Lifeboat Foundation

When Jan Scheuermann volunteered for an experimental brain implant, she had no idea she was making neuroscience history.

Scheuermann, 54 at the time of surgery, had been paralyzed for 14 years due to a neurological disease that severed the neural connections between her brain and muscles. She could still feel her body, but couldn’t move her limbs.

Unwilling to give up, Scheuermann had two button-sized electrical implants inserted into her motor cortex. The implants tethered her brain to a robotic arm through two bunches of cables that protruded out from her skull.

Continue reading “New Tech Makes Brain Implants Safer and Super Precise” »

Nice.

Current can literally blow copper interconnects away, but graphene could keep them intact.

Photoemission spectroscopy has detected two different populations of spin-polarized electrons that are “hidden” within a layered, graphene-like material.

The layers inside certain materials can carry spin-polarized electrons, but this polarization is hidden to measurements that aren’t sufficiently localized. A new study using photoemission spectroscopy has detected the hidden spin polarization in a graphene-like material called molybdenum disulfide (MoS22). Unique to this work is the ability to target specific populations of spin-polarized electrons with circularly polarized light.

A three-photon microscopic video of neurons in a mouse brain. The imaging depth is approximately 1 millimeter below the surface of the brain. The firing of the neurons is captured by an indicator that is based on green fluorescent protein GFP, which glows brighter as the neuron sends a signal.

Nearly four years ago, then-President Obama launched the BRAIN (Brain Research through Advancing Innovative Neurotechnologies) Initiative, to “accelerate the development and application of new technologies that will enable researchers to produce dynamic pictures of the brain.”

Several of the program’s initial funding awards went to Cornell’s Chris Xu, the Mong Family Foundation Director of Cornell Neurotech – Engineering, and professor and director of undergraduate studies in applied and engineering physics. Xu’s projects aimed to develop new imaging techniques to achieve large scale, noninvasive imaging of neuronal activity.

Continue reading “Group develops deep, non-invasive imaging of mouse brain” »

“As academics we can sign petitions, but it is not enough.”

As academics we can sign petitions, but it is not enough. Scott Aaronson wrote very eloquently about this issue after the initial ban was announced (see also Terry Tao). My department has seen a dramatic decrease in the number of applicants in general and not just from Iran. We were just informed that we can no longer make Teaching Assistant offers for students who are unlikely to get a visa to come here.

The Department of Homeland Security has demonstrated its blatant disregard for moral norms. Why should we trust its scientific norms? What confidence do we have that funding will not be used in some coercive way? What does it say to our students when we ask them to work for DHS? Yes, the government is big, but at some point the argument that it’s mostly the guy at the top who is bad but the rest of the agency is still committed to good science becomes just too hard to swallow. I decided that I can’t square that circle. Each one of us should think hard about whether we want to.

Continue reading “Why I Will No Longer Do Research Sponsored By The Department Of Homeland Security” »

DNA, the stuff of life, may very well also pack quite the jolt for engineers trying to advance the development of tiny, low-cost electronic devices.

Much like flipping your light switch at home — –only on a scale 1,000 times smaller than a human hair — –an ASU-led team has now developed the first controllable DNA switch to regulate the flow of electricity within a single, atomic-sized molecule. The new study, led by ASU Biodesign Institute researcher Nongjian Tao, was published in the advanced online journal Nature Communications ( DOI: 10.1038/ncomms14471).

“It has been established that charge transport is possible in DNA, but for a useful device, one wants to be able to turn the charge transport on and off. We achieved this goal by chemically modifying DNA,” said Tao, who directs the Biodesign Center for Bioelectronics and Biosensors and is a professor in the Fulton Schools of Engineering.

Continue reading “Switched-on DNA spark nano-electronic applications” »

Contrary to what has long been believed, the role of the sympathetic nervous system in muscle tissue goes far beyond controlling blood flow by contracting or relaxing blood vessels, according to studies conducted at the University of São Paulo (USP) in Brazil.

With support from FAPESP and the collaboration of researchers at Mannheim University and Heidelberg University in Germany, a group of Brazilian researchers led by Isis do Carmo Kettelhut and Luiz Carlos Carvalho Navegantes at the University of São Paulo’s Ribeirão Preto Medical School (FMRP –USP) have demonstrated the importance of sympathetic innervation for the growth and maintenance of muscle mass and also for the control of movement.

Kettelhut is a full professor at FMRP -USP’s Biochemistry & Immunology Department. Navegantes is a professor in the same institution’s Physiology Department.

Continue reading “Study Reveals Essential Role of Sympathetic Nerves in Muscle Health” »

Green: NAc-projecting prefrontal cortex neurons become active during the presentation of a reward-predictive cue, and this activity drives reward-seeking behavior. Purple: PVT-projecting prefrontal cortex neurons inhibited during reward-predictive cue. Credit: The Stuber Lab (UNC School of Medicine)

The prefrontal cortex, a large and recently evolved structure that wraps the front of the brain, has powerful “executive” control over behavior, particularly in humans. The details of how it exerts that control have been elusive, but UNC School of Medicine scientists, publishing today in Nature, have now uncovered some of those details, using sophisticated techniques for recording and controlling the activity of neurons in live mice.

Got OCD; check your genes for a mutation.

A new Northwestern Medicine study found evidence suggesting how neural dysfunction in a certain region of the brain can lead to obsessive and repetitive behaviors much like obsessive-compulsive disorder (OCD).

Both in humans and in mice, there is a circuit in the brain called the corticostriatal connection that regulates habitual and repetitive actions. The study found certain synaptic receptors are important for the development of this brain circuit. If these receptors are eliminated in mice, they exhibit obsessive behavior, such as over-grooming.

Continue reading “OCD-like behavior linked to genetic mutation, study finds” »