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Hydrogen production with artificial photosynthesis and polymers

German scientists are researching a method to produce hydrogen using light and photoactive compounds on an organic chemical basis.


Hydrogen is considered to be one of the alternative energy sources of the future. So far, however, the costly and energy-intensive production process has been a major problem with regard to the environmental friendliness of this substance, which is in itself CO2 neutral. For this reason, increasing numbers of scientists around the world are researching other methods of producing hydrogen: from algae, for example. (IO reported). Scientists in Germany at the Friedrich Schiller University, the Leibniz Institute for Photonic Technologies (Leibniz IPHT) and the University of Ulm have taken inspiration from nature for their method of producing hydrogen.

To do so, the team from the “CataLight” Collaborative Research Center at the Universities of Jena and Ulm has combined new organic dyes with non-precious metal catalyst molecules that release gaseous hydrogen in water when irradiated with light. This substitute has shown a remarkable impact in terms of longevity and effect after excitation by visible light, they write in their study, published in Chemistry – A European Journal.

Photosynthesis as inspiration

In nature, sunlight is most effectively stored in chemical bonds through photosynthesis, because the light-collecting and reactive complexes in the thylakoid membrane are fixed in chloroplasts. The researchers led by Prof. Felix Schacher have achieved this type of arrangement with the help of polymers that interact with both hydrophilic and hydrophobic substances. These charged, so-called graft copolymers are produced artificially.

Microbial Products Affect the Hallmarks Of Aging: 1) Mitochondrial Function

Here’s my latest video!


The Hallmarks of Aging are well established, but what is less discussed is the impact of microbes and/or microbial products. The bacterial metabolite, LPS, increases during aging, and it negatively impacts mitochondrial function, thereby demonstrating a role for microbial products on one of the Hallmarks of Aging, mitochondrial dysfunction.

Do you know you lose about 1% of your bone density each year from your thirties onwards?

I am sure you know weak bones break more easily, and the older you get the worse any extended periods of inactivity are, on not just your present health and well being, but also your longevity.

So whether you are lifting free weights for the fun of it, using your body weight in a home scenario or engaging in daily activities you know are physically taxing, you should really be incorporating some form of strength training in your plans for longevity.

Can You Upload Your Mind & Live Forever? feat. Cyberpunk 2077

Get your copy of Cyberpunk 2077 here:
http://cyberpunk.net/buy.

Sources & further reading:
https://sites.google.com/view/sources-mindupload.

The desire to be free from the limits of the human experience is as old as our first stories. We exist in an endless universe, only bound by the laws of physics and yet, our consciousness is trapped in mortal machines made of meat. With the breathtaking explosion of innovation and progress, for the first time the concept of leaving our flesh piles behind and uploading our minds into a digital utopia seems possible. Even like the logical next step on our evolutionary ladder.

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Biohackers Perform First Plasma Dilution Experiment on Humans

We interviewed a group of Russian biohackers who performed a plasma dilution experiment on themselves. This experiment, the first of its kind, was based on previous mouse studies by Drs. Irina and Michael Conboy.

Some molecules, while essential for various body functions, can be harmful when overproduced. Inflammatory cytokines, such as transforming growth factor beta 1 (TGF-ß1), interleukin 6 (IL6), and tumor necrosis factor alpha (TNFa) are good examples. The concentration of these cytokines in our blood rises with age, provoking inflammaging, the chronic inflammation that is associated with aging. It has been long speculated that reducing the harmful molecules in circulation can attenuate aging.

Reversing aging through cellular reprogramming!?

Nice lecture with both technical info and analogy.


Latest study from David Sinclair’s lab have used cellular reprogramming to restore vision in aged mice & more! Suggests reversing aging *may* be possible.

*Get 10% off at DoNotAge using my discount code “SHEEKEY”*
https://bit.ly/Sheekey_DoNotAgeShop.
DoNotAge are supporting my channel in the education of longevity and aging research. They also sell a variety of supplements including NMN, resveratrol, fisetin and more! smile
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TIMESTAMPS;
Intro — 00:00
Aging is loss of information — 00:45
Correction device & epigenetics — 02:49
Yamanaka factors & OSKM — 04:45
Study results from Sinclair lab — 07:25
Aging reversed? — 10:29
Working model — 12:00
Cellular reprogramming in humans? — 12:36.

REFERENCES;

Epigenetic Aging: How old is your DNA?

Dr. Steve Horvath, a professor of genetics and biostatistics at UCLA, has found a way to measure biological aging – a type of “clock” – based on the methylation pattern of an organism’s genome. Methylations are biochemical processes that modify the activity of a DNA segment without changing its sequence – a type of epigenetic change. This video primer explains the basics of epigenetic clocks, the topic of our interview with Dr. Steve Horvath, coming soon!

