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Archive for the ‘neuroscience’ category: Page 233

Aug 2, 2023

First comprehensive maps of infant brains reveal clues to neurodevelopment

Posted by in categories: mapping, neuroscience

Scientists have constructed a comprehensive set of functional maps of infant brain networks, providing unprecedented details on brain development from birth to two years old.

The infant brain cortex parcellation maps, published today in eLife, have already provided novel insights into when different brain functions develop during infancy and provide valuable, publicly available references for early brain developmental studies.

Cortical parcellation is a means of studying brain function by dividing up cortical gray matter in different locations into “parcels.” Scans from imaging (fMRI) are taken when the brain is in an inactive “resting” state, alongside measurements of brain connectivity, to study brain function within each parcel.

Aug 2, 2023

New study links brain waves directly to memory

Posted by in category: neuroscience

Neurons produce rhythmic patterns of electrical activity in the brain. One of the unsettled questions in the field of neuroscience is what primarily drives these rhythmic signals, called oscillations. University of Arizona researchers have found that simply remembering events can trigger them, even more so than when people are experiencing the actual event.

The researchers, whose findings are published in the journal Neuron, specifically focused on what are known as , which emerge in the ’s hippocampus region during activities like exploration, navigation and sleep. The hippocampus plays a crucial role in the brain’s ability to remember the past.

Prior to this study, it was believed that the played a more important role in driving theta oscillations, said Arne Ekstrom, professor of cognition and in the UArizona Department of Psychology and senior author of the study. But Ekstrom and his collaborators found that generated in the brain is the main driver of theta activity.

Aug 1, 2023

Study sheds light on where conscious experience resides in the brain

Posted by in categories: biotech/medical, neuroscience

Researchers from Hebrew University of Jerusalem and UC Berkeley recorded electrical activity in the brains of epilepsy patients while showing them various images in an attempt to find out where persistent images are stored in the brain and how we consciously access those images. (Image credit: Hadar Vishne, Royal College of Art)

More than a quarter of all stroke victims develop a bizarre disorder — they lose conscious awareness of half of all that their eyes perceive.

After a stroke in the brain’s right half, for example, a person might eat only what’s on the right side of the plate because they’re unaware of the other half. The person may see only the right half of a photo and ignore a person on their left side.

Aug 1, 2023

Innovative Liquid Cushioning Technology Promises Revolution in Safety Gear

Posted by in categories: biotech/medical, engineering, neuroscience, wearables

New breakthrough in material design will help football players, car occupants, and hospital patients.

A significant breakthrough in the field of protective gear has been made with the discovery that football players were unknowingly acquiring permanent brain damage from repeated head impacts throughout their professional careers. This realization triggered an urgent search for better head protection solutions. Among these innovations is nanofoam, a material found inside football helmets.

Thanks to mechanical and aerospace engineering associate professor Baoxing Xu at the University of Virginia and his research team, nanofoam just received a big upgrade and protective sports equipment could, too. This newly invented design integrates nanofoam with “non-wetting ionized liquid,” a form of water that Xu and his research team now know blends perfectly with nanofoam to create a liquid cushion. This versatile and responsive material will give better protection to athletes and is promising for use in protecting car occupants and aiding hospital patients using wearable medical devices.

Aug 1, 2023

AI Agents With ‘Multiple Selves’ Learn to Adapt Quickly in a Changing World

Posted by in categories: neuroscience, robotics/AI

So why not break the AI apart?

In a new study published in PNAS, the team took a page from cognitive neuroscience and built a modular AI agent.

The idea is seemingly simple. Rather than a monolithic AI—a single network that encompasses the entire “self”—the team constructed a modular agent, each part with its own “motivation” and goals but commanding a single “body.” Like a democratic society, the AI system argues within itself to decide on the best response, where the action most likely to yield the largest winning outcome guides its next step.

