Lifeboat Foundation

2 November 2016. Two companies partnering with Auburn University developed a synthetic virus to find and destroy tumor cells in a type of bone cancer in dogs. Financial and intellectual property aspects of the agreement between synthetic gene company Gen9 in Cambridge, Massachusetts, design systems developer Autodesk Inc. in San Rafael, California, and Auburn University College of Veterinary Medicine in Alabama were not disclosed.

The research team created a synthetic version of canine adenovirus type 2, or CAV2, a virus usually associated with hepatitis in dogs. In this case, the synthetic CAV-2 virus is designed as an oncolytic virus that finds and attacks cancer cells, while leaving healthy cells and tissue intact. The genome in the organism is believed to be the longest in a functional virus synthesized for cancer research, with about 34,000 base pairs of nucleic acids. The human genome, by comparison, has about 3 billion base pairs.

The technology provided by Gen9 in this project makes it possible to eventually produce synthetic therapeutic viruses tailored for specific patients. Gen9 offers customized gene synthesis and is developing a library of synthesized proteins and antibodies. One of the 4 year-old company’s founders is George Church, a geneticist at Harvard Medical School and serial entrepreneur. In August 2016, as reported in Science & Enterprise, Church and colleagues, including those from Gen9, developed a synthetic E. coli bacteria genome with redundant DNA components removed.

When the future of genetic engineering arrived on Sebastian Cocioba’s doorstep, it was affixed to the back of a postcard from Austria with a little bit of packing tape.

Cocioba is a 25-year-old college dropout whose primary interest is tinkering with plant genetics in a lab he cobbled together from eBay. The lab is located in the spare bedroom of his parent’s lavish apartment in Long Island City, across the river from Manhattan. A few months ago, an internet friend from an online bio-hacking forum had sent him the lab’s latest addition: attached to that postcard was Crispr-Cas9.

Inverse doing a recap from my AMA on Reddit’s Futurology. My AMA is going on for about another 15 hours, so if you have a question, please chime in there: https://www.inverse.com/article/23120-zoltan-istvan-formula-1-sports-future and here’s the AMA:

https://www.reddit.com/r/Futurology/comments/5aq3mw/ama_im_z…manist_us/ #transhumanism #AMA #ScienceCandidate #Election2016

The U.S. presidential candidate has shared some of his future goals ahead of voting day.

Continue reading “Transhumanist Zoltan Istvan: Formula 1 is Future of Human Sports” »

We now know the mass of an axion, which means we might be able to prove dark matter does indeed exist.

Scientists have been working for decades on engineered viruses that can hunt down and get inside cancer cells, cause them to burst and spur the immune system to mop up whatever malignant cells might be left behind. Only one such treatment has successfully become an FDA-approved cancer treatment.

That one drug, from Amgen, isn’t selling much. But that small victory a year ago has emboldened others to go forward with their own ideas to advance this approach to cancer therapy, known as oncolytic virus therapy.

One of the aspiring players in the oncolytic virus field, Ottawa, Canada-based Turnstone Biologics, is announcing today it has raised $41.4 million in a Series B venture financing. The round was led by OrbiMed Advisors, and included F-Prime Capital Partners and a couple of existing investors, FACIT and Versant Ventures. The new money will add on to the $11.3 million Series A round from a year ago.

Continue reading “Engineering Viruses to Kill Cancer Cells, Canada-Based Turnstone Raises $41.4M” »

From time to time, the Singularity Hub editorial team unearths a gem from the archives and wants to share it all over again. It’s usually a piece that was popular back then and we think is still relevant now. This is one of those articles. It was originally published October 25th, 2015. We hope you enjoy it!

It’s the most exciting time to be alive, and thanks to tech, it’s only getting better.

Researchers plan to bring dead to life by freezing their brains and then resurrecting them with artificial intelligence.

Bringing the dead back to life is futuristic and final frontier of science and Humai is working on just that. Humai is a technology company based in Los Angeles and is working on a project known as “Atom & Eve” that would let human consciousness be transferred to an artificial body after their death.

The artificial intelligence company has said it can resurrect human beings within the next 30 years. The “conversational styles, [behavioural]patterns, thought processes and information about how your body functions from the inside-out” would be stored on a silicon chip through AI and nanotechnology.

Continue reading “A technology that can bring dead back to life might be a reality soon” »

Have you ever been in a situation where knowing another language would have come in handy?

I remember standing on the platform at Tokyo Station watching my train to Nagano — the last train of the day — pulling away without me on it. What ensued was a frustrating hour of gestures, confused smiles, and head-shaking as I wandered the station looking for someone who spoke English (my Japanese is unfortunately nonexistent). It would have been really helpful to have a bilingual pal along with me to translate.

Bilingual pals can be hard to find, but Google’s new translation software may be an equally useful alternative. In a paper released last week, the authors noted that Google’s Neural Machine Translation system (GNMT) reduced translation errors by an average of 60% compared to Google’s phrase-based system. GMNT uses deep learning, a technology that aims to ‘think’ in the same way as a human brain.

Continue reading “A Computer Can Now Translate Languages as Well as a Human” »