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For the more than 1 million Americans who live with type 1 diabetes, daily insulin injections are literally a matter of life and death. And while there is no cure, a Cornell University-led research team has developed a device that could revolutionize management of the disease.

In Type 1 diabetes, insulin-producing pancreatic cell clusters (islets) are destroyed by the body’s immune system. The research group, led by assistant professor Minglin Ma from the Department of Biological and Environmental Engineering, has devised an ingenious method for implanting hundreds of thousands of islet cells into a patient. They are protected by a thin hydrogel coating and, more importantly, the coated cells are attached to a polymer thread and can be removed or replaced easily when they have outlived their usefulness.

Transplantation of stem cell-derived, insulin-producing is an alternative to insulin therapy, but that requires long-term immunosuppressive drug administration. One well-researched approach to avoid the immune system’s response is to coat and protect the cells in tiny hydrogel capsules, hundreds of microns in diameter. However, these capsules cannot be taken out of the body easily, since they’re not connected to each other, and there are hundreds of thousands of them.

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Engineers at The Ohio State University are developing technologies that have the potential to economically convert fossil fuels and biomass into useful products including electricity without emitting carbon dioxide to the atmosphere.

In the first of two papers published in the journal Energy & Environmental Science, the engineers report that they’ve devised a process that transforms shale gas into products such as methanol and gasoline—all while consuming carbon dioxide. This process can also be applied to coal and biomass to produce useful products.

Under certain conditions, the technology consumes all the carbon dioxide it produces plus additional carbon dioxide from an outside source.

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Engineers at The Ohio State University are developing technologies that have the potential to economically convert fossil fuels and biomass into useful products including electricity without emitting carbon dioxide to the atmosphere.

In the first of two papers published in the journal Energy & Environmental Science, the engineers report that they’ve devised a process that transforms shale gas into products such as methanol and gasoline—all while consuming carbon dioxide. This process can also be applied to coal and biomass to produce useful products.

Under certain conditions, the consumes all the carbon dioxide it produces plus additional carbon dioxide from an outside source.

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Oh, Cheez…We’re back to this question, again!

As a Bitcoin columnist, I get this question a lot. Today, an answer was requested at Quora.com, where I am the lead contributor on cryptocurrencies:

“Clearly, some people value Bitcoin. But How can
this be? There is nothing there to give it value!”

Many individuals, like the one who asked this question, suspect that Bitcoin was pulled out of thin air—and that it is not backed by gold, a government, or an authoritative redemption guaranty. After all, it is just open source code. What stops me from creating an ElleryCoin using the same code?!

Let’s start with the short answer:

  • Indeed, it was pulled out thin air
  • It isn’t backed by an asset, government or promise
  • You could easily clone Bitcoin (the entire mining ecosystem) and distribute it yourself. It would be exactly like Bitcoin. Yet, Bitcoin is clearly valued by everyone, and your new coin is unlikely to generate interest or adoption.

A More Complete Answer: What is value?

Bitcoin has more intrinsic value than a government printed paper bill. The value arises from a combiation of fundamental properties:

  • It has a capped supply
  • It is widely recognized, liquid, and resistant to legislation
  • It has attained the robust supply-demand of a growing, 2-sided network.
  • It is open and transparent. This elevates user trust
  • Unlike cash and credit, Bitcoin requires no back-end settlement. That’s because it is not a payment instrument. Rather it is money itself.
  • Finally, it’s value is likely to be durable, because it is not printed by a country that has racked up debt. In fact, it can never be inflated.

Downside and Risks

But wait! What about the long transaction delay and high cost? There are sharp disagreements anong miners, users and developers concerning block size, transaction malleability, and replay issues. Aren’t these a deal killers? And what about wild volatility in the exchange rate? Doesn’t this retard adoption as a functional currency?

These are transient issues associated with a new technology. Although Bitcoin is weathering growth pains that arise from a new and distributed governance technology (democracy can be messy!), all of these issues have sound solutions. We have already witnessed and tested the solyutions with various forked coins. Think of them as beta tests. Even if current problems delay the day when you can spend bitcoin at every retail establishment—it is already sucking liquidity from national currencies and becoming the world’s de facto reserve currency.

