Lifeboat Foundation

We are doing a series of articles that discuss the Hallmarks of Aging. Published in 2013, this paper is highly regarded in academia and is one of the most cited papers in biology, with an average of being cited once every two days. The paper divides aging into distinct categories (“hallmarks”) of damage to explain how the aging process works and how it causes age-related diseases[1].

Today, we will be looking at one of the primary hallmarks, genomic instability.

They made their money by harnessing tech to transform life. Now, they want to use their wealth to extend the limits of life. Longevity is the new frontier for these Silicon Valley barons and they hope to again do what they do best, transform life as we know it and make a killing off it.

Recorded Oct 4th, 2017

Link to the interview, goo.gl/8rQ6YS

Continue reading “Aubrey de Grey, Ph.D.: Rejuvenation biotechnology: Why Age May Soon Not Mean Aging” »

We want to hear your story too! https://www.leafscience.org/longevity-month-2017-tell-us-your-story/

The work, published in the March 8 issue of Science, finally proves that a single anti-aging enzyme in the body can be targeted, with the potential to prevent age-related diseases and extend lifespans.

The paper shows all of the 117 drugs tested work on the single enzyme through a common mechanism. This means that a whole new class of anti-aging drugs is now viable, which could ultimately prevent cancer, Alzheimer’s disease and type 2 diabetes.

“Ultimately, these drugs would treat one disease, but unlike drugs of today, they would prevent 20 others,” says the lead author of the paper, Professor David Sinclair, from UNSW Medicine, who is based at Harvard University. “In effect, they would slow aging.”

Continue reading “Anti-aging drug breakthrough” »

MouseAge (https://www.lifespan.io/mouseage) is creating the first photographic biomarker system using the power of artificial intelligence.

The goal of MouseAge is to create a system capable of determining the age of mice without the need for invasive or even harmful tests.

Continue reading “MouseAge: Visual Biomarker for Mouse Aging” »

There’s no doubt that Dr. Ilia Stambler’s Longevity promotion: multidisciplinary perspective is a great book for the advocate and keen supporter of healthy life extension. Check out our review by Nicola Bagalà.

There’s no doubt that Dr. Ilia Stambler’s Longevity promotion: multidisciplinary perspective is a thorough book that all kinds of advocates of healthy longevity may find very useful. The book reads pretty much like a collection of academics papers, each dealing with a different aspect of the matter, including science, history, social and moral implications, legislation, and advocacy. Just like you would expect from an academic work, each section of this book is complete with exhaustive sources that will indubitably prove helpful should you wish to dig deeper into the topic being discussed.

The first section of the book focuses on advocacy, discussing typical concerns raised in the context of life extension, outreach material, and initiatives, and it offers suggestions for effective policies to promote aging and longevity research. The latter part of this section was one of the hardest for me to read since policies and legislation are not at all my strongest suit, but I do believe that professional lobbyists and advocates who have legal and regulatory backgrounds and wish to take action will find numerous ideas in it.

Continue reading “Book Review: Longevity Promotion a Multidisciplinary Perspective” »

The cure for aging is coming

Perpetual Life