Lifeboat Foundation: Safeguarding Humanity
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August 3, 2015 The question of why we age is one of the most fascinating questions for humankind, but nothing close to a satisfactory answer has been found to date. Scientists at the Leibniz-Institut für Molekulare Pharmakologie in Berlin have now shown, for the first time, that the ER loses its oxidative power in advanced age, which shifts the reducing/oxidising equilibrium — redox for short — in this compartment. This leads to a decline in the capacity to form the disulphide bridges that are so important for correct protein folding. As a consequence, many proteins can no longer mature properly and become unstable.

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Serendipity has as much a place in science as in love. That’s what Northeastern physicists Swastik Kar and Srinivas Sridhar found during their four-year project to modify graphene, a stronger-than-steel infinitesimally thin lattice of tightly packed carbon atoms. Primarily funded by the Army Research Laboratory and Defense Advanced Research Projects Agency, or DARPA, the researchers were charged with imbuing the decade-old material with thermal sensitivity for use in infrared imaging devices such as night-vision goggles for the military.

What they unearthed, published Friday in the journal Science Advances, was so much more: an entirely new material spun out of boron, nitrogen, carbon, and oxygen that shows evidence of magnetic, optical, and electrical properties as well as DARPA’s sought-after thermal ones. Its potential applications run the gamut: from 20-megapixel arrays for cellphone cameras to photo detectors to atomically thin transistors that when multiplied by the billions could fuel computers.

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Synthetic biology programming microorganisms to perform some new functions. Genes are made out of DNA; synthetic biology involves inserting synthetic genes that might not have existed before into yeast and reprogramming them to make a new chemistry or things not made naturally by biology. Each gene codes for an enzyme. One can program a new set of enzymes and convert them to intermediate products. If you go through five or even 15 steps, you can get a final product – a polymer, a new drug – creating a chemical factory inside a cell. This is much better than nanotechnology, because in synthetic biology, we get down to molecular size…

Prof. Joseph Jacobson, a leading physicist at the Massachusetts Institute of Technology, is not only the inventor of e-ink but also a mover in creating artificial DNA to eventually cure diseases.

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Professor Hyun-Gyu Park of the Department of Chemical and Biomolecular Engineering at Korea Advanced Institute of Science and Technology (KAIST) has developed a technique to analyze various target DNAs using an aptamer, a DNA fragment that can recognize and bind to a specific protein or enzyme. This technique will allow the development of affordable genetic diagnosis for new bacteria or virus, such as Middle Ease Respiratory Syndrome (MERS). The research findings were published in the June issue of Chemical Communications, issued by the Royal Society of Chemistry in the United Kingdom. The paper was selected as a lead article of the journal.

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