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Genetically engineered muscles power tiny, light-sensitive biobots. Continue reading →

An international team of scientists has set a new record for the complexity possible on a quantum computing chip, bringing us one step closer to the ultra-secure telecommunications of the future.

Image: Shutterstock.

CHAMPAIGN, Ill. — A new class of miniature biological robots, or bio-bots, has seen the light — and is following where the light shines.

The bio-bots are powered by muscle cells that have been genetically engineered to respond to light, giving researchers control over the bots’ motion, a key step toward their use in applications for health, sensing and the environment. Led by Rashid Bashir, the University of Illinois head of bioengineering, the researchers published their results in the Proceedings of the National Academy of Sciences.

“Light is a noninvasive way to control these machines,” Bashir said. “It gives us flexibility in the design and the motion. The bottom line of what we are trying to accomplish is the forward design of biological systems, and we think the light control is an important step toward that.”

A research team led by the University of Leeds has observed for the first time how HIV and Ebola viruses attach to cells to spread infection.

The findings, published today in the journal Angewandte Chemie (“Compact, Polyvalent Mannose Quantum Dots as Sensitive, Ratiometric FRET Probes for Multivalent Protein-Ligand Interactions”), offer a new way of treating such viruses: instead of destroying the pathogens, introduce a block on how they interact with cells.

Continue reading “‘Sweet’ quantum dots light the way for new HIV and Ebola treatment” »

For Gartner and their Emerging Tech graph; may wish to rethink the biosensor being over 10 years away.

MicroRNAs are a newly discovered class of short (about 19 to 24 nuclides in length) fragments of noncoding RNAs that are useful biomarkers for diagnosing various diseases, including cardiac disease and some cancers. Since they are surprisingly well preserved in fluids such as urine and blood, their detection is well suited to a rapid, point-of-care method.

Mi Kyoung Park at the A*STAR Institute of Microelectronics and her co-workers have devised a silicon photonic biosensor that can detect tiny changes in the phase of a light beam caused by hybridization between an immobilized DNA probe and target microRNAs in a sample.

Continue reading “On-the-spot diagnosis of certain cancers with sensitive bionsensor” »

Behold – the only known example of a biological wheel. Loved by creationists, who falsely think they are examples of “intelligent design”, the bacterial flagellum is a long tail that is spun like a propeller by nano-sized protein motors.

Now these wheels and their gearing have been imaged in high resolution and three dimensions for the first time. Morgan Beeby and his colleagues at Imperial College London used an electron microscope to resolve the mechanisms that provide different amounts of torque to the motors.

The motors are diverse, coming in a wide variety of shapes, sizes and power outputs. Indeed, the diversity of the motors and the fact that they have evolved many times in different bacterial lineages, scuppers the creationist view that the machinery is “irreducibly complex”.

Continue reading “High-power biological wheels and motors imaged for first time” »

Polymers laden with chemotherapy drugs assemble at tumor cells and slip past their defenses.

A team of researchers at The Hong Kong Polytechnic University (PolyU) has designed a biosensor that uses an optical method called upconversion luminescence resonance energy transfer (LRET) for virus detection within 2–3 hours. Its cost is around HK$20 ($2.50) per sample—about 80% lower than traditional testing methods—and can be used for detecting different types of viruses, shedding new light on the development of low-cost, rapid, and ultrasensitive detection of different viruses.

Related: Infectious disease control with portable CMOS-based diagnostics

Traditional biological methods for flu virus detection include genetic analysis—reverse transcription-polymerase chain reaction (RT-PCR) and enzyme-linked immunosorbent assay (ELISA) used in immunology. However, RT-PCR is expensive and time-consuming, while the sensitivity for ELISA is relatively low. Such limitations make them difficult for clinical use as a front-line and onsite diagnostic tool for virus detection.

Continue reading “Newly developed optical biosensor can detect viruses quickly and cheaply” »

Good news for MRIs; maybe witht he precision we also may not have to do any repeat scans as well.

Precision Glass & Optics recently announced the customization of two thin film optical components for a high-field magnetic resonance imaging (MRI) accessory. They developed the dielectric cold mirror and cylindrical prism mirror for the Real Eye Nano; an advanced visual presentation and eye-tracking system constructed of glass and plastic with a reduced size for operation in confined MRI spaces.