Jul 11, 2016
BRCA mutations linked to prostate and uterine cancers
Posted by Karen Hurst in categories: biotech/medical, genetics
Personally; I have heard this several years ago from some medical researchers. Glad that more have concluded this tie.
Genetic mutations on several genes including BRCA2 have been associated with prostate cancer; while in a separate study, a BRCA1 mutation has been linked to a particular form of uterine cancer.
The first study, published in the New England Journal of Medicine, found that 12 percent of men with advanced prostate cancer had inherited mutations in genes involved in the repair of damaged DNA.
Professor Johann de Bono of the Institute of Cancer Research in London and the Royal Marsden NHS Foundation Trust, who led the study, said: ‘Our study has shown that a significant proportion of men with advanced prostate cancer are born with DNA repair mutations – and this could have important implications for patients.