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Archive for the ‘neuroscience’ category: Page 112

Apr 4, 2024

World’s most powerful MRI machine captures first stunning brain scans

Posted by in categories: biotech/medical, neuroscience

The world’s most powerful MRI machine has started proving its worth, by scanning living human brains. The resulting images give an ultra high resolution glimpse into the brain, which will help us better understand the nature of consciousness and treat neurodegenerative diseases.

Developed by the French Alternative Energies and Atomic Energy Commission (CEA), the Iseult MRI machine packs a magnetic field strength of 11.7 Teslas (T). By comparison, conventional MRI machines in wide use in hospitals today are usually 1.5 or at most 3 T.

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Apr 4, 2024

Fpsyg-12–749868 (1).Pdf

Posted by in category: neuroscience

Global workspace theory of consciousness.


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Apr 4, 2024

Risk Factors For Faster Brain Aging

Posted by in categories: biotech/medical, education, genetics, life extension, neuroscience

Recent research published in Nature Communications from the Nuffield Department of Clinical Neurosciences at the University of Oxford has identified 15 modifiable risk factors for dementia, and of those diabetes, alcohol intake, and traffic-related air pollution are the most harmful.

Previous research from this group revealed an area of weakness in the brain of a specific network of higher-order regions that only develop later in adolescence but also display earlier degeneration in old age, and they showed that this brain network is particularly vulnerable to Alzheimer’s disease and schizophrenia. This study investigated genetic and modifiable influences on these regions by utilizing data from the UK Biobank.

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Apr 4, 2024

New treatments in sight for challenging neuropsychiatric symptoms in neurodegenerative diseases

Posted by in categories: biotech/medical, neuroscience

🧠💊🔬


Study reviews the advancements in pharmacological treatments for neuropsychiatric syndromes in neurodegenerative disorders, discussing the complexities of managing symptoms such as depression, disinhibition, apathy, psychosis, and agitation to improve patient care.

Apr 4, 2024

Immunotherapy Shows Promise as Alzheimer’s Treatment

Posted by in categories: biotech/medical, neuroscience

Summary: Researchers unveiled a novel approach to combat Alzheimer’s disease by activating microglia, the brain’s immune cells, to devour amyloid beta plaques, a hallmark of the condition. This study highlights the potential of using immunotherapy to not only tackle Alzheimer’s but also other neurodegenerative diseases characterized by harmful protein accumulations.

The team’s method involves using an antibody to stimulate microglia into clearing these plaques, offering a promising alternative to current treatments that directly target amyloid beta and might cause side effects like ARIA. This breakthrough paves the way for new therapeutic strategies that harness the immune system to fight the devastating effects of Alzheimer’s and possibly other diseases like Parkinson’s and ALS.

Apr 3, 2024

Neural feedback loops algorithms and consciousness

Posted by in categories: information science, neuroscience

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Apr 3, 2024

Frontiers: Information processing in neural systems can be described and analyzed at multiple spatiotemporal scales

Posted by in category: neuroscience

Generally, information at lower levels is more fine-grained but can be coarse-grained at higher levels. However, only information processed at specific scales of coarse-graining appears to be available for conscious awareness. We do not have direct experience of information available at the scale of individual neurons, which is noisy and highly stochastic. Neither do we have experience of more macro-scale interactions, such as interpersonal communications. Neurophysiological evidence suggests that conscious experiences co-vary with information encoded in coarse-grained neural states such as the firing pattern of a population of neurons. In this article, we introduce a new information al theory of consciousness: Information Closure Theory of Consciousness (ICT). We hypothesize that conscious processes are processes which form non-trivial information al closure (NTIC) with respect to the environment at certain coarse-grained scales. This hypothesis implies that conscious experience is confined due to information al closure from conscious processing to other coarse-grained scales. Information Closure Theory of Consciousness (ICT) proposes new quantitative definitions of both conscious content and conscious level. With the parsimonious definitions and a hypothesize, ICT provides explanations and predictions of various phenomena associated with consciousness. The implications of ICT naturally reconcile issues in many existing theories of consciousness and provides explanations for many of our intuitions about consciousness. Most importantly, ICT demonstrates that information can be the common language between consciousness and physical reality.

Imagine you are a neuron in Alice’s brain. Your daily work is to collect neurotransmitters through dendrites from other neurons, accumulate membrane potential, and finally send signals to other neurons through action potentials along axons. However, you have no idea that you are one of the neurons in Alice’s supplementary motor area and are involved in many motor control processes for Alice’s actions, such as grabbing a cup. You are ignorant of intentions, goals, and motor plans that Alice has at any moment, even though you are part of the physiological substrate responsible for all these actions. A similar story also happens in Alice’s conscious mind. To grab a cup, for example, Alice is conscious of her intention and visuosensory experience of this action. However, her conscious experience does not reflect the dynamic of your membrane potential or the action potentials you send to other neurons every second.

Apr 3, 2024

A new computational technique could make it easier to engineer useful proteins

Posted by in categories: biotech/medical, computing, genetics, neuroscience

To engineer proteins with useful functions, researchers usually begin with a natural protein that has a desirable function, such as emitting fluorescent light, and put it through many rounds of random mutation that eventually generate an optimized version of the protein.

This process has yielded optimized versions of many important proteins, including green fluorescent protein (GFP). However, for other proteins, it has proven difficult to generate an optimized version. MIT researchers have now developed a computational approach that makes it easier to predict mutations that will lead to better proteins, based on a relatively small amount of data.

Using this model, the researchers generated proteins with mutations that were predicted to lead to improved versions of GFP and a protein from adeno-associated virus (AAV), which is used to deliver DNA for gene therapy. They hope it could also be used to develop additional tools for neuroscience research and medical applications.

Apr 3, 2024

Ever Wanted a Brain Transplant? Here Are The Challenges We Face

Posted by in categories: biotech/medical, neuroscience

The neurosurgeon Sergio Canavero announced in 2015 that he could soon be capable of performing the world’s first human head transplant procedure. This would mean that it would be possible to remove someone’s head, and graft it onto the neck and shoulders of another person. As of yet, this has only been performed on cadavers and not on living humans.

But suppose you want to keep the face that you’ve already got? Or have grown tired of the body you inhabit? Could it ever be possible to switch brains between bodies instead?

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Apr 3, 2024

Webb telescope detects light from an Earth-like planet

Posted by in categories: biotech/medical, computing, neuroscience

The brain computer interface (BCI) device can be used by inexperienced patients to play games within just a few sessions.

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