by the atoms and molecules they consist of. For instance, the crystalline nature of salt is credited to the ionic bond formed between sodium and chloride ions. Similarly, metals such as iron or copper owe their robustness to the metallic bonds between their respective atoms, and the elasticity of rubbers stems from the flexible bonds in the polymers that form them. This principle also applies to substances like fungi, bacteria, and wood.

Or so the story goes.

A new paper recently published in Nature upends that paradigm, and argues that the character of many biological materials is actually created by the water that permeates these materials. Water gives rise to a solid and goes on to define the properties of that solid, all the while maintaining its liquid characteristics.

People who owned black-and-white television sets until the 1980s didn’t know what they were missing until they got a color TV. A similar switch could happen in the world of genomics as researchers at the Berlin Institute of Medical Systems Biology of the Max Delbrück Center (MDC-BIMSB) have developed a technique called Genome Architecture Mapping (“GAM”) to peer into the genome and see it in glorious technicolor. GAM reveals information about the genome’s spatial architecture that is invisible to scientists using solely Hi-C, a workhorse tool developed in 2009 to study DNA interactions, reports a new study in Nature Methods by the Pombo lab.

With a black-and-white TV, you can see the shapes but everything looks grey. But if you have a color TV and look at flowers, you realize that they are red, yellow and white and we were unaware of it. Similarly, there’s also information in the way the genome is folded in three-dimensions that we have not been aware of.

Lot’s of science news, stay till the end for the climate stuff.

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Scientists have solved a decades-long mystery on whether light can be effectively trapped in a 3D forest of microscopic particles.

Using a new method for crunching vast sums in a model of particle interactions, a team of physicists in the US and France revealed conditions under which a wave of light can be brought to a standstill by defects in the right kind of material.

Known as Anderson localization, after US theoretical physicist Philip W. Anderson, electrons can become trapped (localized) in disordered materials with randomly distributed abnormalities. Its proposal in 1958 was a significant moment in contemporary condensed matter physics, applying across quantum as well as classical mechanics.