Get the show notes here:
https://www.foundmyfitness.com/episodes/epigenetic-clock/

Episode highlights:
• 00:00:09 — A person’s risk of disease is more dependent on their biological age than their chronological age.
• 00:00:09 — Epigenetics refers to processes that can affect gene expression without changing the DNA sequence. Methylation is a type of epigenetic change that occurs over a lifetime in a predictable way and can be used to measure biological age.
• 00:01:17 — The Horvath clock can accurately predict a person’s chronological age based on only the epigenetic information in their blood.
• 00:01:54 — The GrimAge clock can predict the risk and time of onset of cancer, heart disease, and death.
• 00:02:19 — Certain drugs can reverse a person’s epigenetic age, but the effects on biological age are unknown.
• 00:03:09 — The discovery of an anti-aging drug is on the horizon.

This New AI-Driven Quiz Predicts Your Psychological Age

A questionnaire developed by XPRIZE and Deep Longevity claims to be able to accurately predict your psychological age by using artificial intelligence (AI) to analyze your answers, which theoretically should fall close to your chronological age. The questionnaire is developed from a study published in Aging that used AI in an attempt to identify key hallmarks of psychological aging and the top risk factors that affect mortality.

While the questionnaire seems like a fun insight into whether you’re an old soul or a young gun at heart, there is an important scientific basis for an age-predicting AI. The newly developed technology represents the first AI aimed solely at using psychological aspects to predict age. The researchers hope it can contribute to understanding the role psychological clocks play in overall aging, as well as improving mental health and the feeling of youth.

“For the first time, AI can predict human psychological and subjective age and help identify the possible interventions that can be applied in order to help people feel and behave younger,” said Alex Zhavoronkov, PhD, founder and CLO of Deep Longevity and co-author of the study, in a statement.

Genetically engineered T cells could lead to therapies for autoimmune diseases

A new study has found that a novel T cell genetically engineered by University of Arizona Health Sciences researchers is able to target and attack pathogenic T cells that cause Type 1 diabetes, which could lead to new immunotherapy treatments.

The immune system fights bacteria, viruses and other pathogens by utilizing several types of T , all of which have receptors that are specific to particular antigens. On killer T cells, the receptor works in concert with three signaling modules and a coreceptor to destroy the . Michael Kuhns, Ph.D., an associate professor in the UArizona College of Medicine—Tucson Department of Immunobiology, copied the evolutionary design to engineer a five-module , or 5MCAR, T cell.

“The 5MCAR was an attempt to figure out if we could build something by biomimicry, using some of evolution’s natural pieces, and redirect T cells to do what we want them to do. We engineered a 5MCAR that would direct killer T cells to target autoimmune T cells that mediate Type 1 diabetes,” said Dr. Kuhns, who is member of the UArizona Cancer Center, BIO5 Institute and Arizona Center on Aging. “So now, a killer T cell will actually recognize another T cell. We flipped T cell-mediated immunity on its head.”

Panelists at the Healthy Masters 2020 on What Can We Do to Improve Health and Longevity

Here the video of the first discussion panel out of two, during the celebration of the Healthy Masters Conference 2020, which took place on November 29, 2020. Nuno Martins, organizer and moderator of the event, asked all panelists to comment on the following theme: What can we do to improve our health and longevity. Given the essence of the event, the question was surrounded by the objective of achieving radical life extension or super longevity. My intervention starts at minute 20:13 and in the description of the video there are all the time marks that direct to the begining of each talk.


First discussion panel out of two, during the celebration of the Healthy Masters Conference 2020 which took place on November 29, 2020.
Nuno Martins, PhD, organizer and moderator of the event, asked all panelists to comment on the following theme: What can we do to improve our health and longevity?
Given the essence of the event, the question was surrounded by the objective of achieving radical life extension or super longevity.

Panelists in order of appereance:
* Naveen Jain: Founder and CEO of Moon Express Viome (00:21)
* Nichola Conlon, PhD: CEO & Founder of Nuchido (03:28)
* Kelsey Moody, PhD: Process Oriented Drug Developer and Executive (05:18)
* Peter Fedichev, PhD: Head of the Laboratory of Biological Systems (08:38)
* James Hughes, PhD: Executive Director of the Institute for Ethics and Emerging Technologies (12:12)
* María Entraigues Abramson: Global Outreach Coordinator for the SENS Research Foundation (15:14)
* Yael Sorek-Benvesti, PhD: CEO of Mediterranean Towers Venture (18:24)
* Andrés Grases, MBA: Owner and Editor of Transhumanplus.com (20:13)
* Ines O´Donovan: Founder of the Jeunessima Lifestyle Company (23:52)
* Reason, CEO of Repair Biotecnologies (27:39)
* Odette Tonnae: Founder of YOAKE, the Healthy Lifestyle Expertise.
Simulation at MIPT (31:53)