Many individuals find all of this hard to accept. That is because we have been conditioned to think that ‘value’ arises from assets with ‘intrinsic’ value, the promise of redemption, or by edict. This is not true. In all things, (including gold, a Picasso painting, or your labor) value arises from simple supply and demand.

Some individuals claim that all other factors are secondary. But, even this statement is false. All other factors are irrelevant. They may be related, but they are not the source of value.

I recognize that this answer may seem smug or definitive. So, allow me to suggest related questions with answers that are a bit more interesting, because they are subtle. Unlike the question of value, these two questions are open to analysis and opinion: (1) “Will people continue to value bitcoin in the future?” — And (2) “When will Bitcoin stop swinging wildly in value?” (measured by its exchange rate with other currencies).

This is fun! Let’s explore…


Philip Raymond co-chairs CRYPSA, publishes A Wild Duck and hosts the New York Bitcoin Event. Last month, he kicked off the Cryptocurrency Expo in Dubai. Click Here to inquire about a live presentation or consulting engagement.

A review of the discoveries in lifespan extension reported in 2017.


Summary: a review of the discoveries in lifespan extension reported in 2017. [Author: Brady Hartman. This article first appeared on the LongevityFacts.com website. The article has been updated, and the title has been changed.]

Another year is over. Here’s a look back at the discoveries and articles covering lifespan extension science in 2017.

Videos on Lifespan Extension

Summary: Biomarkers of aging would be a breakthrough that slashes the time and cost it currently takes to develop lifespan-extension drugs. [Author: Brady Hartman. This article first appeared on the LongevityFacts.com website. ]

Biomarkers of aging would revolutionize the development of lifespan-extension drugs, helping to bring them out of the laboratory and into the clinic in a fraction of the time and at a fraction of the cost. The first scientist to come up with an effective biomarker of aging would produce a true breakthrough for the field of life extension.

Imagine that geroscientists have just developed a miraculous compound called Regulus that promises to extend human lifespans by a significant amount. Unfortunately, the researchers would not have an easy time testing Regulus because humans live a long time. Testing Regulus in mice, would help, but researchers would still have to test the drug’s lifespan-extending effects in humans. Before anti-aging physicians could prescribe Regulus, it would need to undergo an expensive and lengthy clinical trial.

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Summary: These breakthroughs in stem cell therapy could potentially rejuvenate our damaged organs with induced pluripotent stem cells (iPSCs). Moreover, biotech firms are rushing to bring organ-rejuvenating cell therapies to the marketplace. [This article first appeared on the LongevityFacts.com website. Author: Brady Hartman. ]

Recent advances in stem cell therapies could translate into effective treatments for intractable diseases.

Stem cells are the repairmen of our bodies. Unlike our ordinary cells, stem cells can divide without limit and create fresh copies of nearly any tissue type to repair damaged organs. While we have an abundance of these repairmen in our youth, we experience stem cell decline as we age.

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Researchers find promising Alzheimer’s treatment with a diabetes drug that ‘significantly reversed memory loss.’


Promising alzheimer’s treatment using diabetes drug.

Scientists announced a drug that ‘significantly reversed memory loss’ in mice with Alzheimer’s disease.

Researchers from Lancaster University in the UK say the novel drug – created to treat type 2 diabetes – works through a triple method of action and also add that the medicine could provide substantial improvements in the treatment of Alzheimer’s disease. The drug combines three growth factors that act in multiple ways to protect the brain from degeneration. The Lancaster University scientists published their study results on January 1 in the journal Brain Research.

Summary: New findings on maximum human lifespan shows that we have an upper limit due to the construction of our bodies and genetic constraints. However, anti-aging scientists may have discovered ways to overcome this limitation. [This article first appeared on the LongevityFacts website. Author: Brady Hartman. ]

Three new studies show that maximum human lifespan is limited to about 115 – 120 years due to genetic constraints, the construction of our bodies and an increasingly toxic environment.

These studies are hardly the first to conclude there is a maximum human lifespan. However, there may be a way to overcome this limitation.

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