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Archive for the ‘life extension’ category: Page 4

Oct 13, 2020

Higher doses of vitamin D slowed progression of frailty in older mice, preclinical study shows

Posted by in categories: biotech/medical, life extension

When it comes to vitamin D, most adults exhibit either frank deficiency, which results in clear clinical symptoms, or insufficiency, which often goes undetected. But how that insufficiency impacts physical health and the vulnerability of older adults to frailty as they age has been difficult to determine.

Now a University at Buffalo study of 24–28–month-old mice, the equivalent of 65-to-80-year-old adults, has found that can be slowed with what might be considered “over” supplementation with vitamin D, referred to as “hypersufficiency.”

Published Sept. 30 in Nutrients, the research builds on previous work that Kenneth L. Seldeen, Ph.D., first author and research assistant professor in the Department of Medicine in the Jacobs School of Medicine and Biomedical Sciences at UB, has been conducting for more than a decade with colleague Bruce R. Troen, MD, professor of medicine and chief of the Division of Geriatrics and Palliative Medicine and director of the Center for Successful Aging, both in the Jacobs School.

Oct 13, 2020

Research team discovers mechanism that restores cell function after genome damage

Posted by in categories: biotech/medical, life extension

Gets advanced, but some might like.


A research team from Cologne has discovered that a change in the DNA structure—more precisely in the chromatin—plays a decisive role in the recovery phase after DNA damage. The key is a double occupation by two methyl groups on the DNA packaging protein histone H3 (H3K4me2). The discovery was made by scientists under the direction of Prof. Björn Schumacher of the Cluster of Excellence for Aging Research CECAD, the Center for Molecular Medicine Cologne (CMMC), and the Institute for Genome Stability in Aging and Disease at the University of Cologne. The specific change enables genes to be reactivated and proteins to be produced after damage: The cells regain their balance and the organism recovers. The protective role of H3K4me2 was identified in experiments with the nematode Caenorhabditis elegans. The study has now been published in the journal Nature Structural & Molecular Biology.

The genome in every human cell is damaged on a daily basis, for example in the skin by UV radiation from the sun. Damage to the DNA causes diseases such as cancer, influences development, and accelerates aging. Congenital malfunctions in DNA repair can lead to extremely accelerated aging in rare hereditary diseases. Therefore, preservation and reconstruction processes are particularly important to ensure development and to maintain tissue function. DNA, which is rolled up on packaging proteins—the histones—like on cable drums, is regulated by methyl groups. Various proteins are responsible for placing methyl groups on histones or removing them. The number of groups on the packaging proteins affects the activity of genes and thus the production of the cell.

Continue reading “Research team discovers mechanism that restores cell function after genome damage” »

Oct 11, 2020

Sipping from the Fountain of Youth: Anti-Aging Treatments Explained By BioViva’s Elizabeth Parrish

Posted by in categories: biotech/medical, life extension

Our Website: https://www.findinggeniuspodcast.com/

Subscribe and review our Podcast on iTunes: https://apple.co/2L6tN88

Continue reading “Sipping from the Fountain of Youth: Anti-Aging Treatments Explained By BioViva’s Elizabeth Parrish” »

Oct 11, 2020

RAADfest 66 minute version for COPL

Posted by in categories: biotech/medical, genetics, life extension

I will be 49 tomorrow. I always like to find some sort of life extension vid for my birthday. And boy did I hit it. Here comes Bill Faloon to drown you in info. Fruit flies 48% increase at 4:30, George Church at 9:00, C. Elegans 5X increase 15:30, 114 year old blood cells reprogrammed ti pluripotent at 18:40, epigenetics at 22:30, Senile plasma at 24:30, Dr Mike West 4 paragraphs to summarize at 21:00, 44:00 minutes is Vitality in Aging Interventions Trail which anyone can join. Enjoy.

