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Biological components are less reliable than electrical ones, and rather than instantaneously receive the incoming signals, the signals arrive with a variety of delays. This forces the brain to cope with said delays by having each neuron integrate the incoming signals over time and fire afterwards, as well as using a population of neurons, instead of one, to overcome neuronal cells that temporarily don’t fire.

The human brain’s remarkably prolonged development is unique among mammals and is thought to contribute to our advanced learning abilities. Disruptions in this process may explain certain neurodevelopmental diseases.

Now, a team of researchers led by Prof. Pierre Vanderhaeghen (VIB-KU Leuven), together with scientists of Columbia University and Ecole Normale Supérieure has discovered a link between two genes, present only in human DNA, and a key gene called SYNGAP1, which is mutated in intellectual disability and .

Their study, published in Neuron, provides a surprisingly direct link between human brain evolution and neurodevelopmental disorders.

Kyoto, Japan — Scanning your brain to decode the contents of your mind has been a subject of intense research interest for some time. As studies have progressed, scientists have gradually been able to interpret what test subjects see, remember, imagine, and even dream.

There have been significant limitations, however, beginning with a necessity to extensively catalog each subject’s unique brain patterns, which are then matched with a small number of pre-programmed images. These procedures require that subjects undergo lengthy and expensive fMRI testing.

Accidental Discovery in the Lab

The discovery happened unexpectedly during research on warty comb jellies (Mnemiopsis leidyi), also known as sea walnuts, in a lab at the University of Exeter. Researchers noticed that one jelly was missing from a tank, only to realize that a larger jelly was actually two individuals fused together. This accidental fusion occurred when the jellies sustained minor injuries. Excited by the finding, study lead author Kei Jokura immediately shared the discovery with other lab members.

The team then tested whether this fusion could be replicated. They injured 20 comb jellies by removing small sections of their bodies and placed them near each other. Out of the 20, nine pairs fused completely, typically within 24 hours. The merging process also affected their nervous systems, which synchronized rapidly. Researchers observed that the fused individuals reacted as one when poked, indicating a full integration of their neural functions.

Scientists discovered that the molecule CaMKII helps neurons encode information over seconds, a key process in learning. This challenges previous beliefs about how CaMKII influences synapse-specific plasticity.

A recent study from the Max Planck Florida Institute for Neuroscience, published in Nature, has uncovered a crucial step in how neurons encode information on timescales aligned with the process of learning.

A timing mismatch.

A BREAKTHROUGH cancer treatment “could be the cure” for a “death sentence” form of the disease after making tumours disappear.

The experimental approach has seen remarkable success in some brain cancer patients — with experts saying it could be available on the NHS within five years.

Can we in principle ever deduce the mental from the physical?

Christopher Devlin Brown and David Papineau have a new paper out in the Journal of Consciousness Studies titled: Illusionism and A Posteriori Physicalism; No Fact of the Matter. (Note: the link is to a free version.) As the title makes clear, the overall gist is that the difference between illusionism and a posteriori physicalism amounts to a definitional dispute.

A quick primer. Illusionism is the stance that consciousness exists, but only in the sense of functional capabilities such as modeling the self in its environment, attention, learning, episodic memory, self monitoring, etc. What’s thought to be illusory is phenomenal consciousness, the “what it’s like” nature of subjective experience, but particularly in the strong sense as something distinct from functional capabilities, and with properties, such as fundamental subjectivity, that imply it’s non-physical.