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Adopting a curious mindset over a high-pressure one can enhance memory, according to recent research from Duke University. The study showed that participants who envisioned themselves as a thief planning a heist in a virtual art museum demonstrated better recall of the paintings they encountered than those who imagined executing the heist on the spot while playing the same computer game.

The slight variation in motivations — the urgent need to achieve immediate goals versus the curious exploration for future objectives — could have significant implications in real-life scenarios. These include incentivizing people to receive a vaccine, prompting action against climate change, and potentially providing new treatments for psychiatric conditions.

The findings were recently published in the Proceedings of the National Academy of Sciences.

Humans have a distinctive skeleton, and are the only bipedal great apes (the great ape species are bonobos, chimpanzees, gorillas, orangutans, and humans). While the evolution of the human skeleton enabled us to walk upright, it also led to the rise of musculoskeletal disease. It’s thought that cognitive development began to accelerate in humans once we started to move around, adapt to new environments, and make use of tools. Researchers have now used advanced computational tools and a trove of human genetic data in the UK Biobank to outline the genetic changes that occurred as primates started to walk upright for the first time.

These findings, which were reported in Science, have suggested that natural selection had a strong influence on the genetic changes that altered our anatomy, and gave early humans an evolutionary leg up.

An international team led by investigators at McLean Hospital has analyzed the genes expressed in approximately 575,000 individual cells from the brains of people with and without post-traumatic stress and major depressive disorders (PTSD and MDD), revealing new insights into the mechanisms behind the brain’s stress response in these conditions.

The findings, which are published in The American Journal of Psychiatry, could lead to novel markers of PTSD and MDD and well as new therapeutic targets.

Because studies have implicated the dorsolateral prefrontal cortex (DLPFC) region of the brain in PTSD and MDD, the scientists compared the genes expressed in cells in DLPFC samples collected postmortem from 11 individuals with PTSD, 10 with MDD, and 11 without either of these conditions with a replication dataset half the size. The researchers detected which genes were expressed by which cells—including eight different types of cells—through a technique called single-cell RNA sequencing.

Scientists at the University of Colorado Anschutz Medical Campus have discovered what they believe to be the central mechanism behind cognitive decline associated with normal aging.

“The mechanism involves the mis-regulation of a brain protein known as CaMKII which is crucial for memory and learning,” said the study’s co-senior author Ulli Bayer, PhD, professor of pharmacology at the University of Colorado School of Medicine. “This study directly suggests specific pharmacological treatment strategies.”

The study was published today in the journal ‘Science Signaling.’

😗😁 This genetic trick could stop some brain disorders in humans with crispr.

The reshuffling of neurons during fruit fly metamorphosis suggests that larval memories don’t persist in adults.

Alfred North Whitehead’s Process Philosophy, the Mystery of Consciousness and the Mind-Body Problem (2016)
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Compilation by Michael Schramm.
Background Music by Michael Schramm.
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Speakers & Quotations:
Charles Birch, Susan Blackmore, David J. Chalmers, Daniel C. Dennett, Freeman Dyson, David Ray Griffin, Charles Hartshorne, Nicholas Humphrey, Christof Koch, Colin McGinn, Thomas Nagel, Karl R. Popper, John R. Searle, Rupert Sheldrake, Galen Strawson, Alfred North Whitehead.

Tags:
panpsychism, consciousness, mind-body problem, process philosophy, process metaphysics, materialism, (property) dualism, quantum physics, indeterminism, free will.
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I have uploaded the resource document again and added a new link. Thanks for the interest!
Resources (new link):
https://theology-ethics.uni-hohenheim.de/fileadmin/einrichtu…ources.pdf.
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How can we increase our lifespan by over two decades?

In this video, we dive into a comprehensive study involving over 700,000 U.S. veterans that reveals the immense power of eight healthy lifestyle habits.

Continue reading “Adding Decades to Your Life: The Power of Eight Healthy Habits — Neuroscience News” »

Cognitive dysfunction in aging is a major biomedical challenge. Whether treatment with klotho, a longevity factor, could enhance cognition in human-relevant models such as in nonhuman primates is unknown and represents a major knowledge gap in the path to therapeutics. We validated the rhesus form of the klotho protein in mice showing it increased synaptic plasticity and cognition. We then found that a single administration of low-dose, but not high-dose, klotho enhanced memory in aged nonhuman primates. Systemic low-dose klotho treatment may prove therapeutic in aging humans.

Scientists adding a human intelligence gene into monkeys — it’s the kind of thing you’d see in a movie like Rise of the Planet of the Apes. But Chinese researchers have done just that, improving the short-term memories of the monkeys in a study published in March 2019 in the Chinese journal National Science Review. While some experts downplayed the effects as minor, concerns linger over where the research may lead.

The goal of the work, led by geneticist Bing Su of Kunming Institute of Zoology, was to investigate how a gene linked to brain size, MCPH1, might contribute to the evolution of the organ in humans. All primates have some variation of this gene. However, compared with other primates, our brains are larger, more advanced and slower to develop; the researchers wondered whether differences that evolved in the human version of MCPH1 might explain our more complex brains.

Article from 2019

Continue reading “What Happens When Scientists Put a Human Intelligence Gene Into a Monkey?” »