Oct 9, 2020

Can we resurrect the dead? Researchers catalogue potential future methods

Posted by in categories: cryonics, life extension, time travel, transhumanism

Alexey Turchin and Maxim Chernyakov, researchers belonging to the transhumanism movement, wrote a paper outlining the main ways technology might someday make resurrection possible.


From cryonics to time travel, here are some of the (highly speculative) methods that might someday be used to bring people back to life.

Oct 8, 2020

Some Fish Can Regenerate Their Eyes. Turns Out, Mammals Have Those Genes Too

Posted by in categories: bioengineering, biotech/medical, life extension

Perhaps in the future, gene editing may allow retinal regeneration in humans to reverse age-related vision deterioration.


Damage to the retina is the leading cause of blindness in humans, affecting millions of people around the world. Unfortunately, the retina is one of the few tissues we humans can’t grow back.

Unlike us, other animals such as zebrafish are able to regenerate this tissue that’s so crucial to our power of sight. We share 70 percent of our genes with these tiny little zebrafish, and scientists have just discovered some of the shared genes include the ones that grant zebrafish the ability to grow back their retinas.

Continue reading “Some Fish Can Regenerate Their Eyes. Turns Out, Mammals Have Those Genes Too” »

Oct 7, 2020

Volcanic eruption turned man’s brain into glass, ‘froze’ brain cells 2,000 years ago, scientists find

Posted by in categories: bioengineering, biotech/medical, life extension, neuroscience

Although it’s clearly NOT the approach taken for ultracold vitrification of patients undergoing life extension cryonization. (ULTRA🥶COLD being the exact opposite of ULTRA-BLOODY-H🥵T, obviously!)

Still, given the vast number of scientific and engineering discoveries and creations born on the backs of unexpected results, accidental discoveries, and outright screw up, it might have very useful data that has practical applications that would never otherwise have even been considered.


Italian scientists found intact brain cells in a man who was killed during the eruption of Mount Vesuvius in 79 AD.

Continue reading “Volcanic eruption turned man’s brain into glass, ‘froze’ brain cells 2,000 years ago, scientists find” »

Oct 6, 2020

Liz Parrish online talk during RAADfest 2020

Posted by in categories: biotech/medical, life extension

Watch Liz Parrish’s talk given on Sunday October 4, 2020, during the celebration of the annual event “Revolution Against Aging and Death Festival” (RAADfest 2020).

During her presentation Liz describes for the first time what BioViva Sciences and its exclusive partner Integrated Health Systems (IHS), are doing on the fronts of 1) Patient Access: 2) Research & Development and 3) Data Science.

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Oct 6, 2020

Genetic Factor Discovery Enables Adult Skin to Regenerate Like a Newborn Baby’s

Posted by in categories: biotech/medical, genetics, life extension

A newly identified genetic factor allows adult skin to repair itself like the skin of a newborn babe. The discovery by Washington State University researchers has implications for better skin wound treatment as well as preventing some of the aging process in skin.

In a study, published in the journal eLife on September 29, 2020, the researchers identified a factor that acts like a molecular switch in the skin of baby mice that controls the formation of hair follicles as they develop during the first week of life. The switch is mostly turned off after skin forms and remains off in adult tissue. When it was activated in specialized cells in adult mice, their skin was able to heal wounds without scarring. The reformed skin even included fur and could make goosebumps, an ability that is lost in adult human scars.

“We were able to take the innate ability of young, neonatal skin to regenerate and transfer that ability to old skin,” said Ryan Driskell, an assistant professor in WSU’s School of Molecular Biosciences. “We have shown in principle that this kind of regeneration is possible.”

Continue reading “Genetic Factor Discovery Enables Adult Skin to Regenerate Like a Newborn Baby’s” »

Oct 5, 2020

A Thai scientist and his family decide to cryonically freeze their cherished, dying toddler

Posted by in categories: cryonics, education, life extension

This heartfelt documentary follows their journey.

Subscribe: https://bit.ly/39caHHE

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