Lifeboat Foundation

Sometimes, people laugh imagining themselves as elderly people. Would they laugh imagining themselves as diseased?

If you watched a TV show, or read a comic book, where the difficulties and suffering of an oncological patient were portrayed in a disrespectful, humorous way, you would likely be outraged; at the very least, you would think that the show or comic book was in seriously bad taste. You’d probably think the same about similar material involving a disabled person or anyone who, because of an incurable disease, had only a short time to live spent in increasing misery—for example, a child affected by progeria, a disease that may best be described as a sort of accelerated aging syndrome that kills off its victims in their mid-twenties at the very latest.

Yet, it is not uncommon to see the diseases of old age, and even elderly people in general, being laughed at in just such a way without causing much outrage at all. Why is there a difference?

Continue reading “Aging is no laughing matter” »

As April ends and, at least in the Northern Hemisphere, summer approaches, let’s have a look at the progress of worldwide efforts to extend the summer of life.

Kazan 2018: Interventions to Extend Healthspan and Lifespan

The highlight of April was unquestionably the Interventions to Extend Healthspan and Lifespan Conference, which was held in Kazan, Russia on April 23–26. Featuring over 40 distinguished speakers from the field of aging research, this conference, which was the fifth in the series, included talks on epigenetics, genomics, metabolomics, aging biomarkers, bioinformatics, effective advocacy, and more. LEAF board director Elena Milova attended the event and had the chance to interview several of the experts present, such as Dr. Andrei Gudkov and Professor David Gems. We will publish more interviews of these speakers in the coming weeks, so stay tuned!

Elena Milova was at the Interventions to extend healthspan and lifespan 2018 conference in Kazan this week. This is an important conference in the aging research field, and it includes a variety of leading experts giving talks about their research. During the event, Elena had the opportunity to talk with professor David Gems about his work and his views on aging.

Professor Gems is a British geneticist and biogerontologist. He is Professor of Biology of Ageing at University College London, where he is also Deputy Director of the Institute of Healthy Ageing. His work focuses on understanding aging through the genetics of the nematode worm C. elegans.

https://www.uqpower.com.au/podcast/spotlight-on-ira-pastor-genetic-regeneration

But that’s not the only reason robots are big here. It also has a lot to do with an aging and declining population.

“Japan is a strange, exotic and quirky place” — but that’s not the only reason it’s on the leading edge of a robot revolution.

Klotho increased intelligence helps you regenerate muscle is an anti-aging and health-promoting significantly enhances our antioxidant balance.

Klotho is a protein that can make you more intelligent and live longer. Read on about how to increase it.

If you want to interpret your genes, you can use SelfDecode.

Continue reading “How to Increase Klotho (Protein) + Gene Associations” »

Today, we have a new study showing that a common, plant-based compound could help clear out unwanted senescent cells, which accumulate with age and produce inflammatory signals that drive age-related disease progression.

Taking out the trash

A new study has investigated a natural, plant-based compound for its ability to destroy senescent cells [1]. These cells accumulate with age due to the aging immune system becoming increasingly poor at removing them; this leads to a build-up of these cells and the secretions they produce, which cause chronic inflammation. These proinflammatory secretions are known as the senescence-associated secretory phenotype (SASP).

Continue reading “Goldenrod Extract has a Marginal Senolytic Effect in Cell Culture Study” »

CGP Grey has produced a new video, this time an animated version of Prof. Nick Bostrom’s “The Fable of the Dragon-Tyrant”. The fable is a powerful metaphor for aging and the acceptance mechanisms that have led humans to schedule their entire lives around its diktat.

There’s a good chance that ten or fifteen years from now, we’ll look back at this moment in history and realize that we were living through the beginning of a revolution, the first baby steps of what would eventually become a global movement. Maybe it’ll take longer, but just like it was for human flight, the unmistakable signs of the upcoming paradigm shift are all around us.

Continue reading “CGP Grey: The Fable of the Dragon-Tyrant” »

The enzyme holds clues to a possible cure for aging or potential cancer therapies.

Janet Iwasa

Nothing in your body lasts forever. Every single cell in your body will die eventually, and eventually you’ll run out of replacements. When that happens, various parts of your body will stop working correctly, and at some point the whole thing will shut down. Aging happens to all of us, and there’s nothing we can do about it.

Continue reading “Scientists Get Their First Look at the Enzyme That Could Help Battle Aging” »