Lifeboat Foundation

Here at LEAF, we engage in a wide range of activities in support of the development of rejuvenation biotechnology in order to end age-related diseases. We report the latest news in aging research, attend conferences and give talks, educate, advocate, and fundraise for research projects on Lifespan.io; recently, we implemented the Longevity Investor Network in order to bring startup companies and investors together.

The Longevity Investor Network

The Longevity Investor Network is a group of investors who meet every month and invite young biotech companies working on aging to pitch their ideas. A successful pitch can often mean funding for a new startup company, helping to get its product developed and into clinical trials.

Continue reading “Bioquark Inc. — Real Bodies Milano Exhibit — Ira Pastor” »

Scientists found out that nonclassical monocites can become senescent.

Scientists from the A*STAR Singapore Immunology Network have discovered that immune cells called nonclassical monocytes undergo cellular senescence, contradicting what was previously thought of them [1].

Abstract

Continue reading “Type of Human Monocytes Found to Undergo Senescence” »

Today, we are going to be taking a look at GAIM and what it might mean for treating amyloid-based diseases, such as Alzheimer’s, Parkinson’s, and amyloidosis. This approach has the potential to treat multiple age-related diseases at once by targeting a common characteristic that they all share.

Misfolded proteins cause multiple age-related diseases

Proteins are large, complex molecules that regulate almost everything in our bodies, either directly or indirectly. They do the majority of the work in cells and are critical for the function, regulation, and structure of tissues and organs.

Faloon talking about the current state of the war on aging.

New research has revealed that fisetin – a natural flavonoid found in many fruits and vegetables – functions as an effective senolytic agent by clearing out damaged aging cells, improving health and extending lifespan.

Recently, we have shown that by administering the NAD+ precursor NMN (Nicotinamide Mononucleotide)in normal drinking water to older mice, NAD+ levels were restored to those normally associated with younger healthy animals. By administering NMN to mice for just one week, our lab demonstrated a robust correction in age-associated metabolic dysfunction and restored muscle mitochondrial function in old mice to levels seen in younger control mice (Gomes et al. 2013).

https://www.lifespan.io/campaigns/can-nmn-increase-longevity…019dfcda6c

Continue reading “Can supplementation with NMN Increase Longevity?” »

Dr. Aubrey De Grey, SENS Foundation, Co-Founder, talks of species that live hundreds of years. We have to understand metabolism and postpone old age.

How can reverse aging by improving repair mechanism. Cells die, and the waste as well as energy byproducts to avoid tissue breakdown with methyl donors.

Continue reading “Can we live long enough to live forever? Can we discover Immortality? Dr. Aubrey De Grey” »

The first of a series of info-nugget videos covering aging research. Today is a brief summary of aging.

For more aging research and news check out: https://www.leafscience.org/