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Jun 15, 2017

LEAF President Keith Comito explains the origin of Lifespan.io and why crowdfunding research to extend healthy lifespan is both important and exciting

Posted by in categories: biotech/medical, life extension

You may not be familiar with the work we do at Lifespan.io and how we are supporting rejuvenation biotech research using the power of crowdfunding. Here is a short video talking about the importance of supporting breakthrough technology and the work we do at Lifespan.io.


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Jun 14, 2017

Father of deep learning AI on General purpose AI and AI to conquer space in the 2050s

Posted by in categories: robotics/AI, space

Juergen Schmidhuber is the father of Deep learning Artificial Intelligence.

Since age 15 or so, the main goal of professor Jürgen Schmidhuber has been to build a self-improving Artificial Intelligence (AI) smarter than himself, then retire. His lab’s Deep Learning Neural Networks (NNs) (since 1991) and Long Short-Term Memory have transformed machine learning and AI, Deep Learning since 1991 – Winning Contests in Pattern Recognition and Sequence Learning Through Fast and Deep / Recurrent Neural Networks and are now (2017) available to billions of users through the world’s most valuable public companies including Google, Apple, Microsoft, Amazon, etc. In 2011, his team was the first to win official computer vision contests through deep NNs, with superhuman performance. His research group also established the field of mathematically rigorous universal AI and recursive self-improvement in universal problem solvers that learn to learn (since 1987).

Continue reading “Father of deep learning AI on General purpose AI and AI to conquer space in the 2050s” »

Jun 14, 2017

Bionic knee brace

Posted by in categories: cyborgs, transhumanism

This bionic knee brace will give you superhuman strength…and it’s available to everyone!

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Jun 14, 2017

50 shades of Gal Gadot: The genetic truth behind Wonder Woman’s race

Posted by in categories: genetics, internet

An argument is raging on internet whether Wonder Woman is white or a person of color. Here are the facts.

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Jun 14, 2017

Making Humans a Multi-Planetary Species

Posted by in categories: Elon Musk, space travel

Elon Musk’s paper on, available for free below.


This paper is a summary of Elon Musk’s presentation at the 67th International Astronautical Congress in Guadalajara, Mexico, September 26–30, 2016. In February 2017, SpaceX announced it will launch a crewed mission beyond the moon for two private customers in late 2018.

Used with permission from SpaceX.

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Jun 14, 2017

Scientists Reverse DNA Damage in Mice. Human Trials are Next

Posted by in categories: biotech/medical, life extension

Sinclair lab enters human trials for DNA repair this year!


DNA is a critical part of the cell, it is the instruction manual for building cells. Whilst DNA is well protected within the cell nucleus damage does occur, therefore DNA repair is absolutely essential for cell function, cell survival and the prevention of cancer. The good news is cells are able to repair damaged DNA but the bad news is that this ability declines with aging for reasons as yet to be fully understood.

An exciting new study by researchers led by Dr. David Sinclair at Harvard Medical School shows a part of the process that enables cells to repair damaged DNA involving the signalling molecule NAD. This offers insight into how the body repairs DNA and why that repair system declines as we age. Before we get into the new research study let’s take a look at how DNA damage relates to aging and what NAD is.

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Jun 14, 2017

Full Rotation Of The Moon!

Posted by in category: space

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Jun 14, 2017

NASA-Funded Startup to Build Fusion-Powered Rockets

Posted by in categories: nuclear energy, physics, satellites

Nuclear fusion is the process that powers the sun, but closer to home scientists are trying to develop fusion reactors that could provide immense amounts of energy. These reactors are big and (currently) inefficient, but a NASA-funded startup called Princeton Satellite Systems is working on a small-scale fusion reactor that could power advanced fusion rockets. Suddenly, other planets and even other star systems could be in reach.

All the forms of rocket propulsion we currently have involve accelerating propellant out of a nozzle. Then, physics takes over and the vessel moves in the opposite direction. Most spacecraft use chemical propulsion, which provides a large amount of thrust over a relatively short period of time. Some missions have been equipped with ion drives, which use electrical currents to accelerate propellant. These engines are very efficient, but they have low thrust and require a lot of power. A fusion rocket might offer the best mix of capabilities.

Current nuclear reactors use fission to generate energy; large atomic nuclei are broken apart and some of that mass is transformed into energy. Fusion is the opposite. Small atomic nuclei are fused together, causing some mass to be converted into energy. This is what powers stars, but we’ve had trouble producing the necessary temperatures and pressure on Earth to get net positive energy generation.

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Jun 14, 2017

Organ chips get smart and go electric

Posted by in categories: biotech/medical, computing, engineering, health, neuroscience

Organs-on-Chips (Organ Chips) are emerging as powerful tools that allow researchers to study the physiology of human organs and tissues in ways not possible before. By mimicking normal blood flow, the mechanical microenvironment, and how different tissues physically interface with one another in living organs, they offer a more systematic approach to testing drugs than other in vitro methods that ultimately could help to replace animal testing.

As it can take weeks to grow human cells into intact differentiated and functional tissues within Organ Chips, such as those that mimic the lung and intestine, and researchers seek to understand how drugs, toxins or other perturbations alter tissue structure and function, the team at the Wyss Institute for Biologically Inspired Engineering led by Donald Ingber has been searching for ways to non-invasively monitor the health and maturity of cells cultured within these microfluidic devices over extended times.

It has been particularly difficult to measure changes in electrical functions of cells grown within Organ Chips that are normally electrically active, such as neuronal cells in the brain or beating heart cells, both during their differentiation and in response to drugs.

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Jun 14, 2017

Reaching a Consensus on Aging Biomarkers

Posted by in categories: biotech/medical, life extension

Whilst looking through recent papers about biomarkers and this recent open access paper crossed my desk. The paper is the latest in a line of top to bottom reviews of aging biomarkers for humans. With companies like Unity Biotechnology and the David Sinclair lab entering human clinical trials later this year for senescent cell removal and DNA repair respectively, the development of effective biomarkers to measure how someone is aging and how therapies effect that are a matter of urgency.

Given that there are various causes of aging and that rejuvenation therapies will generally only target one or two of these processes, the first therapies will likely only be partially effective. The aging processes are all interlinked as well so affecting one may effect others, hence there is a need for a comprehensive panel of biomarkers in order for researchers to prove the efficacy of therapies.

Another thing to consider with a therapy such as senescent cell removal is, whilst you can measure how effective it is at removing senescent cells (to a reasonable degree using β-galactosidase etc…) being able to demonstrate the wider benefits of doing so is trickier. So the challenge here is to find a suitable range of biomarkers that can provide a good level of proof that rejuvenation has occurred when using these therapies. This means various measures of functional age and health are required, and these measures should be something the research community as a whole agree upon as being suitable.

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