USC scientists have developed a wearable system that enables more natural and emotionally engaging interactions in shared digital spaces, opening new possibilities for remote work, education, health care and beyond.
Touch plays a vital role in how humans communicate and bond. From infancy through adulthood, physical contact helps foster emotional bonds, build trust and regulate stress. Yet in today’s increasingly digital world, where screens mediate many of our relationships, it is often missing.
To bridge the gap, researchers at the USC Viterbi School of Engineering have developed a wearable haptic system that lets users exchange physical gestures in virtual reality and feel them in real time, even when they’re miles apart. Their paper is published on the arXiv preprint server.
Although lithium is highly effective in treating bipolar disorder, the chemical has a narrow therapeutic window—too high a dose can be toxic to patients, causing kidney damage, thyroid damage, or even death, while too low a dose renders the treatment ineffective.
The dose of lithium varies between individuals based on body weight, diet, and other physiological factors, and requires regular measurement of lithium levels in the blood. Currently, this is only available through standard laboratory-based blood draws, which can be time-consuming, inconvenient, and painful. This makes personalized and easily-accessible lithium monitoring an important goal in the treatment for bipolar disorder.
“Our goal was to create an easy-to-use sensor that bypasses the need for blood draws entirely,” explained Yasser Khan, a USC Ming Hsieh Department of Electrical and Computer Engineering professor who leads the USC Khan Lab, and part of the USC Institute for Technology and Medical Systems (ITEMS), a joint initiative of USC Viterbi School of Engineering and Keck School of Medicine of USC focusing on innovative medical devices.
Precision and personalized medicine for disease management necessitates real-time, continuous monitoring of biomarkers and therapeutic drugs to adjust treatment regimens based on individual patient responses. This study introduces a wearable Microneedle-based Continuous Biomarker/Drug Monitoring (MCBM) system, designed for the simultaneous, in vivo pharmacokinetic and pharmacodynamic evaluation for diabetes. Utilizing a dual-sensor microneedle and a layer-by-layer nanoenzyme immobilization strategy, the MCBM system achieves high sensitivity and specificity in measuring glucose and metformin concentrations in skin interstitial fluid (ISF). Seamless integration with a smartphone application enables real-time data analysis and feedback, fostering a pharmacologically informed approach to diabetes management. The MCBM system’s validation and in vivo trials demonstrate its precise monitoring of glucose and metformin, offering a tool for personalized treatment adjustments. Its proven biocompatibility and safety suit long-term usage. This system advances personalized diabetes care, highlighting the move towards wearables that adjust drug dosages in real-time, enhancing precision and personalized medicine.
Real-time monitoring of drugs and biomarkers is essential for personalized diabetes care. Here, the authors present a wearable microneedle sensor system enabling simultaneous in vivo monitoring of glucose and metformin in interstitial fluids for personalized medicine.
The mechanical strength and toughness of engineering materials are often mutually exclusive, posing challenges for material design and selection. To address this, a research team from The Hong Kong Polytechnic University (PolyU) has uncovered an innovative strategy: by simply twisting the layers of 2D materials, they can enhance toughness without compromising material’s strength.
This breakthrough facilitates the design of strong and tough new 2D materials, promoting their broader applications in photonic and electronic devices. The findings have been published in Nature Materials.
While 2D materials often exhibit exceptional strength, they are extremely brittle. Fractures in materials are also typically irreversible. These attributes limit the use of 2D materials in devices that require repeated deformation, such as high-power devices, flexible electronics and wearables.
The world of wearable technology—such as sensors and energy-producing devices—is expanding, thanks to new research into a unique combination of materials that are flexible, safe to use on or inside the human body, and environmentally friendly.
Dr. Simon Rondeau-Gagné and a team of collaborators and graduate students have used the Canadian Light Source (CLS) at the University of Saskatchewan to show that semiconducting polymers and collagen—the main component of human skin—can be combined to create organic devices “that are more efficient, more conformable and specifically… more green as well.”
Collagen provided both the skin-like rigidity and elasticity (or bendability) the researchers were looking for in “a platform that can be integrated with something like the human body,” said Rondeau-Gagné, an associate professor in the Department of Chemistry and Biochemistry at the University of Windsor.
A new wearable wristband could significantly improve diabetes management by continuously tracking not only glucose but also other chemical and cardiovascular signals that influence disease progression and overall health. The technology was published in Nature Biomedical Engineering.
The flexible wristband consists of a microneedle array that painlessly samples interstitial fluid under the skin to measure glucose, lactate and alcohol in real time using three different enzymes embedded within the tiny needles. Designed for easy replacement, the microneedle array can be swapped out to tailor wear periods. This reduces the risk of allergic reactions or infection while supporting longer-term use.
Simultaneously, the wristband uses an ultrasonic sensor array to measure blood pressure and arterial stiffness, while ECG sensors measure heart rate directly from wrist pulses. These physiological signals are key indicators of cardiovascular risk, which is often elevated in people with diabetes but is rarely monitored continuously outside of a clinical setting.
Researchers have developed a first-of-its-kind wearable device capable of continuously scanning the lungs and heart of hospital patients while they rest in bed – offering a revolutionary alternative to CT scans.
The belt-like device, attached around a patient’s chest, uses ultrasound and works like a CT scanner. Rather than taking an isolated snapshot, it can produce a series of dynamic, high-resolution images of the heart, lungs and internal organs over time, giving doctors deeper insight into a patient’s condition. The device can be worn in bed and also reduces the need for repeated trips to radiology or exposure to doses of ionising radiation.
The breakthrough device has been developed at the University of Bath in collaboration with Polish technology company Netrix and is detailed in a recent publication in IEEE Transactions on Instrumentation and Measurement.
Groundbreaking sensor technology promises safer, real-time monitoring for hospitalised cardiothoracic patients.