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Archive for the ‘singularity’ category

Aug 18, 2022

Probing the Secrets to Human Longevity with Methuselah Flies

Posted by in categories: biotech/medical, genetics, life extension, robotics/AI, singularity

In the 1980s, biologist Dr Michael Rose started to selectively breed Drosophila fruit flies for increased longevity. Today, the descendants of the original Methuselah flies are held by biotech firm Genescient Corporation and live 4.5 times longer than normal fruit flies.

The flies’ increased lifespan is explained by a significant number of systemic genetic changes — but how many of these variations represent lessons that can be used to design longevity therapies for humans? Dr. Ben Goertzel and his bio-AI colleagues at SingularityNET and Rejuve. AI are betting the answer is quite a few.

SingularityNET and Rejuve. AI have launched a partnership with Genescient to apply advanced machine learning and machine reasoning methods to transfer insights gained from the Methuselah fly genome to the human genome. The goal is to acquire new information regarding gene therapies, drugs or nutraceutical regimens for prolonging healthy human life.

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Aug 17, 2022

PANTHEON Series | Official Trailer (HD) AMC

Posted by in category: singularity

A young woman begins receiving messages from an unknown number that claims to be her deceased father. Trying to uncover the truth, she stumbles upon a larger conspiracy involving the singularity. On AMC+, September 1.

CAST: Katie Chang, Paul Dano, Daniel Dae Kim, William Hurt, Maude Apatow, Rosemarie DeWitt, Aaron Eckhart, Taylor Schilling.

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Aug 16, 2022

The Holographic Principle, Quantum Mechanics, and Simulated Reality (SR)

Posted by in categories: alien life, bitcoin, cryptocurrencies, Elon Musk, existential risks, holograms, information science, quantum physics, robotics/AI, singularity, virtual reality

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Aug 15, 2022

FUTURIST | Most important ideas & concepts (5x) — Peter Joosten MSc

Posted by in categories: futurism, singularity

What are 5 important theories, ideas and/or concepts of futurists and future thinkers? What is the most important theory (in my opinion)?

Please leave a comment if you like the video or when you have a question!

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Aug 14, 2022

Human cognition-enhancing CORD7 mutation increases active zone number and synaptic release

Posted by in categories: biotech/medical, engineering, neuroscience, singularity

This article tells of possible way to increase brain intelligence through a certain mutation which in theory could be altered for biological singularity like effects in the future.


Humans carrying the CORD7 (cone-rod dystrophy 7) mutation possess increased verbal IQ and working memory. This autosomal dominant syndrome is caused by the single-amino acid R844H exchange (human numbering) located in the 310 helix of the C2A domain of RIMS1/RIM1 (Rab3-interacting molecule 1). RIM is an evolutionarily conserved multi-domain protein and essential component of presynaptic active zones, which is centrally involved in fast, Ca2+-triggered neurotransmitter release. How the CORD7 mutation affects synaptic function has remained unclear thus far. Here, we established Drosophila melanogaster as a disease model for clarifying the effects of the CORD7 mutation on RIM function and synaptic vesicle release.

To this end, using protein expression and X-ray crystallography, we solved the molecular structure of the Drosophila C2A domain at 1.92 Å resolution and by comparison to its mammalian homolog ascertained that the location of the CORD7 mutation is structurally conserved in fly RIM. Further, CRISPR/Cas9-assisted genomic engineering was employed for the generation of rim alleles encoding the R915H CORD7 exchange or R915E, R916E substitutions (fly numbering) to effect local charge reversal at the 310 helix. Through electrophysiological characterization by two-electrode voltage clamp and focal recordings we determined that the CORD7 mutation exerts a semi-dominant rather than a dominant effect on synaptic transmission resulting in faster, more efficient synaptic release and increased size of the readily releasable pool but decreased sensitivity for the fast calcium chelator BAPTA.

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Aug 5, 2022

Do ‘bouncing universes’ have a beginning?

Posted by in categories: singularity, space

In trying to understand the nature of the cosmos, some theorists propose that the universe expands and contracts in endless cycles.

Because this behavior is hypothesized to be perpetual, the should have no beginning and no end—only eternal cycles of growing and shrinking that extend forever into the future, and forever into the past.

It’s an appealing concept in part because it removes the need for a state called a singularity that corresponds to “beginning of time” in other models.

Aug 3, 2022

Is Artificial Sentience Here? with Blake Lemoine

Posted by in categories: robotics/AI, singularity

Recently, Blake Lemoine a computer scientist and machine learning bias researcher for Google released an interview with Google’s LaMDA a conversation technology and AI. Blake proposes, based on his time testing LaMDA, that it is a super intelligence and sentient. Blake details just what made him come to this conclusion and why he believes we have passed the singularity, last year.

Blake’s links:
https://twitter.com/cajundiscordian.
https://cajundiscordian.medium.com/is-lamda-sentient-an-interview-ea64d916d917

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Jul 30, 2022

2019 Recap: “Vernor Vinge on the Singularity”— (2 decades ago)

Posted by in categories: Elon Musk, ethics, existential risks, robotics/AI, singularity

By Natasha Vita-More.

Has the technological singularity in 2019 changed since the late 1990s?

As a theoretical concept it has become more recognized. As a potential threat, it is significantly written about and talked about. Because the field of narrow AI is growing and machine learning has found a place in academics and entrepreneurs are investing in the growth of AI, tech leaders have come to the table and voiced their concerns, especially Bill Gates, Elon Musk, and the late Stephen Hawking. The concept of existential risk has taken a central position within the discussions about AI and machine ethicists are prepping their arguments toward a consensus that near-future robots will force us to rethink the exponential advances in the fields of robotics and computer science. Here it is crucial for those leaders in philosophy and ethics to address the concept of what an ethical machine means and the true goal of machine ethics.

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Jul 30, 2022

On black holes, holography, the Quantum Extended Church-Turing Thesis, fully homomorphic encryption, and brain uploading

Posted by in categories: computing, cosmology, encryption, neuroscience, quantum physics, singularity

I promise you: this post is going to tell a scientifically coherent story that involves all five topics listed in the title. Not one can be omitted.

My story starts with a Zoom talk that the one and only Lenny Susskind delivered for the Simons Institute for Theory of Computing back in May. There followed a panel discussion involving Lenny, Edward Witten, Geoffrey Penington, Umesh Vazirani, and your humble shtetlmaster.

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Jul 28, 2022

#58 Dr. Ben Goertzel — Artificial General Intelligence

Posted by in categories: biological, blockchains, information science, neuroscience, physics, robotics/AI, singularity

Patreon: https://www.patreon.com/mlst.
Discord: https://discord.gg/ESrGqhf5CB

The field of Artificial Intelligence was founded in the mid 1950s with the aim of constructing “thinking machines” — that is to say, computer systems with human-like general intelligence. Think of humanoid robots that not only look but act and think with intelligence equal to and ultimately greater than that of human beings. But in the intervening years, the field has drifted far from its ambitious old-fashioned roots.

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