Lifeboat Foundation

Year 2019 mini fusion device 😗😁.

Researchers spot the signatures of nuclear fusion in a table-top-sized setup commonly used to study the plasmas found in stars and other astrophysical objects.

Year 2022 😗😁

Better chemistry through computing: #ILLINOIS researchers led an international team that combined powerful AI and a molecule-making machine to automate complex chemistry.

“We really didn’t know which way it would go,” he said.

To find out, the researchers generated versions of the enzymes that would specifically move into the nucleus and bypass the mitochondria. They discovered that this relocation fortified the cells, keeping them alive. They demonstrated that this process worked in both heart cells generated from human stem cells and in mice exposed to chemotherapy.

“This seems to be a new mechanism by which heart cells can defend themselves against chemotherapy damage,” noted Rehman, who is also a member of the University of Illinois Cancer Center.

The earlier that Alzheimer’s disease and other similar conditions can be spotted, the better the treatment options are, and scientists have discovered a blood biomarker that could signal the risk of dementia many years in advance.

A team from the National Institute on Aging, the University of Texas, and the Johns Hopkins Bloomberg School of Public Health in the US, as well as other institutions across the world, looked at data on 10,981 individuals collected across the course of 25 years.

In particular, the researchers analyzed the proteome of these individuals: the complete set of proteins expressed in a body, driving all kinds of biological processes from cell communication to hormone levels.

The use of “smart drugs” to enhance productivity in academic and workplace settings is on the rise. A recent study published in Science Advances examined the effects of three popular smart drugs – methylphenidate, modafinil, and dextroamphetamine – on real-life tasks. The researchers hypothesized that these drugs, which affect dopamine and norepinephrine, would influence motivation and effort, ultimately leading to improved performance.

The study involved forty participants between the ages of 18 and 35. The participants were randomly assigned to four groups and attended four testing sessions. In each session, they were given one of three popular smart drugs or a placebo. The drugs were administered in a double-blinded manner, meaning neither the participants nor the researchers knew which drug was being given.

The researchers used a task called the “knapsack task” to evaluate the participants’ cognitive performance. This task involves solving a complex optimization problem where participants have to select items with certain weights and values to maximize the overall value while staying within a weight limit. The difficulty of the task was designed to simulate real-life complex tasks that people encounter.

A potent anti-cancer therapy has been created using Nobel prize-winning “click chemistry,” where molecules click together like LEGO bricks, in a new study by UCL and Stanford University researchers.

The study, published in Nature Chemistry, opens up new possibilities for how cutting-edge cancer immunotherapies might be built in future.

The research team created an anti-cancer therapy with three components: one targeting the cancer cell, another recruiting a white blood cell called a T cell to attack the cancer cell, and a third knocking out part of the cancer cell’s defenses.

Looking only at their subatomic particles, most materials can be placed into one of two categories.

Metals—like copper and iron—have free-flowing electrons that allow them to conduct electricity, while insulators —like glass and rubbe r— keep their electrons tightly bound and therefore do not conduct electricity.

Insulators can turn into metals when hit with an intense electric field, offering tantalizing possibilities for microelectronics and supercomputing, but the physics behind this phenomenon called resistive switching is not well understood.

The world’s best artificial intelligence (AI) systems can pass tough exams, write convincingly human essays and chat so fluently that many find their output indistinguishable from people’s. What can’t they do? Solve simple visual logic puzzles.

In a test consisting of a series of brightly coloured blocks arranged on a screen, most people can spot the connecting patterns. But GPT-4, the most advanced version of the AI system behind the chatbot ChatGPT and the search engine Bing, gets barely one-third of the puzzles right in one category of patterns and as little as 3% correct in another, according to a report by researchers this May¹.

The team behind the logic puzzles aims to provide a better benchmark for testing the capabilities of AI systems — and to help address a conundrum about large language models (LLMs) such as GPT-4. Tested in one way, they breeze through what once were considered landmark feats of machine intelligence. Tested another way, they seem less impressive, exhibiting glaring blind spots and an inability to reason about abstract concepts.

The weaponization of the scientific and technological breakthroughs stemming from human genome research presents a serious global security challenge. Gene-editing pioneer and Nobel Laureate Jennifer Doudna often tells a story of a nightmare she once had. A colleague asked her to teach someone how her technology works. She went to meet the student and “was shocked to see Adolf Hitler, in the flesh.”

Doudna is not alone in being haunted by the power of science. Famously, having just returned home from Los Alamos in early 1945, John von Neumann awakened in panic. “What we are creating now is a monster whose influence is going to change history, provided there is any history left,” he stammered while straining to speak to his wife. He surmised, however, that “it would be impossible not to see it through, not only for military reasons, but it would also be unethical from the point of view of the scientists not to do what they knew is feasible, no matter what terrible consequences it may have.”

According to biographer Ananyo Bhattacharya, von Neumann saw what was happening in Nazi Germany and the USSR and believed that “the best he could do is allow politicians to make those [ethical and security] decisions: to put his brain in their hands.” Living through a devastating world war, the Manhattan Project polymath “had no trust left in human nature.”