Aug 1, 2023

Rewriting Textbooks: Scientists Discover Unexpected Complexity of Cerebellar Connections

Posted by in categories: biotech/medical, neuroscience

Images of thousands of Purkinje cells reveal that almost all human cells have multiple primary dendrites. These structures, when observed in mice, facilitate connections with multiple climbing fibers originating from the brain stem.

In 1906, the Spanish researcher Santiago Ramón y Cajal received the Nobel Prize for his trailblazing exploration of the microscopic structures of the brain. His renowned illustrations of Purkinje cells within the cerebellum depict a forest of neuron structures, with multiple large branches sprouting from the cell body and splitting into beautiful, leaf-like patterns.

Despite these early portrayals showing multiple dendrites branching out from the cell body, the enduring consensus among neuroscientists is that Purkinje cells possess only a single main dendrite that forms a connection with a lone climbing fiber originating from the brain stem. However, a recent study from the University of Chicago, recently published in the journal Science, reveals that Cajal’s sketches were indeed accurate — practically all Purkinje cells in the human cerebellum have multiple primary dendrites.

Aug 1, 2023

Psilocybin helps to alleviate cognitive deficits in an animal model of stress-induced depression, study finds

Posted by in categories: biotech/medical, neuroscience

Psilocybin has antidepressant-like effects and can improve cognitive function in a rat model of depression induced by chronic stress, according to new research published in Psychedelic Medicine. The findings provide new insights into the potential therapeutic applications of psychedelic substances and highlight the need for further research in this area to fully comprehend the underlying mechanisms.

Psilocybin is a naturally occurring psychedelic compound found in certain species of mushrooms, often referred to as “magic mushrooms” or “shrooms.” In recent years, there has been a growing interest in studying psilocybin and other psychedelics for their potential therapeutic effects. Psychedelics have shown promising rapid and persistent antidepressant effects in humans and animals. However, the exact mechanism behind these effects is not fully understood.

To investigate the cellular and molecular mechanisms responsible for the antidepressant effects of psychedelics, the researchers used an appropriate animal model of depression. They chose a chronic stress-based model for greater translational value, as chronic stress is known to be a significant factor in depression. They specifically focused on female rats, as women are more susceptible to depression than men.

Aug 1, 2023

We May Have Found The Part of The Brain Where Conscious Experience Lives

Posted by in category: neuroscience

New research sheds light on a tricky idea of consciousness: There’s a difference between what the brain takes in and what we’re consciously aware of taking in.

Scientists now think they’ve pinpointed the brain region where that conscious awareness is managed.

The team, from the Hebrew University of Jerusalem in Israel and the University of California, Berkeley (UC Berkeley), in the US, found sustained brain activity in the occipitotemporal area of the visual cortex in the back of the brain.

Aug 1, 2023

Golgi apparatus may play a role in neuronal circuit reorganization during postnatal brain development

Posted by in categories: chemistry, neuroscience

Neurons are the cells that constitute neural circuits and use chemicals and electricity to receive and send messages that allow the body to do everything, including thinking, sensing, moving, and more. Neurons have a long fiber called an axon that sends information to the subsequent neurons. Information from axons is received by branch-like structures that fan out from the cell body, called dendrites.

Dendritic refinement is an important part of early postnatal brain development during which dendrites are tailored to make specific connections with appropriate axons. In a recently published paper, researchers present evidence showing how a mechanism within the neurons of a rodent involving the Golgi apparatus initiates dendritic refinement with the help of the neuronal activity received by a receptor of a neurotransmitter called N-methyl-D-aspartate-type glutamate receptor (NMDAR).

The paper was published in Cell Reports on July 28.

Aug 1, 2023

Distinct ventral stream and prefrontal cortex representational dynamics during sustained conscious visual perception

Posted by in category: neuroscience

How is ongoing visual experience represented neurally? Vishne et al. decode images lasting different durations from intracranial electrophysiology, uncovering distinct representation dynamics across the human brain: sustained and stable in occipitotemporal cortex and transient in frontoparietal areas. This sheds light on the spatiotemporal correlates of experience encoding by the brain.