Lifeboat Foundation

In this episode, Dr. David Sinclair and co-host Matthew LaPlante discuss why we age. In doing so, they discuss organisms that have extreme longevity, the genes that control aging (mTOR, AMPK, Sirtuins), the role of sirtuin proteins as epigenetic regulators of aging, the process of “ex-differentiation” in which cells begin to lose their identity, and how all of this makes up the “Information Theory of Aging”, and the difference between “biological age” and “chronological age” and how we can measure biological age through DNA methylation clocks. #Aging #DavidSinclair #Longevity

In this week’s episode, Dr. David Sinclair and co-host Matthew LaPlante zero in on drugs and supplements that have been reported to combat aspects of aging. They share the latest experimental and clinical data for NAD boosters (these being NR, NMN, NAD IV drips and shots), resveratrol, fisetin, quercetin, rapamycin, spermidine, metformin, and berberine.

I describe the mechanisms by which different wavelengths of light impact the cells, tissues and organs of the human body, and how specifically timed light exposure of specific wavelengths can be used to improve sleep, enhance alertness, modulate hormone levels, and improve mood. I also explain the use of ultraviolet and infrared phototherapies to relieve pain increase testosterone and estrogen levels; improve skin health, appearance and wound healing; and how red light can be used to offset age-related vision loss and provide neuroprotection. Throughout the episode, I describe the mechanisms of light-based therapies and actionable tools that people can use positively impact mental and physical health.

The concept of biological immortality challenges the belief that death gives meaning to life and raises questions about the potential societal implications and ethical considerations of living indefinitely.

Questions to inspire discussion.

Continue reading “Biological Immortality by 2030: Implications & Predictions” »

I like the chapter “would you want to be”.

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Continue reading “Why Do Humans Grow Old?” »

Biotech company Teal Omics founded after researchers develop algorithm that measures how fast individual organs are aging.

ALBERT LEA, Minnesota (WCCO) — Living to 100 may seem like a major feat, but there are communities around the world where it’s common — they’re called “Blue Zones.”

Minnesota native Dan Buettner is one of the foremost experts on how they work. Buettner’s new Netflix documentary and New York Times bestsellers reveal the secret recipe to longevity.

XPRIZE founder Peter Diamandis on the biggest prize the world has ever seen – and why a successful outcome will mean we’ll all be winners.

Aging | doi:10.18632/aging.204896. Jae-Hyun Yang, Christopher A. Petty, Thomas Dixon-McDougall, Maria Vina Lopez, Alexander Tyshkovskiy, Sun Maybury-Lewis, Xiao Tian, Nabilah Ibrahim, Zhili Chen, Patrick T. Griffin, Matthew Arnold, Jien Li, Oswaldo A. Martinez, Alexander Behn, Ryan Rogers-Hammond, Suzanne Angeli, Vadim N. Gladyshev, David A. Sinclair.