Archive for the ‘life extension’ category: Page 3

Apr 21, 2024

Aubrey De Grey on the Buying Time Podcast with Liz and Saravanan. #shorts

Posted by in category: life extension

#longevity #science

Apr 21, 2024

New Research Reveals That Trauma Can Get “Under the Skin,” Weakening Your Muscles As You Age

Posted by in categories: life extension, neuroscience

A study from the University of Michigan has shown that traumatic experiences during childhood may get “under the skin” later in life, impairing the muscle function of people as they age.

The study examined the function of skeletal muscle of older adults paired with surveys of adverse events they had experienced in childhood. It found that people who experienced greater childhood adversity, reporting one or more adverse events, had poorer muscle metabolism later in life. The research, led by University of Michigan Institute for Social Research scientist Kate Duchowny, is published in Science Advances.

Duchowny and her co-authors used muscle tissue samples from people participating in the Study of Muscle, Mobility and Aging, or SOMMA. The study includes 879 participants over age 70 who donated muscle and fat samples as well as other biospecimens. The participants also were given a variety of questionnaires and physical and cognitive assessments, among other tests.

Apr 18, 2024

Rapamycin and Longevity: A Few Thoughts On Dosing

Posted by in categories: biotech/medical, life extension

What’s the optimal way to dose a longevity drug like rapamycin? Nils Osmar looks at some different studies that provide a possible answer:

It’s worth noting that mTORC2 is not directly inhibited by rapamycin under most circumstances, but can be under some. Some studies have found that after prolonged use, rapamycin can also begin inhibiting mTORC2 (see study: Alternative rapamycin treatment regimens mitigate the impact of rapamycin on glucose homeostasis and the immune system).

So taking breaks from rapamycin may also be beneficial.

Continue reading “Rapamycin and Longevity: A Few Thoughts On Dosing” »

Apr 18, 2024

Consequences of aging, why we die explained by Nobel biologist

Posted by in categories: ethics, life extension

Nobel Prize-winning molecular biologist Venki Ramakrishnan sat down with ABC News Live to discuss the science and ethics of extending the human lifespan.

In his new book, “Why We Die: The New Science of Aging and the Quest for Immortality,” Ramakrishnan explains why we may not want to lengthen our lives much longer.

Ramakrishnan’s thought-provoking argument is that a society where people lived for hundreds of years could potentially become stagnant, as it would consist of the same group of people living longer, raising important questions about societal dynamics and progress.

Apr 16, 2024

Accelerated aging may be a cause of increased cancers in people under 55

Posted by in categories: biotech/medical, life extension

An increase in cancers among people 55 years old and younger may be related to accelerated aging in recent generations, according to a study presented at a conference earlier this month.

Experts say years of research support this, though more questions remain to be answered.

Researchers from the Washington University in St. Louis’s medical school presented the findings from their study on accelerated aging earlier this month at the American Association for Cancer Research Annual Meeting.

Apr 15, 2024

Taking Mouse Lifespan to the Next Level Panel at Longevity Summit Dublin 2023

Posted by in category: life extension

Taking mouse lifespan to the next levelmoderatorcaitlin lewisspeakersdanique wortel / aubrey de grey / brian kennedy10:30 AM.

Apr 15, 2024

Just one pregnancy can add months to your biological age

Posted by in categories: biological, life extension

A landmark new study confirms that growing a human being in nine months takes a toll—and multiple pregnancies can have a cumulative effect.

Apr 14, 2024

Attempting To Slow The Epigenetic Pace Of Aging (13-Test Analysis)

Posted by in categories: genetics, life extension

Join us on Patreon! Links: Epigenetic Testing:

Apr 13, 2024

Fresh Mitochondria as a Parkinson’s Treatment

Posted by in categories: biotech/medical, life extension, neuroscience

Scientists have tested a novel method of providing cells with healthy mitochondria to fight Parkinson’s disease [1].

Parkinson’s disease is the second-most prevalent neurodegenerative disorder, and it affects 10 million people worldwide. The disease is age-related, as its prevalence rises rapidly in people older than 65, although some people are diagnosed much earlier. Parkinson’s disease is characterized by both motor and mental problems: tremor, rigidity (stiffness), and slowness of movement along with memory and thinking deficits.

Parkinson’s disease is caused by the loss of dopamine-producing (dopaminergic) neurons in a brain region called the substantia nigra. Therapeutic options are limited, and some of the existing ones cause nasty side effects.

Apr 11, 2024

New study finds potential targets at chromosome ends for degenerative disease prevention

Posted by in categories: biotech/medical, genetics, life extension

We depend on our cells being able to divide and multiply, whether it’s to replace sunburnt skin or replenish our blood supply and recover from injury. Chromosomes, which carry all of our genetic instructions, must be copied in a complete way during cell division. Telomeres, which cap the ends of chromosomes, play a critical role in this cell-renewal process—with a direct bearing on health and disease.

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